Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 14246-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14246-1-AP, RRID:AB_2155476
- Product name
- NR2E3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NR2E3 antibody (Cat. #14246-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries.
Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer.
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.
Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.
Khanal T, Leung YK, Jiang W, Timchenko N, Ho SM, Kim K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8335-8348
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8335-8348
Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer.
Khanal T, Choi K, Leung YK, Wang J, Kim D, Janakiram V, Cho SG, Puga A, Ho SM, Kim K
Scientific reports 2017 Sep 6;7(1):10662
Scientific reports 2017 Sep 6;7(1):10662
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.
Cho KI, Patil H, Senda E, Wang J, Yi H, Qiu S, Yoon D, Yu M, Orry A, Peachey NS, Ferreira PA
The Journal of biological chemistry 2014 Feb 21;289(8):4600-25
The Journal of biological chemistry 2014 Feb 21;289(8):4600-25
Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.
Cho KI, Haque M, Wang J, Yu M, Hao Y, Qiu S, Pillai IC, Peachey NS, Ferreira PA
PLoS genetics 2013 Jun;9(6):e1003555
PLoS genetics 2013 Jun;9(6):e1003555
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 14246-1-AP(NR2E3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 14246-1-AP(NR2E3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NR2E3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NR2E3. This antibody recognizes human, mouse, rat antigen. The NR2E3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.