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- Antibody Data
- Antigen structure
- References [55]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 10914-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10914-1-AP, RRID:AB_2230330
- Product name
- DACH1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DACH1 antibody (Cat. #10914-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes.
Derivation of Multipotent Neural Progenitors from Human Embryonic Stem Cells for Cell Therapy and Biomedical Applications.
Podometrics in Japanese Living Donor Kidneys: Associations with Nephron Number, Age, and Hypertension.
DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity.
Generation of Human iPSC-derived Neural Progenitor Cells (NPCs) as Drug Discovery Model for Neurological and Mitochondrial Disorders.
Diastolic dysfunction in a pre-clinical model of diabetes is associated with changes in the cardiac non-myocyte cellular composition.
Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling.
CXCL1 as an Unfavorable Prognosis Factor Negatively Regulated by DACH1 in Non-small Cell Lung Cancer.
A single-cell transcriptional roadmap for cardiopharyngeal fate diversification.
Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool.
Global polysome analysis of normal and injured podocytes.
Expression of transcription factors and signaling molecules in the cerebellar granule cell development.
MicroRNA-6807-3p promotes the tumorigenesis of glioma by targeting downstream DACH1.
Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis.
Modulation of inflammatory and hormonal parameters in response to testosterone therapy: Effects on the ventral prostate of adult rats.
CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart.
Dachshund 1 is Differentially Expressed Between Male and Female Breast Cancer: A Matched Case-Control Study of Clinical Characteristics and Prognosis.
Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity.
Single-cell analysis of early progenitor cells that build coronary arteries.
Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease.
DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis.
Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts.
CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis.
Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders.
Breathing control center neurons that promote arousal in mice.
DACH1 suppresses breast cancer as a negative regulator of CD44.
DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis.
Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions.
Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein.
Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity.
Inhibition of DACH1 activity by short hairpin RNA represses cell proliferation and tumor invasion in pancreatic cancer.
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Partial Dedifferentiation of Murine Radial Glia-Type Neural Stem Cells by Brn2 and c-Myc Yields Early Neuroepithelial Progenitors.
Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy.
The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module.
DACH1 inhibits lung adenocarcinoma invasion and tumor growth by repressing CXCL5 signaling.
Androgen therapy reverses injuries caused by ethanol consumption in the prostate: testosterone as a possible target to ethanol-related disorders.
Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling.
DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling.
Silencing DACH1 promotes esophageal cancer growth by inhibiting TGF-β signaling.
DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells.
Auto-attraction of neural precursors and their neuronal progeny impairs neuronal migration.
Epigenetic silencing of DACH1 induces the invasion and metastasis of gastric cancer by activating TGF-β signalling.
The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis.
APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.
Embryonic stem cell-based modeling of tau pathology in human neurons.
MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells.
Dachshund binds p53 to block the growth of lung adenocarcinoma cells.
Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency.
Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer.
Specification of functional cranial placode derivatives from human pluripotent stem cells.
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.
Dachshund homologues play a conserved role in islet cell development.
A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration.
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
Wang X, Dou N, Wang J, Zhang Y, Li Y, Gao Y
International journal of biological sciences 2021;17(4):915-925
International journal of biological sciences 2021;17(4):915-925
Derivation of Multipotent Neural Progenitors from Human Embryonic Stem Cells for Cell Therapy and Biomedical Applications.
Vitillo L, Vallier L
Methods in molecular biology (Clifton, N.J.) 2021 May 5;
Methods in molecular biology (Clifton, N.J.) 2021 May 5;
Podometrics in Japanese Living Donor Kidneys: Associations with Nephron Number, Age, and Hypertension.
Haruhara K, Sasaki T, de Zoysa N, Okabayashi Y, Kanzaki G, Yamamoto I, Harper IS, Puelles VG, Shimizu A, Cullen-McEwen LA, Tsuboi N, Yokoo T, Bertram JF
Journal of the American Society of Nephrology : JASN 2021 May 3;32(5):1187-1199
Journal of the American Society of Nephrology : JASN 2021 May 3;32(5):1187-1199
DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity.
