AMM03895G

antibody from Leading Biology

Targeting: PCGF2 MEL-18, RNF110, ZNF144

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03895G

Provider

Leading Biology

Product name

PCGF2 Antibody (monoclonal) (M04)

Antibody type

Monoclonal

Description

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Reactivity

Human, Rat

Host

Mouse

Isotype

IgG

Antibody clone number

4C10

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.