Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12533-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12533-1-AP, RRID:AB_2116758
- Product name
- HNF1B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HNF1B antibody (Cat. #12533-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Computational and functional analyses of T2D GWAS SNPs for transcription factor binding.
HNF1B-mediated repression of SLUG is suppressed by EZH2 in aggressive prostate cancer.
HNF1B inhibits cell proliferation via repression of SMAD6 expression in prostate cancer.
Definitive endoderm differentiation is promoted in suspension cultured human iPS-derived spheroids more than in adherent cells.
Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells.
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.
miR-194 regulates the proliferation and migration via targeting Hnf1β in mouse metanephric mesenchyme cells.
Complex bile duct network formation within liver decellularized extracellular matrix hydrogels.
ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.
Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids.
Molecular Mechanism Underlying the Suppression of CPB2 Expression Caused by Persistent Hepatitis C Virus RNA Replication.
Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells.
Does clear cell carcinoma of stomach exist? Clinicopathological and prognostic significance of clear cell changes in gastric adenocarcinomas.
Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.
Ovarian cancers arising from endometriosis: a microenvironmental biomarker study including ER, HNF1ß, p53, PTEN, BAF250a, and COX-2.
Hepatocyte nuclear factor 1β is a novel prognostic marker independent of the Milan criteria in transplantable hepatocellular carcinoma: a retrospective analysis based on tissue microarrays.
Clear cell carcinomas of the ovary: a multi-institutional study of 129 cases in Korea with prognostic significance of Emi1 and Galectin-3.
Cheng M, Huang X, Zhang M, Huang Q
Biochemical and biophysical research communications 2020 Mar 12;523(3):658-665
Biochemical and biophysical research communications 2020 Mar 12;523(3):658-665
HNF1B-mediated repression of SLUG is suppressed by EZH2 in aggressive prostate cancer.
Wang J, He C, Gao P, Wang S, Lv R, Zhou H, Zhou Q, Zhang K, Sun J, Fan C, Ding G, Lan F
Oncogene 2020 Feb;39(6):1335-1346
Oncogene 2020 Feb;39(6):1335-1346
HNF1B inhibits cell proliferation via repression of SMAD6 expression in prostate cancer.
Lu W, Sun J, Zhou H, Wang F, Zhao C, Li K, Fan C, Ding G, Wang J
Journal of cellular and molecular medicine 2020 Dec;24(24):14539-14548
Journal of cellular and molecular medicine 2020 Dec;24(24):14539-14548
Definitive endoderm differentiation is promoted in suspension cultured human iPS-derived spheroids more than in adherent cells.
Yabe SG, Nishida J, Fukuda S, Takeda F, Nashiro K, Ibuki M, Okochi H
The International journal of developmental biology 2019;63(6-7):271-280
The International journal of developmental biology 2019;63(6-7):271-280
Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells.
Yabe SG, Nishida J, Fukuda S, Takeda F, Nasiro K, Yasuda K, Iwasaki N, Okochi H
PloS one 2019;14(5):e0217110
PloS one 2019;14(5):e0217110
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
Liu Y, Kanyomse Q, Xie Y
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.
Chen M, Guo L, Dong D, Yu F, Zhang T, Wu B
Biochemical pharmacology 2019 Mar;161:163-172
Biochemical pharmacology 2019 Mar;161:163-172
miR-194 regulates the proliferation and migration via targeting Hnf1β in mouse metanephric mesenchyme cells.
Liu Y, Hu Y, Ni D, Liu J, Xia H, Xu L, Zhou Q, Xie Y
In vitro cellular & developmental biology. Animal 2019 Aug;55(7):512-521
In vitro cellular & developmental biology. Animal 2019 Aug;55(7):512-521
Complex bile duct network formation within liver decellularized extracellular matrix hydrogels.
Lewis PL, Su J, Yan M, Meng F, Glaser SS, Alpini GD, Green RM, Sosa-Pineda B, Shah RN
Scientific reports 2018 Aug 15;8(1):12220
Scientific reports 2018 Aug 15;8(1):12220
ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.
Drosos Y, Escobar D, Chiang MY, Roys K, Valentine V, Valentine MB, Rehg JE, Sahai V, Begley LA, Ye J, Paul L, McKinnon PJ, Sosa-Pineda B
Scientific reports 2017 Sep 11;7(1):11144
Scientific reports 2017 Sep 11;7(1):11144
Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids.
Nikolić MZ, Caritg O, Jeng Q, Johnson JA, Sun D, Howell KJ, Brady JL, Laresgoiti U, Allen G, Butler R, Zilbauer M, Giangreco A, Rawlins EL
eLife 2017 Jun 30;6
eLife 2017 Jun 30;6
Molecular Mechanism Underlying the Suppression of CPB2 Expression Caused by Persistent Hepatitis C Virus RNA Replication.
Sejima H, Satoh S, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N
Acta medica Okayama 2016;70(2):75-88
Acta medica Okayama 2016;70(2):75-88
Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells.
Omata M, Doke Y, Yamada C, Kawashima K, Sho R, Enomoto K, Furuya M, Inomata N
PloS one 2016;11(5):e0154912
PloS one 2016;11(5):e0154912
Does clear cell carcinoma of stomach exist? Clinicopathological and prognostic significance of clear cell changes in gastric adenocarcinomas.
Kim JY, Park DY, Kim GH, Jeon TY, Lauwers GY
Histopathology 2014 Jul;65(1):90-9
Histopathology 2014 Jul;65(1):90-9
Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.
Seth A, Ye J, Yu N, Guez F, Bedford DC, Neale GA, Cordi S, Brindle PK, Lemaigre FP, Kaestner KH, Sosa-Pineda B
Development (Cambridge, England) 2014 Feb;141(3):538-47
Development (Cambridge, England) 2014 Feb;141(3):538-47
Ovarian cancers arising from endometriosis: a microenvironmental biomarker study including ER, HNF1ß, p53, PTEN, BAF250a, and COX-2.
Lai CR, Hsu CY, Chen YJ, Yen MS, Chao KC, Li AF
Journal of the Chinese Medical Association : JCMA 2013 Nov;76(11):629-34
Journal of the Chinese Medical Association : JCMA 2013 Nov;76(11):629-34
Hepatocyte nuclear factor 1β is a novel prognostic marker independent of the Milan criteria in transplantable hepatocellular carcinoma: a retrospective analysis based on tissue microarrays.
Shim JH, Lee HC, Han S, Kang HJ, Yu E, Lee SG
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2013 Mar;19(3):336-45
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2013 Mar;19(3):336-45
Clear cell carcinomas of the ovary: a multi-institutional study of 129 cases in Korea with prognostic significance of Emi1 and Galectin-3.
Min KW, Park MH, Hong SR, Lee H, Kwon SY, Hong SH, Joo HJ, Park IA, An HJ, Suh KS, Oh HK, Yoo CW, Kim MJ, Chang HK, Jun SY, Yoon HK, Chang ED, Kim DW, Kim I, Gynecologic Pathology Study Group of the Korean Society of Pathologists.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2013 Jan;32(1):3-14
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2013 Jan;32(1):3-14
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 12533-1-AP(HNF1B antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HNF1B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HNF1B. This antibody recognizes human,mouse,rat antigen. The HNF1B antibody has been validated for the following applications: ELISA, WB, IHC analysis.