Cao A, Li J, Asadi M, Basgen JM, Zhu B, Yi Z, Jiang S, Doke T, El Shamy O, Patel N, Cravedi P, Azeloglu EU, Campbell KN, Menon M, Coca S, Zhang W, Wang H, Zen K, Liu Z, Murphy B, He JC, D'Agati VD, Susztak K, Kaufman L
The Journal of clinical investigation 2021 May 17;131(10)
The Journal of clinical investigation 2021 May 17;131(10)
Generation of Human iPSC-derived Neural Progenitor Cells (NPCs) as Drug Discovery Model for Neurological and Mitochondrial Disorders.
Zink A, Lisowski P, Prigione A
Bio-protocol 2021 Mar 5;11(5):e3939
Bio-protocol 2021 Mar 5;11(5):e3939
Diastolic dysfunction in a pre-clinical model of diabetes is associated with changes in the cardiac non-myocyte cellular composition.
Cohen CD, De Blasio MJ, Lee MKS, Farrugia GE, Prakoso D, Krstevski C, Deo M, Donner DG, Kiriazis H, Flynn MC, Gaynor TL, Murphy AJ, Drummond GR, Pinto AR, Ritchie RH
Cardiovascular diabetology 2021 Jun 1;20(1):116
Cardiovascular diabetology 2021 Jun 1;20(1):116
Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling.
Hu X, Zhang L, Li Y, Ma X, Dai W, Gao X, Rao X, Fu G, Wang R, Pan M, Guo Q, Xu X, Zhou Y, Gao J, Zhang Z, Cai S, Peng J, Hua G
EBioMedicine 2020 Jun;56:102800
EBioMedicine 2020 Jun;56:102800
CXCL1 as an Unfavorable Prognosis Factor Negatively Regulated by DACH1 in Non-small Cell Lung Cancer.
Yu S, Yi M, Xu L, Qin S, Li A, Wu K
Frontiers in oncology 2019;9:1515
Frontiers in oncology 2019;9:1515
A single-cell transcriptional roadmap for cardiopharyngeal fate diversification.
Wang W, Niu X, Stuart T, Jullian E, Mauck WM 3rd, Kelly RG, Satija R, Christiaen L
Nature cell biology 2019 Jun;21(6):674-686
Nature cell biology 2019 Jun;21(6):674-686
Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool.
Jiao X, Li Z, Wang M, Katiyar S, Di Sante G, Farshchian M, South AP, Cocola C, Colombo D, Reinbold R, Zucchi I, Wu K, Tabas I, Spike BT, Pestell RG
Stem cell reports 2019 Jan 8;12(1):135-151
Stem cell reports 2019 Jan 8;12(1):135-151
Global polysome analysis of normal and injured podocytes.
Okabe M, Motojima M, Miyazaki Y, Pastan I, Yokoo T, Matsusaka T
American journal of physiology. Renal physiology 2019 Feb 1;316(2):F241-F252
American journal of physiology. Renal physiology 2019 Feb 1;316(2):F241-F252
Expression of transcription factors and signaling molecules in the cerebellar granule cell development.
Shiraishi RD, Miyashita S, Yamashita M, Adachi T, Shimoda MM, Owa T, Hoshino M
Gene expression patterns : GEP 2019 Dec;34:119068
Gene expression patterns : GEP 2019 Dec;34:119068
MicroRNA-6807-3p promotes the tumorigenesis of glioma by targeting downstream DACH1.
Lu GF, Geng F, Xiao Z, Chen YS, Han Y, You CY, Gong NL, Xie ZM, Pan M
Brain research 2019 Apr 1;1708:47-57
Brain research 2019 Apr 1;1708:47-57
Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis.
Qin G, Lian J, Huang L, Zhao Q, Liu S, Zhang Z, Chen X, Yue D, Li L, Li F, Wang L, Umansky V, Zhang B, Yang S, Zhang Y
Oncoimmunology 2018;7(7):e1442167
Oncoimmunology 2018;7(7):e1442167
Modulation of inflammatory and hormonal parameters in response to testosterone therapy: Effects on the ventral prostate of adult rats.
Mendes LO, Castilho ACS, Pinho CF, Gonçalvez BF, Razza EM, Chuffa LGA, Anselmo-Franci JA, Scarano WR, Martinez FE
Cell biology international 2018 Sep;42(9):1200-1211
Cell biology international 2018 Sep;42(9):1200-1211
CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart.
