BS6488

antibody from Bioworld Technology, Inc
Targeting: IKBKE IKK-i, IKKE, KIAA0151
Provider product page for BS6488
Western blot
Immunohistochemistry

Antibody data

Product number
BS6488 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IKBKE polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human IKBKE.
Description
The functional IKK complex contains three subunits, IKKÏ«, IKKÉÇ and IKKÎÛ (also designated NEMO), and each appear to make essential contributions to I°ÙB phosphorylation. IKK-i is a serine/threonine kinase that shares homology with IKKÏ« and IKKÉÇ. IKK-i is primarily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNFÏ«, IL-1 and IL-6. Overexpression of IKK-i was shown to result in phosphorylation of I°ÙBÏ« on Ser32 and Ser36, and in NF°ÙB activation, suggesting that IKK-i may act as an I°ÙB kinase in the immune system.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IKBKE protein structure - BS6488 shown in red.