Antibody data
- Antibody Data
- Antigen structure
- References [30]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
Reference
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- Product number
- 20103-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20103-1-AP, RRID:AB_2716813
- Product name
- CD45 antibody
- Antibody type
- Polyclonal
- Description
- CD45 antibody (Cat. #20103-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Effects of nanoparticle-mediated Co-delivery of bFGF and VEGFA genes to deep burn wounds: An in vivo study.
Downregulation of Macrophage-Specific Act-1 Intensifies Periodontitis and Alveolar Bone Loss Possibly via TNF/NF-κB Signaling.
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Pathogenic Roles of CXCL10 in Experimental Autoimmune Prostatitis by Modulating Macrophage Chemotaxis and Cytokine Secretion.
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Research on the correlation between activating transcription factor 3 expression in the human coronary artery and atherosclerotic plaque stability.
SLIT2 Overexpression in Periodontitis Intensifies Inflammation and Alveolar Bone Loss, Possibly via the Activation of MAPK Pathway.
High catalytic efficiency from Er3+-doped CeO2-x nanoprobes for in vivo acute oxidative damage and inflammation therapy.
Amyloid precursor protein 770 is specifically expressed and released from platelets.
MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4.
Taxifolin improves disorders of glucose metabolism and water-salt metabolism in kidney via PI3K/AKT signaling pathway in metabolic syndrome rats.
Kallistatin correlates with inflammation in abdominal aortic aneurysm and suppresses its formation in mice.
COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells.
Colorectal Cancer Is Associated with a Deficiency of Lipoxin A4, an Endogenous Anti-inflammatory Mediator.
Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice.
Brain-to-cervical lymph node signaling after stroke.
Ectopic TWEAKR expression in type I fiber of stroke-prone spontaneously hypertensive rats is related to slow muscle-specific hypotrophy.
The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.
NRP1 regulates HMGB1 in vascular endothelial cells under high homocysteine condition.
Increased m6A methylation level is associated with the progression of human abdominal aortic aneurysm.
A self-organized actomyosin drives multiple intercellular junction disruption and directly promotes neutrophil recruitment in lipopolysaccharide-induced acute lung injury.
Inhibiting transforming growth factor-β signaling regulates in vitro maintenance and differentiation of bovine bone marrow mesenchymal stem cells.
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia.
Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes.
A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.
Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway.
Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation.
Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress.
Zhang Q, Zhang C, Feng L, Wang L, Qi J, Dong Y, Zhou YL, Hu K, Zhang Y
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 2):112135
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 2):112135
Downregulation of Macrophage-Specific Act-1 Intensifies Periodontitis and Alveolar Bone Loss Possibly via TNF/NF-κB Signaling.
Pathak JL, Fang Y, Chen Y, Ye Z, Guo X, Yan Y, Zha J, Liang D, Ke X, Yang L, Zhong W, Wang L, Wang L
Frontiers in cell and developmental biology 2021;9:628139
Frontiers in cell and developmental biology 2021;9:628139
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Zhu Q, Yuan J, He Y, Hu Y
Journal of oncology 2021;2021:5170496
Journal of oncology 2021;2021:5170496
Pathogenic Roles of CXCL10 in Experimental Autoimmune Prostatitis by Modulating Macrophage Chemotaxis and Cytokine Secretion.
Hua X, Ge S, Zhang M, Mo F, Zhang L, Zhang J, Yang C, Tai S, Chen X, Zhang L, Liang C
Frontiers in immunology 2021;12:706027
Frontiers in immunology 2021;12:706027
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Zhang Z, Zheng Y, Niu Z, Zhang B, Wang C, Yao X, Peng H, Franca DN, Wang Y, Zhu Y, Su Y, Tang M, Jiang X, Ren H, He M, Wang Y, Gao L, Zhao P, Shi H, Chen Z, Wang X, Piacentini M, Bian X, Melino G, Liu L, Huang H, Sun Q
Cell death and differentiation 2021 Sep;28(9):2765-2777
Cell death and differentiation 2021 Sep;28(9):2765-2777
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Yang W, He H, Wang T, Su N, Zhang F, Jiang K, Zhu J, Zhang C, Niu K, Wang L, Yuan X, Liu N, Li L, Wei W, Hu J
Hepatology (Baltimore, Md.) 2021 Nov;74(5):2774-2790
Hepatology (Baltimore, Md.) 2021 Nov;74(5):2774-2790
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 May 13;
CNS neuroscience & therapeutics 2021 May 13;
Research on the correlation between activating transcription factor 3 expression in the human coronary artery and atherosclerotic plaque stability.