Bonet F, Pereira PNG, Bover O, Marques S, Inácio JM, Belo JA
Developmental dynamics : an official publication of the American Association of Anatomists 2018 Oct;247(10):1135-1145
Developmental dynamics : an official publication of the American Association of Anatomists 2018 Oct;247(10):1135-1145
Dachshund 1 is Differentially Expressed Between Male and Female Breast Cancer: A Matched Case-Control Study of Clinical Characteristics and Prognosis.
Cui Q, Kong D, Li Z, Ahiable P, Wang K, Wu K, Wu G
Clinical breast cancer 2018 Oct;18(5):e875-e882
Clinical breast cancer 2018 Oct;18(5):e875-e882
Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity.
Poppe D, Doerr J, Schneider M, Wilkens R, Steinbeck JA, Ladewig J, Tam A, Paschon DE, Gregory PD, Reik A, Müller CE, Koch P, Brüstle O
Stem cells translational medicine 2018 Jun;7(6):477-486
Stem cells translational medicine 2018 Jun;7(6):477-486
Single-cell analysis of early progenitor cells that build coronary arteries.
Su T, Stanley G, Sinha R, D'Amato G, Das S, Rhee S, Chang AH, Poduri A, Raftrey B, Dinh TT, Roper WA, Li G, Quinn KE, Caron KM, Wu S, Miquerol L, Butcher EC, Weissman I, Quake S, Red-Horse K
Nature 2018 Jul;559(7714):356-362
Nature 2018 Jul;559(7714):356-362
Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease.
Rhee S, Chung JI, King DA, D'amato G, Paik DT, Duan A, Chang A, Nagelberg D, Sharma B, Jeong Y, Diehn M, Wu JC, Morrison AJ, Red-Horse K
Nature communications 2018 Jan 25;9(1):368
Nature communications 2018 Jan 25;9(1):368
DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis.
Liu Q, Li A, Yu S, Qin S, Han N, Pestell RG, Han X, Wu K
Journal of hematology & oncology 2018 Apr 10;11(1):53
Journal of hematology & oncology 2018 Apr 10;11(1):53
Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts.
Sharma B, Ho L, Ford GH, Chen HI, Goldstone AB, Woo YJ, Quertermous T, Reversade B, Red-Horse K
Developmental cell 2017 Sep 25;42(6):655-666.e3
Developmental cell 2017 Sep 25;42(6):655-666.e3
CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis.
Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I
The Journal of clinical investigation 2017 Nov 1;127(11):4075-4089
The Journal of clinical investigation 2017 Nov 1;127(11):4075-4089
Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders.
Lorenz C, Lesimple P, Bukowiecki R, Zink A, Inak G, Mlody B, Singh M, Semtner M, Mah N, Auré K, Leong M, Zabiegalov O, Lyras EM, Pfiffer V, Fauler B, Eichhorst J, Wiesner B, Huebner N, Priller J, Mielke T, Meierhofer D, Izsvák Z, Meier JC, Bouillaud F, Adjaye J, Schuelke M, Wanker EE, Lombès A, Prigione A
Cell stem cell 2017 May 4;20(5):659-674.e9
Cell stem cell 2017 May 4;20(5):659-674.e9
Breathing control center neurons that promote arousal in mice.
Yackle K, Schwarz LA, Kam K, Sorokin JM, Huguenard JR, Feldman JL, Luo L, Krasnow MA
Science (New York, N.Y.) 2017 Mar 31;355(6332):1411-1415
Science (New York, N.Y.) 2017 Mar 31;355(6332):1411-1415
DACH1 suppresses breast cancer as a negative regulator of CD44.
Xu H, Yu S, Yuan X, Xiong J, Kuang D, Pestell RG, Wu K
Scientific reports 2017 Jun 28;7(1):4361
Scientific reports 2017 Jun 28;7(1):4361
DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis.
Chang AH, Raftrey BC, D'Amato G, Surya VN, Poduri A, Chen HI, Goldstone AB, Woo J, Fuller GG, Dunn AR, Red-Horse K
Genes & development 2017 Jul 1;31(13):1308-1324
Genes & development 2017 Jul 1;31(13):1308-1324
Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions.
Isoda M, Kohyama J, Iwanami A, Sanosaka T, Sugai K, Yamaguchi R, Matsumoto T, Nakamura M, Okano H
Neuroscience research 2016 Sep;110:18-28
Neuroscience research 2016 Sep;110:18-28
Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein.
