10-7563-25

antibody from ABEOMICS Inc.
Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL
Provider product page for 10-7563-25

Antibody data

Product number
10-7563-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-c-erbB-2/Her2 Antibody
Antibody type
Monoclonal
Description
HER2, a known proto-oncogene, is located at the long arm of human chromosome 17 (17q12), encoding a type 1 tyrosine kinase growth factor receptor and the role of HER2 in the development of numerous types of human cancer. HER2 is a transmembrane receptor comprising an extracellular domain (ECD), a single transmembrane domain, and an intracellular domain (ICD) with tyrosine-kinase activity.The high-expression and amplification of C-erbB-2 and its protein products (P185) are found in a wide variety of tumors. HER2 is overexpressed in 10% to 35% of gastric and gastroesophageal junction (GEJ) adenocarcinomas.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A partial length protein (amino aci
ds 301-522) was used as the immunog
en for this antibody (from extra ce
llular domain of c-erbB-2).
Isotype
IgG
Antibody clone number
ABM45F5
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
ERBB2 protein structure - 10-7563-25 shown in red.