APR03462G

antibody from Leading Biology

Targeting: C2

Western blot

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Validation data

Product number: APR03462G - Provider product page
Provider: Leading Biology
Product name: C2 Antibody (N-term)
Antibody type: Polyclonal
Description: Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. ActivatedC1 cleaves C2 into C2a and C2b. The serine proteinase C2a thencombines with complement factor 4b to create the C3 or C5convertase. Deficiency of C2 has been reported to associated withcertain autoimmune diseases and SNPs in this gene have beenassociated with altered susceptibility to age-related maculardegeneration. This gene localizes within the class III region ofthe MHC on the short arm of chromosome 6. Alternative splicingresults in multiple transcript variants encoding distinct isoforms.Additional transcript variants have been described in publicationsbut their full-length sequence has not been determined.
Reactivity: Human, Hamster
Host: Rabbit
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

C2 protein structure - APR03462G shown in red.