BS6827

antibody from Bioworld Technology, Inc
Targeting: PTPN6 HCP, HCPH, PTP-1C, SHP-1, SHP1
Provider product page for BS6827
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6827 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SHP 1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 550-600 of Human EphA2.
Description
SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells. The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain. SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways. In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PTPN6 protein structure - BS6827 shown in red.