Ben Halima S, Mishra S, Raja KMP, Willem M, Baici A, Simons K, Brüstle O, Koch P, Haass C, Caflisch A, Rajendran L
Cell reports 2016 Mar 8;14(9):2127-2141
Cell reports 2016 Mar 8;14(9):2127-2141
Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity.
Liu QQ, Zhou YQ, Liu HQ, Qiu WH, Liu H, Hu TY, Xu Q, Lv YM, Wu KM
Oncotarget 2016 Dec 27;7(52):86547-86560
Oncotarget 2016 Dec 27;7(52):86547-86560
Inhibition of DACH1 activity by short hairpin RNA represses cell proliferation and tumor invasion in pancreatic cancer.
Bu XN, Qiu C, Wang C, Jiang Z
Oncology reports 2016 Aug;36(2):745-54
Oncology reports 2016 Aug;36(2):745-54
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Lyons SM, Achorn C, Kedersha NL, Anderson PJ, Ivanov P
Nucleic acids research 2016 Aug 19;44(14):6949-60
Nucleic acids research 2016 Aug 19;44(14):6949-60
Partial Dedifferentiation of Murine Radial Glia-Type Neural Stem Cells by Brn2 and c-Myc Yields Early Neuroepithelial Progenitors.
Bung R, Wörsdörfer P, Thier MC, Lemke K, Gebhardt M, Edenhofer F
Journal of molecular biology 2016 Apr 10;428(7):1476-83
Journal of molecular biology 2016 Apr 10;428(7):1476-83
Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy.
Doerr J, Böckenhoff A, Ewald B, Ladewig J, Eckhardt M, Gieselmann V, Matzner U, Brüstle O, Koch P
Molecular therapy : the journal of the American Society of Gene Therapy 2015 Sep;23(9):1519-31
Molecular therapy : the journal of the American Society of Gene Therapy 2015 Sep;23(9):1519-31
The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module.
Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, Di Sante G, Xu S, Wang Q, Li K, Sun X, Xu C, Li Z, Casimiro MC, Ertel A, Addya S, McCue PA, Lisanti MP, Wang C, Davis RJ, Mardon G, Pestell RG
Cancer research 2015 May 15;75(10):1992-2004
Cancer research 2015 May 15;75(10):1992-2004
DACH1 inhibits lung adenocarcinoma invasion and tumor growth by repressing CXCL5 signaling.
Han N, Yuan X, Wu H, Xu H, Chu Q, Guo M, Yu S, Chen Y, Wu K
Oncotarget 2015 Mar 20;6(8):5877-88
Oncotarget 2015 Mar 20;6(8):5877-88
Androgen therapy reverses injuries caused by ethanol consumption in the prostate: testosterone as a possible target to ethanol-related disorders.
Mendes LO, Scarano WR, Rochel-Maia SS, Fioruci-Fontaneli BA, Chuffa LG, Anselmo-Franci JA, Martinez FE
Life sciences 2015 Jan 1;120:22-30
Life sciences 2015 Jan 1;120:22-30
Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling.
Maneix L, Antonson P, Humire P, Rochel-Maia S, Castañeda J, Omoto Y, Kim HJ, Warner M, Gustafsson JÅ
Proceedings of the National Academy of Sciences of the United States of America 2015 Apr 21;112(16):5135-40
Proceedings of the National Academy of Sciences of the United States of America 2015 Apr 21;112(16):5135-40
DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling.
Liu Y, Zhou R, Yuan X, Han N, Zhou S, Xu H, Guo M, Yu S, Zhang C, Yin T, Wu K
Oncotarget 2015 Apr 20;6(11):8621-34
Oncotarget 2015 Apr 20;6(11):8621-34
Silencing DACH1 promotes esophageal cancer growth by inhibiting TGF-β signaling.
Wu L, Herman JG, Brock MV, Wu K, Mao G, Yan W, Nie Y, Liang H, Zhan Q, Li W, Guo M
PloS one 2014;9(4):e95509
PloS one 2014;9(4):e95509
DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells.
Chu Q, Han N, Yuan X, Nie X, Wu H, Chen Y, Guo M, Yu S, Wu K
Journal of hematology & oncology 2014 Oct 17;7:73
Journal of hematology & oncology 2014 Oct 17;7:73
Auto-attraction of neural precursors and their neuronal progeny impairs neuronal migration.
