orb1716277

antibody from Biorbyt
Targeting: DCN DSPG2, SLRR1B
Provider product page for orb1716277
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb1716277 - Provider product page
Provider
Biorbyt
Product name
Decorin Antibody
Antibody type
Monoclonal
Description
Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
DCN/6289
Vial size
100 μg
Storage
Aliquot the Decorin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
DCN protein structure - orb1716277 shown in red.