Antibody data
- Antibody Data
- Antigen structure
- References [69]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 21244-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21244-1-AP, RRID:AB_11042600
- Product name
- ER antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ER antibody (Cat. #21244-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
Pan-Cancer Prognostic Role and Targeting Potential of the Estrogen-Progesterone Axis.
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1.
Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors.
Genistein reverses the effect of 17β-estradiol on exacerbating experimental occlusal interference-induced chronic masseter hyperalgesia in ovariectomised rats.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
The potential of Zishen Yutai pills to facilitate endometrial recovery and restore fertility after induced abortion in rats.
Weighted gene coexpression network analysis reveals ESR1, FLNA and Furin as hub genes for DEHP-induced prepubertal testicular injury.
The "Matrisome" reveals the characterization of skin keloid microenvironment.
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease.
Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.
InvivoPen: A novel plasma source for in vivo cancer treatment.
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Neuroprotective effects of vitamin D and 17ß-estradiol against ovariectomy-induced neuroinflammation and depressive-like state: Role of the AMPK/NF-κB pathway.
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Effect of liquiritin on neuroendocrine-immune network in menopausal rat model.
Natural flavonoid silibinin promotes the migration and myogenic differentiation of murine C2C12 myoblasts via modulation of ROS generation and down-regulation of estrogen receptor α expression.
The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study.
Targeting claudin-4 enhances chemosensitivity in breast cancer.
The ancient Chinese formula Longdan Xiegan Tang improves antipsychotic-induced hyperprolactinemia by repairing the hypothalamic and pituitary TGF-β1 signaling in rats.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
Elevated maternal androgen is associated with dysfunctional placenta and lipid disorder in newborns of mothers with polycystic ovary syndrome.
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner.
Vaccarin promotes proliferation of and milk synthesis in bovine mammary epithelial cells through the Prl receptor-PI3K signaling pathway.
The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A.
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
TP53 Mutations Promote Immunogenic Activity in Breast Cancer.
Dual targeting of estrogen receptor α and estrogen-related receptor α: a novel endocrine therapy for endometrial cancer.
Risk analysis of systemic levels of estrogen and adipokines as well as estrogen receptors from PBMCs in childbearing and perimenopausal women with obesity.
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha.
Oral exposure to low-dose bisphenol A induces hyperplasia of dorsolateral prostate and upregulates EGFR expression in adult Sprague-Dawley rats.
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus.
Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy.
Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ1-42 -induced reactive oxygen species/reactive nitrogen species generation.
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Estrogen nuclear receptors affect cell migration by altering sublocalization of AQP2 in glioma cell lines.
Rutin attenuates cerebral ischemia-reperfusion injury in ovariectomized rats via estrogen-receptor-mediated BDNF-TrkB and NGF-TrkA signaling.
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring.
Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity.
Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats.
EZH2 inhibition sensitizes tamoxifen‑resistant breast cancer cells through cell cycle regulation.
17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway.
HPK1 positive expression associated with longer overall survival in patients with estrogen receptor-positive invasive ductal carcinoma‑not otherwise specified.
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
MicroRNA-124 enhances response to radiotherapy in human epidermal growth factor receptor 2-positive breast cancer cells by targeting signal transducer and activator of transcription 3.
A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement.
miR-26b-3p Regulates Human Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation by Targeting Estrogen Receptor.
Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia.
Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.
ERβ up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells.
Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle.
Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.
ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells.
Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines.
MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention.
Zou J, Xu MX, Li F, Wang YH, Li XQ, Yu DJ, Ma YJ, Zhang YY, Sun XD
Thoracic cancer 2022 Jan;13(2):190-201
Thoracic cancer 2022 Jan;13(2):190-201
Pan-Cancer Prognostic Role and Targeting Potential of the Estrogen-Progesterone Axis.
Shen YT, Huang X, Zhang G, Jiang B, Li CJ, Wu ZS
Frontiers in oncology 2021;11:636365
Frontiers in oncology 2021;11:636365
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Zhang X, Cheng C, Zhang G, Xiao M, Li L, Wu S, Lu X
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Zhang H, Wu J, Li Y, Jin G, Tian Y, Kang S
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct 20;
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct 20;
Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1.
