BS2784

antibody from Bioworld Technology, Inc
Targeting: ADGRB1 BAI1
Provider product page for BS2784
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS2784 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2784, RRID:AB_1663799
Product name
BAI 1 (Q732) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 711-760 of Human BAI-1.
Description
Brain-specific angiogenesis inhibitors, including BAI-1, BAI-2 and BAI-3, are integral membrane proteins belonging to the G protein-coupled receptor 2 family. In addition to inhibiting angiogenesis in the brain, BAI proteins are also expressed in the heart, thymus, skeletal muscle, and a variety of cell lines. BAI-1 protein is specifically expressed in the brain and found to localize to the cytoplasm and membrane in neuronal cells of the cerebral cortex. Reduced expression of BAI-1 in some glioblastoma cell lines and cancer tissues implicates the functional role of BAI-1 as an inhibitor of angiogenesis. The exact mechanisms underlying BAI-1 anti-angiogenetic activity are still being investigated. BAI-1 may be involved in mediating the p53 signal in suppression of glioblastoma, as well as in cell adhesion and signal transduction. Additional research shows an inverse correlation with vascularization and BAI-1 expression in both colorectal carcinomas and pulmonary adenocarcinomas.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ADGRB1 protein structure - BS2784 shown in red.