BS4807

antibody from Bioworld Technology, Inc

Targeting: PRAG1 DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223

Western blot (Data presented on provider website)

Antibody Data

Product number

BS4807

Provider

Bioworld Technology, Inc

Product name

Pragmin (phospho Y413) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic phosphopeptide derived from human Pragmin around the phosphorylation site of Tyrosine 413.

Description

The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its role in signal transduction pathways and high frequency of mutations in human malignancies. The founding members of the Ras family (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The mammalian Rho proteins (Rho A, B, C, 6, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Three Rho-related GTPases Rnd1 (Rho 6), Rnd2 (Rho 7), and Rnd3 (Rho 8 or Rho E) form a distinct branch of the Rho family since they differ from other Rho proteins in size, charge, and biochemical properties.

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.