FNab00932

antibody from FineTest Biotech

Targeting: CTCFL BORIS, CT27, dJ579F20.2

Western blot

ELISA

Immunocytochemistry

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Validation data

Product number: FNab00932 - Provider product page
Provider: FineTest Biotech
Product name: BORIS antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
Reactivity: Human, Mouse
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: CCCTC-binding factor(zinc finger pr otein)-like
Epitope: IgG1
Isotype: IgG
Antibody clone number: 2B10
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CTCFL protein structure - FNab00932 shown in red.