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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunohistochemistry [2]
- Other assay [1]
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- Product number
- V2760 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Neurofilament Antibody
- Antibody type
- Monoclonal
- Antigen
- Crude neurofilament preparation from porcine spinal cord was used as the immunogen for the Neurofilament antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Rat, Bovine, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- NR-4
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the Neurofilament antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references High postnatal susceptibility of hippocampal cytoskeleton in response to ethanol exposure during pregnancy and lactation.
Neuroprotective Effect of Calpeptin on Acrylamide-Induced Neuropathy in Rats.
Decelerated transport and its mechanism of 2,5-hexanedione on middle-molecular-weight neurofilament in rat dorsal root ganglia cells.
Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice.
Disrupted cytoskeletal homeostasis, astrogliosis and apoptotic cell death in the cerebellum of preweaning rats injected with diphenyl ditelluride.
The C-terminal domains of NF-H and NF-M subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament network.
Exposure of young rats to diphenyl ditelluride during lactation affects the homeostasis of the cytoskeleton in neural cells from striatum and cerebellum.
In vivo treatment with diphenyl ditelluride induces neurodegeneration in striatum of young rats: implications of MAPK and Akt pathways.
Reis KP, Heimfarth L, Pierozan P, Ferreira F, Loureiro SO, Fernandes CG, Carvalho RV, Pessoa-Pureur R
Alcohol (Fayetteville, N.Y.) 2015 Nov;49(7):665-74
Alcohol (Fayetteville, N.Y.) 2015 Nov;49(7):665-74
Neuroprotective Effect of Calpeptin on Acrylamide-Induced Neuropathy in Rats.
Wei X, Yan F, E M, Zhang C, Li G, Yang X, Zhang F, Wang S, Yu S
Neurochemical research 2015 Nov;40(11):2325-32
Neurochemical research 2015 Nov;40(11):2325-32
Decelerated transport and its mechanism of 2,5-hexanedione on middle-molecular-weight neurofilament in rat dorsal root ganglia cells.
Han XY, Cheng D, Song FY, Zeng T, An LH, Xie KQ
Neuroscience 2014 Jun 6;269:192-8
Neuroscience 2014 Jun 6;269:192-8
Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice.
Rao MV, McBrayer MK, Campbell J, Kumar A, Hashim A, Sershen H, Stavrides PH, Ohno M, Hutton M, Nixon RA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Jul 9;34(28):9222-34
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Jul 9;34(28):9222-34
Disrupted cytoskeletal homeostasis, astrogliosis and apoptotic cell death in the cerebellum of preweaning rats injected with diphenyl ditelluride.
Heimfarth L, Loureiro SO, Dutra MF, Petenuzzo L, de Lima BO, Fernandes CG, da Rocha JB, Pessoa-Pureur R
Neurotoxicology 2013 Jan;34:175-88
Neurotoxicology 2013 Jan;34:175-88
The C-terminal domains of NF-H and NF-M subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament network.
Rao MV, Yuan A, Campbell J, Kumar A, Nixon RA
PloS one 2012;7(9):e44320
PloS one 2012;7(9):e44320
Exposure of young rats to diphenyl ditelluride during lactation affects the homeostasis of the cytoskeleton in neural cells from striatum and cerebellum.
Heimfarth L, Reis KP, Loureiro SO, de Lima BO, da Rocha JB, Pessoa-Pureur R
Neurotoxicology 2012 Oct;33(5):1106-16
Neurotoxicology 2012 Oct;33(5):1106-16
In vivo treatment with diphenyl ditelluride induces neurodegeneration in striatum of young rats: implications of MAPK and Akt pathways.
Heimfarth L, Loureiro SO, Dutra MF, Andrade C, Pettenuzzo L, Guma FT, Gonçalves CA, da Rocha JB, Pessoa-Pureur R
Toxicology and applied pharmacology 2012 Oct 15;264(2):143-52
Toxicology and applied pharmacology 2012 Oct 15;264(2):143-52
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of formalin-fixed, paraffin-embedded human cerebellum stained with Neurofilament antibody (NR-4).
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of formalin-fixed, paraffin-embedded rat cerebellum stained with Neurofilament antibody (NR-4).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free Neurofilament Antibody (clone NR-4). Confirmation of Integrity and Purity of the Antibody.