Khayeka-Wandabwa C, Zhao J, Pathak JL, Wu H, Bureik M
Breast cancer research and treatment 2021 Nov 1;
Breast cancer research and treatment 2021 Nov 1;
Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.
Tan J, Song C, Wang D, Hu Y, Liu D, Ma D, Gao Q
Bioscience reports 2021 May 28;41(5)
Bioscience reports 2021 May 28;41(5)
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Tang J, Wu Z, Tian Z, Chen W, Wu G
Cell death & disease 2021 May 25;12(6):534
Cell death & disease 2021 May 25;12(6):534
Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors.
Liu W, Wang F, Li C, Otkur W, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Onodera S, Ikejima T
Journal of photochemistry and photobiology. B, Biology 2021 Mar;216:112147
Journal of photochemistry and photobiology. B, Biology 2021 Mar;216:112147
Genistein reverses the effect of 17β-estradiol on exacerbating experimental occlusal interference-induced chronic masseter hyperalgesia in ovariectomised rats.
Liu Y, Zhang XY, Fan YY, Xu XX, Xie QF
Journal of oral rehabilitation 2021 Jun 2;
Journal of oral rehabilitation 2021 Jun 2;
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
The potential of Zishen Yutai pills to facilitate endometrial recovery and restore fertility after induced abortion in rats.
Li M, Ning N, Liu Y, Li X, Mei Q, Zhou J, Huang Q, Xiang W, Zhang L, Xu X
Pharmaceutical biology 2021 Dec;59(1):1505-1516
Pharmaceutical biology 2021 Dec;59(1):1505-1516
Weighted gene coexpression network analysis reveals ESR1, FLNA and Furin as hub genes for DEHP-induced prepubertal testicular injury.
Chen J, Kang L, Wang J, Wu Y, Han L, Zheng X, Wei Y, Zhao T, Shen L, Long C, Wei G, Wu S
Reproductive toxicology (Elmsford, N.Y.) 2021 Dec;106:115-125
Reproductive toxicology (Elmsford, N.Y.) 2021 Dec;106:115-125
The "Matrisome" reveals the characterization of skin keloid microenvironment.
Zhang S, Liu B, Wang W, Lv L, Gao D, Chai M, Li M, Wu Z, Zhu Y, Ma J, Leng L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21237
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21237
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
Guo S, Zhang B, Qi W, Cao X, Xu Y, Zhang X, Li X, Zhou L, Ye L
Toxicology 2021 Apr 15;453:152734
Toxicology 2021 Apr 15;453:152734
MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease.
Shao X, Li J, Xu F, Chen D, Liu K
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 2020;2020:8811477
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 2020;2020:8811477
Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.
Zheng D, Jiang C, Yan N, Miao Y, Wang K, Gao G, Jiao Y, Zhang X, He M, Yang Z
OncoTargets and therapy 2020;13:12649-12659
OncoTargets and therapy 2020;13:12649-12659
InvivoPen: A novel plasma source for in vivo cancer treatment.
Zhou X, Cai D, Xiao S, Ning M, Zhou R, Zhang S, Chen X, Ostrikov K, Dai X
Journal of Cancer 2020;11(8):2273-2282
Journal of Cancer 2020;11(8):2273-2282
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Mei Y, Cai D, Dai X
Journal of Cancer 2020;11(5):1162-1169
Journal of Cancer 2020;11(5):1162-1169
Neuroprotective effects of vitamin D and 17ß-estradiol against ovariectomy-induced neuroinflammation and depressive-like state: Role of the AMPK/NF-κB pathway.
Zhang WY, Guo YJ, Wang KY, Chen LM, Jiang P
International immunopharmacology 2020 Sep;86:106734
International immunopharmacology 2020 Sep;86:106734
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Tang J, Luo Y, Tian Z, Liao X, Cui Q, Yang Q, Wu G
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
Effect of liquiritin on neuroendocrine-immune network in menopausal rat model.
Lan XY, Yu H, Chen QJ, Zhai S, Zhang CF, Li F, Wang CZ, Yuan CS
Phytotherapy research : PTR 2020 Oct;34(10):2665-2674
Phytotherapy research : PTR 2020 Oct;34(10):2665-2674
Natural flavonoid silibinin promotes the migration and myogenic differentiation of murine C2C12 myoblasts via modulation of ROS generation and down-regulation of estrogen receptor α expression.