Ladewig J, Koch P, Brüstle O
Nature neuroscience 2014 Jan;17(1):24-6
Nature neuroscience 2014 Jan;17(1):24-6
Epigenetic silencing of DACH1 induces the invasion and metastasis of gastric cancer by activating TGF-β signalling.
Yan W, Wu K, Herman JG, Brock MV, Zhou Y, Lu Y, Zhang Z, Yang Y, Guo M
Journal of cellular and molecular medicine 2014 Dec;18(12):2499-511
Journal of cellular and molecular medicine 2014 Dec;18(12):2499-511
The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis.
Chen HI, Sharma B, Akerberg BN, Numi HJ, Kivelä R, Saharinen P, Aghajanian H, McKay AS, Bogard PE, Chang AH, Jacobs AH, Epstein JA, Stankunas K, Alitalo K, Red-Horse K
Development (Cambridge, England) 2014 Dec;141(23):4500-12
Development (Cambridge, England) 2014 Dec;141(23):4500-12
APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.
Mertens J, Stüber K, Wunderlich P, Ladewig J, Kesavan JC, Vandenberghe R, Vandenbulcke M, van Damme P, Walter J, Brüstle O, Koch P
Stem cell reports 2013;1(6):491-8
Stem cell reports 2013;1(6):491-8
Embryonic stem cell-based modeling of tau pathology in human neurons.
Mertens J, Stüber K, Poppe D, Doerr J, Ladewig J, Brüstle O, Koch P
The American journal of pathology 2013 May;182(5):1769-79
The American journal of pathology 2013 May;182(5):1769-79
MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells.
Zhou Y, Jiang H, Gu J, Tang Y, Shen N, Jin Y
Cell death & disease 2013 Jun 27;4:e695
Cell death & disease 2013 Jun 27;4:e695
Dachshund binds p53 to block the growth of lung adenocarcinoma cells.
Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG
Cancer research 2013 Jun 1;73(11):3262-74
Cancer research 2013 Jun 1;73(11):3262-74
Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency.
Tailor J, Kittappa R, Leto K, Gates M, Borel M, Paulsen O, Spitzer S, Karadottir RT, Rossi F, Falk A, Smith A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jul 24;33(30):12407-22
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jul 24;33(30):12407-22
Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer.
Yan W, Wu K, Herman JG, Brock MV, Fuks F, Yang L, Zhu H, Li Y, Yang Y, Guo M
Epigenetics 2013 Dec;8(12):1373-83
Epigenetics 2013 Dec;8(12):1373-83
Specification of functional cranial placode derivatives from human pluripotent stem cells.
Dincer Z, Piao J, Niu L, Ganat Y, Kriks S, Zimmer B, Shi SH, Tabar V, Studer L
Cell reports 2013 Dec 12;5(5):1387-402
Cell reports 2013 Dec 12;5(5):1387-402
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.
Koch P, Breuer P, Peitz M, Jungverdorben J, Kesavan J, Poppe D, Doerr J, Ladewig J, Mertens J, Tüting T, Hoffmann P, Klockgether T, Evert BO, Wüllner U, Brüstle O
Nature 2011 Nov 23;480(7378):543-6
Nature 2011 Nov 23;480(7378):543-6
Dachshund homologues play a conserved role in islet cell development.
Kalousova A, Mavropoulos A, Adams BA, Nekrep N, Li Z, Krauss S, Stainier DY, German MS
Developmental biology 2010 Dec 15;348(2):143-52
Developmental biology 2010 Dec 15;348(2):143-52
A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration.
Koch P, Opitz T, Steinbeck JA, Ladewig J, Brüstle O
Proceedings of the National Academy of Sciences of the United States of America 2009 Mar 3;106(9):3225-30
Proceedings of the National Academy of Sciences of the United States of America 2009 Mar 3;106(9):3225-30
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L
Genes & development 2008 Jan 15;22(2):152-65
Genes & development 2008 Jan 15;22(2):152-65
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10914-1-AP(DACH1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-DACH1 (IP:10914-1-AP, 4ug; Detection:10914-1-AP 1:1000) with HEK-293 cells lysate 6000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DACH1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DACH1. This antibody recognizes human,mouse,rat antigen. The DACH1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
