Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-8083 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Dach1 Antibody
- Antibody type
- Polyclonal
- Description
- DACH1, originally discovered in drosophila eye development, is an essential member of RDGN (Retinal Determination Gene Network). This protein behaves as a tumor suppressor, and its expression is reduced in several cancers. The ectopic expression of DACH1 inhibits cellular proliferation in vitro and tumor growth in vivo. DACH1 is richly expressed in embryonal kidney cells and adult kidney tissues, but dramatically decreases in renal cancer cells.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant Dach1
protein (amino acids 300-550) was u
sed as the immunogen for this antib
ody.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of Dach1. Anti-Dach1 antibody (11-8083) was used at 4 µg/ml on (1) MCF-7 and (2) Testis lysates.