GTX30687

antibody from GeneTex

Targeting: NPC1 SLC65A1

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Immunoelectron microscopy (Data presented on provider website)

Antibody Data

Product number

GTX30687

Provider

GeneTex

Proper citation

GeneTex Cat#GTX30687, RRID:AB_625985

Product name

NPC1 antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat, Hamster, Porcine, Simian

Host

Rabbit

References

Submitted references

Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.

Frolov A, Srivastava K, Daphna-Iken D, Traub LM, Schaffer JE, Ory DS
The Journal of biological chemistry 2001 Dec 7;276(49):46414-21

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Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis.

Millard EE, Srivastava K, Traub LM, Schaffer JE, Ory DS
The Journal of biological chemistry 2000 Dec 8;275(49):38445-51

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Western Blot: Niemann-Pick C1 Antibody [GTX30687] - Detection of human NPC1 in 20 μg of human fibroblast cell lysate.

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Niemann-Pick C1 Antibody [GTX30687] - Staining of human brain, cortex, neurons and astrocytes.