Tissue expression
Cell line expression
Protein structure
ZNF280B
Zinc finger protein 280B5'OY11.1, SUHW2, ZNF279, ZNF632
The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]
Top validated antibodies |
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Affinity Biosciences | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Atlas Antibodies | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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