Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS1535 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS1535, RRID:AB_1663720
- Product name
- ERÏ« (K531) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 501-550 of Human ERÏ«.
- Description
- Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor uperfamily of ligand-activated transcription factors. Estrogen receptors, ncluding ERÏ« and ERÉÇ, contain DNA binding and ligand binding domains nd are critically involved in regulating the normal function of reproductive issues. ERÏ« and ERÉÇ have been shown to be differentially activated by various igands. Receptor-ligand interactions trigger a cascade of events, including issociation from heat shock proteins, receptor dimerization, phosphorylation nd the association of the hormone activated receptor with specific regulatory lements in target genes. Evidence suggests that ERÏ« and ERÉÇ may be egulated by distinct mechanisms even though they share many functional characteristics.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ER¦Á (K531) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:sp2/0 whole cell lysateLane3:PC12 whole cell lysate