orb386014

antibody from Biorbyt
Targeting: CHGA
Provider product page for orb386014
Immunohistochemistry

Antibody data

Product number
orb386014 - Provider product page
Provider
Biorbyt
Product name
Chromogranin A Antibody
Antibody type
Polyclonal
Description
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of Chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Vial size
20 ug
Storage
Store the Chromogranin A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
CHGA protein structure - orb386014 shown in red.