Long X, Gao Y, Liu W, Liu X, Hayashi T, Mizuno K, Hattori S, Ikejima T
Molecular and cellular biochemistry 2020 Nov;474(1-2):243-261
Molecular and cellular biochemistry 2020 Nov;474(1-2):243-261
The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study.
Chang LC, Chiang YF, Chen HY, Huang YJ, Liu AC, Hsia SM
Biomedicines 2020 Nov 22;8(11)
Biomedicines 2020 Nov 22;8(11)
Targeting claudin-4 enhances chemosensitivity in breast cancer.
Luo Y, Kishi S, Sasaki T, Ohmori H, Fujiwara-Tani R, Mori S, Goto K, Nishiguchi Y, Mori T, Kawahara I, Kondoh M, Kuniyasu H
Cancer science 2020 May;111(5):1840-1850
Cancer science 2020 May;111(5):1840-1850
The ancient Chinese formula Longdan Xiegan Tang improves antipsychotic-induced hyperprolactinemia by repairing the hypothalamic and pituitary TGF-β1 signaling in rats.
Ren L, Liu W, Wang C, Yang Y, Huang X, Wang C, Li Y
Journal of ethnopharmacology 2020 May 23;254:112572
Journal of ethnopharmacology 2020 May 23;254:112572
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.
Chu C, Gao X, Li X, Zhang X, Ma R, Jia Y, Li D, Wang D, Xu F
Biomolecules & therapeutics 2020 Mar 1;28(2):163-171
Biomolecules & therapeutics 2020 Mar 1;28(2):163-171
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
Chen GH, Zhang XL, Chen H, Lin H, Wu HJ, Lin H, Huang GZ
The journal of gene medicine 2020 Jun;22(6):e3174
The journal of gene medicine 2020 Jun;22(6):e3174
Elevated maternal androgen is associated with dysfunctional placenta and lipid disorder in newborns of mothers with polycystic ovary syndrome.
Sun M, Sun B, Qiao S, Feng X, Li Y, Zhang S, Lin Y, Hou L
Fertility and sterility 2020 Jun;113(6):1275-1285.e2
Fertility and sterility 2020 Jun;113(6):1275-1285.e2
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, Yuan C, Xu J, Yan L, Hao H
International immunopharmacology 2020 Aug;85:106625
International immunopharmacology 2020 Aug;85:106625
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner.
Jian L, Xie J, Guo S, Yu H, Chen R, Tao K, Yang C, Li K, Liu S
Oncology letters 2020 Aug;20(2):1441-1451
Oncology letters 2020 Aug;20(2):1441-1451
Vaccarin promotes proliferation of and milk synthesis in bovine mammary epithelial cells through the Prl receptor-PI3K signaling pathway.
Yu Y, Yuan X, Li P, Wang Y, Yu M, Gao X
European journal of pharmacology 2020 Aug 5;880:173190
European journal of pharmacology 2020 Aug 5;880:173190
The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A.
Wu S, Huang D, Su X, Yan H, Ma A, Li L, Wu J, Sun Z
Scientific reports 2020 Aug 4;10(1):13108
Scientific reports 2020 Aug 4;10(1):13108
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
Wang J, Zhang X, Zhang L, Yan T, Wu B, Xu F, Jia Y
European journal of pharmacology 2020 Aug 15;881:173236
European journal of pharmacology 2020 Aug 15;881:173236
TP53 Mutations Promote Immunogenic Activity in Breast Cancer.
Liu Z, Jiang Z, Gao Y, Wang L, Chen C, Wang X
Journal of oncology 2019;2019:5952836
Journal of oncology 2019;2019:5952836
Dual targeting of estrogen receptor α and estrogen-related receptor α: a novel endocrine therapy for endometrial cancer.
Mao X, Dong B, Gao M, Ruan G, Huang M, Braicu EI, Sehouli J, Sun P
OncoTargets and therapy 2019;12:6757-6767
OncoTargets and therapy 2019;12:6757-6767
Risk analysis of systemic levels of estrogen and adipokines as well as estrogen receptors from PBMCs in childbearing and perimenopausal women with obesity.
