BS1113

antibody from Bioworld Technology, Inc
Targeting: ESR1 ER-alpha, Era, ESR, NR3A1
Provider product page for BS1113
Western blot
Immunohistochemistry

Antibody data

Product number
BS1113 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1113, RRID:AB_1662976
Product name
ERÏ« (P98) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 61-110 of Human ERÏ«.
Description
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERÏ« and ERÉÇ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus , though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERÏ« and ERÉÇ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERÏ« and ERÉÇ may be regulated by distinct mechanisms even though they share many functional characteristics.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ESR1 protein structure - BS1113 shown in red.