FNab07153

antibody from FineTest Biotech

Targeting: RBBP8 COM1, CtIP, RIM, SCKL2

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab07153 - Provider product page
Provider: FineTest Biotech
Product name: RBBP8 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Endonuclease that cooperates with the MRE11-RAD50-NBN(MRN) complex in processing meiotic and mitotic double-strand breaks(DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining(A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: retinoblastoma binding protein 8
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RBBP8 protein structure - FNab07153 shown in red.