Fan H, Chen S, Gao B, Ding S, Zhao Q, Li C, Asakawa T
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1287-1295
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1287-1295
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
Dai X, Mei Y, Chen X, Cai D
Frontiers in genetics 2019;10:790
Frontiers in genetics 2019;10:790
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
Guo J, Wang Q, Zhang Y, Sun W, Zhang S, Li Y, Wang J, Bao Y
Pharmacological research 2019 Sep;147:104387
Pharmacological research 2019 Sep;147:104387
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Li H, Wu W, He X, Cao C, Yu X, Zeng Y, Li L
Bioscience reports 2019 Sep 30;39(9)
Bioscience reports 2019 Sep 30;39(9)
Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha.
Sun Y, Yang J, Liu W, Yao G, Xu F, Hayashi T, Onodera S, Ikejima T
Molecular and cellular biochemistry 2019 Oct;460(1-2):81-92
Molecular and cellular biochemistry 2019 Oct;460(1-2):81-92
Oral exposure to low-dose bisphenol A induces hyperplasia of dorsolateral prostate and upregulates EGFR expression in adult Sprague-Dawley rats.
Wu S, Huang D, Su X, Yan H, Wu J, Sun Z
Toxicology and industrial health 2019 Oct;35(10):647-659
Toxicology and industrial health 2019 Oct;35(10):647-659
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Ge L, Cui Y, Liu B, Yin X, Pang J, Han J
Molecular medicine reports 2019 May;19(5):3469-3476
Molecular medicine reports 2019 May;19(5):3469-3476
Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus.
Liu L, Yan J, Ge F, Xu X, Lu J, Shi H, Li S, Zhao Y, Zhang C
Molecular medicine reports 2019 Jul;20(1):332-340
Molecular medicine reports 2019 Jul;20(1):332-340
Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy.
Andrade FO, Nguyen NM, Warri A, Hilakivi-Clarke L
Scientific reports 2019 Dec 30;9(1):20271
Scientific reports 2019 Dec 30;9(1):20271
Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ1-42 -induced reactive oxygen species/reactive nitrogen species generation.
Yang J, Sun Y, Xu F, Liu W, Hayashi T, Hattori S, Ushiki-Kaku Y, Onodera S, Tashiro SI, Ikejima T
Phytotherapy research : PTR 2019 Apr;33(4):998-1009
Phytotherapy research : PTR 2019 Apr;33(4):998-1009
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Shen D, Tian L, Shen T, Sun H, Liu P
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Estrogen nuclear receptors affect cell migration by altering sublocalization of AQP2 in glioma cell lines.
Wan S, Jiang J, Zheng C, Wang N, Zhai X, Fei X, Wu R, Jiang X
Cell death discovery 2018;4:49
Cell death discovery 2018;4:49
Rutin attenuates cerebral ischemia-reperfusion injury in ovariectomized rats via estrogen-receptor-mediated BDNF-TrkB and NGF-TrkA signaling.
Liu H, Zhong L, Zhang Y, Liu X, Li J
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):672-681
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):672-681
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Ge L, Cui Y, Cheng K, Han J
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring.
Zhu J, Jia YL, Luo YW, Huang DY, Shao CC, Li L, Zhou L, Sun ZY
International urology and nephrology 2018 Nov;50(11):1963-1973
International urology and nephrology 2018 Nov;50(11):1963-1973
Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity.
Yang J, Sun Y, Xu F, Liu W, Hayashi T, Onodera S, Tashiro SI, Ikejima T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:344-353
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:344-353
Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats.
Huang DY, Zheng CC, Pan Q, Wu SS, Su X, Li L, Wu JH, Sun ZY
Scientific reports 2018 Jan 11;8(1):490
Scientific reports 2018 Jan 11;8(1):490
EZH2 inhibition sensitizes tamoxifen‑resistant breast cancer cells through cell cycle regulation.
Chen S, Yao F, Xiao Q, Liu Q, Yang Y, Li X, Jiang G, Kuno T, Fang Y
Molecular medicine reports 2018 Feb;17(2):2642-2650
Molecular medicine reports 2018 Feb;17(2):2642-2650
17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway.
