TAB-005

antibody from Creative Biolabs
Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL
Provider product page for TAB-005
No application information provided.

Antibody data

Product number
TAB-005 - Provider product page
Provider
Creative Biolabs
Product name
Anti-Human ErbB2 Recombinant Antibody (Trastuzumab)
Antibody type
Monoclonal
Description
Recombinant monoclonal antibody to Human ErbB2. Trastuzumab (INN; trade names Herclon, trastuzumab) is a monoclonal antibody that interferes with the HER2/neu receptor. Its main use is to treat certain breast cancers.The HER receptors are proteins that are embedded in the cell membrane and communicate molecular signals from outside the cell (molecules called EGFs) to inside the cell, and turn genes on and off. The HER proteins stimulate cell proliferation. In some cancers, notably certain types of breast cancer, HER2 is over-expressed, and causes cancer cells to reproduce uncontrollably.
Reactivity
Human
Storage
4¡ãC. For long term storage, aliquot and store at -20¡ãC. Repeated thawing and freezing must be avoided.
ERBB2 protein structure - TAB-005 shown in red.