abx015936

antibody from Abbexa

Targeting: NEFL CMT1F, CMT2E, NF68, NFL, PPP1R110

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx015936

Provider

Abbexa

Product name

Neurofilament, Light Polypeptide (NEFL) Antibody

Antibody type

Monoclonal

Description

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains.Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber.They may also play a role in intracellular transport to axons and dendrites.This gene encodes the light chain neurofilament protein.Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies.A pseudogene has been identified on chromosome Y.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.