Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS7685 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ESRRA polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human ESRRA.
- Description
- Estrogen related receptor alpha (ERRÏ«) is a nuclear receptor in the superfamily of ligand-regulated transcription factors and is a member of the NR3B orphan nuclear receptor subgroup (consisting of Ï«, ÉÇ and ÎÛ). ERRÏ« plays a role in modulating the estrogen signaling pathway. In addition, the expression of ERRÏ« has been shown to increase during fasting and cold exposure. ERRÏ« may be important for regulating mitochondrial biogenesis and oxidative metabolism by acting directly on genes necessary for mitochondrial function. Mice lacking ERRÏ« are unable to maintain their body temperature in the cold. ERRÏ« may also be involved in the maintenance and formation of cartilage. This information could be useful in finding therapeutic agents for a variety of diseases affecting the joints.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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