BS1535

antibody from Bioworld Technology, Inc
Targeting: ESR1 ER-alpha, Era, ESR, NR3A1
Provider product page for BS1535
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS1535 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1535, RRID:AB_1663720
Product name
ERÏ« (K531) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 501-550 of Human ERÏ«.
Description
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor uperfamily of ligand-activated transcription factors. Estrogen receptors, ncluding ERÏ« and ERÉÇ, contain DNA binding and ligand binding domains nd are critically involved in regulating the normal function of reproductive issues. ERÏ« and ERÉÇ have been shown to be differentially activated by various igands. Receptor-ligand interactions trigger a cascade of events, including issociation from heat shock proteins, receptor dimerization, phosphorylation nd the association of the hormone activated receptor with specific regulatory lements in target genes. Evidence suggests that ERÏ« and ERÉÇ may be egulated by distinct mechanisms even though they share many functional characteristics.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ESR1 protein structure - BS1535 shown in red.