Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx001900 - Provider product page
- Provider
- Abbexa
- Product name
- Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody
- Antibody type
- Polyclonal
- Description
- UHRF1 Antibody is a Rabbit Polyclonal antibody against UHRF1. UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- > 1 mg/ml
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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