Peng J, Le CY, Xia B, Wang JW, Liu JJ, Li Z, Zhang QJ, Zhang Q, Wang J, Wan CW
BMC cardiovascular disorders 2021 Jul 28;21(1):356
BMC cardiovascular disorders 2021 Jul 28;21(1):356
SLIT2 Overexpression in Periodontitis Intensifies Inflammation and Alveolar Bone Loss, Possibly via the Activation of MAPK Pathway.
Wang L, Zheng J, Pathak JL, Chen Y, Liang D, Yang L, Sun H, Zhong M, Wu L, Li L, Deng S, Zheng L, Yan Y, Hou D, Wang L, Ge L
Frontiers in cell and developmental biology 2020;8:593
Frontiers in cell and developmental biology 2020;8:593
High catalytic efficiency from Er3+-doped CeO2-x nanoprobes for in vivo acute oxidative damage and inflammation therapy.
Li Y, Li Y, Bai Y, Lin L, Sun Y
Journal of materials chemistry. B 2020 Sep 30;8(37):8634-8643
Journal of materials chemistry. B 2020 Sep 30;8(37):8634-8643
Amyloid precursor protein 770 is specifically expressed and released from platelets.
Miura S, Yoshihisa A, Misaka T, Yamaki T, Kojima T, Toyokawa M, Ogawa K, Shimura H, Yamamoto N, Kasahara K, Takeishi Y, Kitazume S
The Journal of biological chemistry 2020 Sep 18;295(38):13194-13201
The Journal of biological chemistry 2020 Sep 18;295(38):13194-13201
MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4.
Wu J, Li X, Li D, Ren X, Li Y, Herter EK, Qian M, Toma MA, Wintler AM, Sérézal IG, Rollman O, Ståhle M, Wikstrom JD, Ye X, Landén NX
The Journal of investigative dermatology 2020 Feb;140(2):465-476.e11
The Journal of investigative dermatology 2020 Feb;140(2):465-476.e11
Taxifolin improves disorders of glucose metabolism and water-salt metabolism in kidney via PI3K/AKT signaling pathway in metabolic syndrome rats.
Gao L, Yuan P, Zhang Q, Fu Y, Hou Y, Wei Y, Zheng X, Feng W
Life sciences 2020 Dec 15;263:118713
Life sciences 2020 Dec 15;263:118713
Kallistatin correlates with inflammation in abdominal aortic aneurysm and suppresses its formation in mice.
He Y, Han Y, Xing J, Zhai X, Wang S, Xin S, Zhang J
Cardiovascular diagnosis and therapy 2020 Apr;10(2):107-123
Cardiovascular diagnosis and therapy 2020 Apr;10(2):107-123
COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells.
Wen Y, Yang H, Wu J, Wang A, Chen X, Hu S, Zhang Y, Bai D, Jin Z
Theranostics 2019;9(15):4265-4286
Theranostics 2019;9(15):4265-4286
Colorectal Cancer Is Associated with a Deficiency of Lipoxin A4, an Endogenous Anti-inflammatory Mediator.
Liu H, Zeng J, Huang W, Xu Q, Ye D, Sun R, Zhang D
Journal of Cancer 2019;10(19):4719-4730
Journal of Cancer 2019;10(19):4719-4730
Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice.
Hempel F, Roderfeld M, Savai R, Sydykov A, Irungbam K, Schermuly R, Voswinckel R, Köhler K, Churin Y, Kiss L, Bier J, Pons-Kühnemann J, Roeb E
Cells 2019 Oct 7;8(10)
Cells 2019 Oct 7;8(10)
Brain-to-cervical lymph node signaling after stroke.
