BS7685

antibody from Bioworld Technology, Inc
Targeting: ESRRA ERR1, ERRa, ERRalpha, ESRL1, NR3B1
Provider product page for BS7685
Western blot
Immunohistochemistry

Antibody data

Product number
BS7685 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ESRRA polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ESRRA.
Description
Estrogen related receptor alpha (ERRÏ«) is a nuclear receptor in the superfamily of ligand-regulated transcription factors and is a member of the NR3B orphan nuclear receptor subgroup (consisting of Ï«, ÉÇ and ÎÛ). ERRÏ« plays a role in modulating the estrogen signaling pathway. In addition, the expression of ERRÏ« has been shown to increase during fasting and cold exposure. ERRÏ« may be important for regulating mitochondrial biogenesis and oxidative metabolism by acting directly on genes necessary for mitochondrial function. Mice lacking ERRÏ« are unable to maintain their body temperature in the cold. ERRÏ« may also be involved in the maintenance and formation of cartilage. This information could be useful in finding therapeutic agents for a variety of diseases affecting the joints.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ESRRA protein structure - BS7685 shown in red.