PA5-53730
antibody from Invitrogen Antibodies
Targeting: SLC4A11
BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- PA5-53730 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- SLC4A11 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: TNTENEATSG GCVLLHTSRK YLKLKNFKEE IRAHRDLDGF LAQASIVLNE TATSLDNVLR TMLRRFARDP DNNEPNCNLD LLMAMLFTDA GAPMRGKVHL L Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 78%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Vps35-deficiency impairs SLC4A11 trafficking and promotes corneal dystrophy.
Liu W, Tang FL, Lin S, Zhao K, Mei L, Ye J, Xiong WC
PloS one 2017;12(9):e0184906
PloS one 2017;12(9):e0184906
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of SLC4A11 in human testis tissue shows strong positivity in Leydig cells. Samples were probed using a SLC4A11 Polyclonal Antibody (Product # PA5-53730).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig 5 Impaired cell surface targeting of SLC4A11 in Vps35-deficient cells and reduced SLC4A11 in Vps35-deficient corneal endothelium. (A-G) HEK293 cells transfected with SLC4A11-GFP with control and miRNA-Vps35 were subjected to co-immunstaining analyses using indicated antibodies. Representative confocal images were shown in (A and D); and quantification analyses (mean +/- SEM, n = 20 cells, *, p