Esposito E, Ahn BJ, Shi J, Nakamura Y, Park JH, Mandeville ET, Yu Z, Chan SJ, Desai R, Hayakawa A, Ji X, Lo EH, Hayakawa K
Nature communications 2019 Nov 22;10(1):5306
Nature communications 2019 Nov 22;10(1):5306
Ectopic TWEAKR expression in type I fiber of stroke-prone spontaneously hypertensive rats is related to slow muscle-specific hypotrophy.
Inoue T, Hagiyama M, Maenishi O, Kimura M, Mizuguchi N, Mine Y, Kimura R, Chikugo T, Itoh T, Satou T, Ito A
Life sciences 2019 Nov 15;237:116919
Life sciences 2019 Nov 15;237:116919
The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.
Xu H, Du X, Liu G, Huang S, Du W, Zou S, Tang D, Fan C, Xie Y, Wei Y, Tian Y, Fu X
Molecular metabolism 2019 May;23:14-23
Molecular metabolism 2019 May;23:14-23
NRP1 regulates HMGB1 in vascular endothelial cells under high homocysteine condition.
Ma Y, Zhang Z, Chen R, Shi R, Zeng P, Chen R, Leng Y, Chen AF
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H1039-H1046
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H1039-H1046
Increased m6A methylation level is associated with the progression of human abdominal aortic aneurysm.
He Y, Xing J, Wang S, Xin S, Han Y, Zhang J
Annals of translational medicine 2019 Dec;7(24):797
Annals of translational medicine 2019 Dec;7(24):797
A self-organized actomyosin drives multiple intercellular junction disruption and directly promotes neutrophil recruitment in lipopolysaccharide-induced acute lung injury.
Chen B, Yang Z, Yang C, Qin W, Gu J, Hu C, Chen A, Ning J, Yi B, Lu K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun 7;:fj201701506RR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun 7;:fj201701506RR
Inhibiting transforming growth factor-β signaling regulates in vitro maintenance and differentiation of bovine bone marrow mesenchymal stem cells.
Zhao XX, An XL, Zhu XC, Jiang Y, Zhai YH, Zhang S, Cai NN, Tang B, Li ZY, Zhang XM
Journal of experimental zoology. Part B, Molecular and developmental evolution 2018 Dec;330(8):406-416
Journal of experimental zoology. Part B, Molecular and developmental evolution 2018 Dec;330(8):406-416
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia.
Leng YP, Ma YS, Li XG, Chen RF, Zeng PY, Li XH, Qiu CF, Li YP, Zhang Z, Chen AF
British journal of pharmacology 2018 Apr;175(8):1157-1172
British journal of pharmacology 2018 Apr;175(8):1157-1172
Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes.
Lu C, Xu W, Shao J, Zhang F, Chen A, Zheng S
Toxicological sciences : an official journal of the Society of Toxicology 2017 Feb;155(2):432-443
Toxicological sciences : an official journal of the Society of Toxicology 2017 Feb;155(2):432-443
A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.
Dai B, Wang W, Ma Y, Liu R, Zhang Y
Oncology reports 2016 Sep;36(3):1526-34
Oncology reports 2016 Sep;36(3):1526-34
Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway.
Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, Daa T, Iha H, Takahashi M, Nomura T, Sato F, Mimata H, Ikawa M, Seto M, Matsuura K, Moriyama M
The Journal of pathology 2016 May;239(1):97-108
The Journal of pathology 2016 May;239(1):97-108
Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation.
Lu C, Xu W, Zhang F, Shao J, Zheng S
Toxicology 2016 Jul 15;365:35-47
Toxicology 2016 Jul 15;365:35-47
Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress.
Muramatsu-Kato K, Itoh H, Kohmura-Kobayashi Y, Ferdous UJ, Tamura N, Yaguchi C, Uchida T, Suzuki K, Hashimoto K, Suganami T, Ogawa Y, Kanayama N
Scientific reports 2015 Nov 19;5:16867
Scientific reports 2015 Nov 19;5:16867
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 20103-1-AP( CD45 Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 20103-1-AP(CD45 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 20103-1-AP(CD45 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD45 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CD45. This antibody recognizes human, mouse antigen. The CD45 antibody has been validated for the following applications: ELISA, IHC, WB, FC analysis.