NBP2-48129
antibody from Novus Biologicals
Targeting: TYRP1
b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- NBP2-48129 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TYRP1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 7 ml
- Storage
- Store at 4C.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry-Paraffin: TYRP1 Antibody (SPM611) - IHC-Prediluted [NBP2-48129] - Human Melanoma stained with TYRP1 monoclonal antibody (SPM611)