11-8083-25

antibody from ABEOMICS Inc.

Targeting: DACH1 DACH

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

11-8083-25

Provider

ABEOMICS Inc.

Product name

Anti-Dach1 Antibody

Antibody type

Polyclonal

Description

DACH1, originally discovered in drosophila eye development, is an essential member of RDGN (Retinal Determination Gene Network). This protein behaves as a tumor suppressor, and its expression is reduced in several cancers. The ectopic expression of DACH1 inhibits cellular proliferation in vitro and tumor growth in vivo. DACH1 is richly expressed in embryonal kidney cells and adult kidney tissues, but dramatically decreases in renal cancer cells.

Reactivity

Human

Host

Rabbit

Antigen sequence

A partial length recombinant Dach1
protein (amino acids 300-550) was u
sed as the immunogen for this antib
ody.


Vial size

25 µg

Concentration

0.5 mg/ml

Storage

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing

Western blot

Supportive validation

Submitted by

ABEOMICS Inc. (provider)

Main image

Experimental details

Western blot analysis of Dach1. Anti-Dach1 antibody (11-8083) was used at 4 µg/ml on (1) MCF-7 and (2) Testis  lysates.