Li P, Gan Y, Xu Y, Wang L, Ouyang B, Zhang C, Luo L, Zhao C, Zhou Q
International journal of biological sciences 2017;13(2):145-156
International journal of biological sciences 2017;13(2):145-156
HPK1 positive expression associated with longer overall survival in patients with estrogen receptor-positive invasive ductal carcinoma‑not otherwise specified.
Wang J, Song L, Yang S, Zhang W, Lu P, Li S, Li H, Wang L
Molecular medicine reports 2017 Oct;16(4):4634-4642
Molecular medicine reports 2017 Oct;16(4):4634-4642
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Fan S, Liao Y, Liu C, Huang Q, Liang H, Ai B, Fu S, Zhou S
Oncotarget 2017 Aug 22;8(34):56443-56459
Oncotarget 2017 Aug 22;8(34):56443-56459
MicroRNA-124 enhances response to radiotherapy in human epidermal growth factor receptor 2-positive breast cancer cells by targeting signal transducer and activator of transcription 3.
Fu Y, Xiong J
Croatian medical journal 2016 Oct 31;57(5):457-464
Croatian medical journal 2016 Oct 31;57(5):457-464
A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement.
Chen L, Lv D, Wang D, Chen X, Zhu Z, Cao Y, Chai Y
Molecular bioSystems 2016 Oct 18;12(11):3347-3356
Molecular bioSystems 2016 Oct 18;12(11):3347-3356
miR-26b-3p Regulates Human Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation by Targeting Estrogen Receptor.
Wang Q, Xu C, Zhao Y, Xu Z, Zhang Y, Jiang J, Yan B, Gu D, Wu M, Wang Y, Liu H
Stem cells and development 2016 Mar 1;25(5):415-26
Stem cells and development 2016 Mar 1;25(5):415-26
Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia.
Song L, Shen W, Zhang H, Wang Q, Wang Y, Zhou Z
Bosnian journal of basic medical sciences 2016 Jul 2;16(3):201-8
Bosnian journal of basic medical sciences 2016 Jul 2;16(3):201-8
Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.
Qin Z, Zheng H, Zhou L, Ou Y, Huang B, Yan B, Qin Z, Yang C, Su Y, Bai X, Guo J, Lin J
Scientific reports 2016 Jan 22;6:19587
Scientific reports 2016 Jan 22;6:19587
ERβ up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells.
Zheng N, Liu L, Liu W, Zhang P, Huang H, Zang L, Hayashi T, Tashiro S, Onodera S, Xia M, Ikejima T
Archives of biochemistry and biophysics 2016 Feb 1;591:141-9
Archives of biochemistry and biophysics 2016 Feb 1;591:141-9
Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle.
Ideta A, Yamashita S, Seki-Soma M, Yamaguchi R, Chiba S, Komaki H, Ito T, Konishi M, Aoyagi Y, Sendai Y
Scientific reports 2016 Apr 27;6:24983
Scientific reports 2016 Apr 27;6:24983
Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.
Fu C, Xu D, Wang CY, Jin Y, Liu Q, Meng Q, Liu KX, Sun HJ, Liu MZ
Journal of cellular physiology 2015 Sep;230(9):2184-201
Journal of cellular physiology 2015 Sep;230(9):2184-201
ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells.
Zheng N, Zhang P, Huang H, Liu W, Hayashi T, Zang L, Zhang Y, Liu L, Xia M, Tashiro S, Onodera S, Ikejima T
Journal of pharmacological sciences 2015 Jul;128(3):97-107
Journal of pharmacological sciences 2015 Jul;128(3):97-107
Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines.
Zhang C, Peng J, Wu S, Jin Y, Xia F, Wang C, Liu K, Sun H, Liu M
Journal of biomedical science 2014 Apr 17;21:30
Journal of biomedical science 2014 Apr 17;21:30
MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention.
Munagala R, Aqil F, Vadhanam MV, Gupta RC
Cancer letters 2013 Oct 10;339(2):175-84
Cancer letters 2013 Oct 10;339(2):175-84
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 21244-1-AP( ER Antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 21244-1-AP(ESR1 antibody) at dilution of 1:25 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ER antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ER. This antibody recognizes human,mouse,rat antigen. The ER antibody has been validated for the following applications: ELISA, IHC, WB analysis.