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- References [709]
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- Product number
- 18420-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18420-1-AP, RRID:AB_10694431
- Product name
- P62,SQSTM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated P62,SQSTM1 antibody (Cat. #18420-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense.
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma.
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
Imiquimod induced vitiligo-like lesions-A consequence of modified melanocyte function.
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxide via the Stimulation of Autophagy.
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration.
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
TFE3 Regulates the Function of the Autophagy-Lysosome Pathway to Drive the Invasion and Metastasis of Papillary Thyroid Carcinoma.
Exercise combined with trimetazidine improves anti-fatal stress capacity through enhancing autophagy and heat shock protein 70 of myocardium in mice.
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
SC75741, A Novel c-Abl Inhibitor, Promotes the Clearance of TDP25 Aggregates via ATG5-Dependent Autophagy Pathway.
Autophagy Induced by the N-Terminus of the Classic Swine Fever Virus Nonstructural Protein 5A Protein Promotes Viral Replication.
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
The Clinicopathological Distinction Between Seropositive and Seronegative Immune-Mediated Necrotizing Myopathy in China.
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway.
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway.
Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway.
Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells.
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway.
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Delivering progranulin to neuronal lysosomes protects against excitotoxicity.
Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
Tau N-Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model.
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Chronic Restraint Stress-Induced Muscle Atrophy Leads to Fatigue in Mice by Inhibiting the AMPK Signaling Pathway.
Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway.
7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson's disease.
METTL3-m6A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.
Fasting improves tolerance to acute hypoxia in rats.
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Autophagy was activated against the damages of placentas caused by nano-copper oral exposure.
Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p.
l-cysteine-modified chiral gold nanoparticles promote periodontal tissue regeneration.
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
Bergenin attenuates bleomycin-induced pulmonary fibrosis in mice via inhibiting TGF-β1 signaling pathway.
USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy.
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery.
Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair.
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Autophagy deficiency activates rDNA transcription.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Extracellular IL-37 promotes osteogenic and odontogenic differentiation of human dental pulp stem cells via autophagy.
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Overexpression of HIF-1α enhances the protective effect of mitophagy on steroid-induced osteocytes apoptosis.
eIF2A-knockout mice reveal decreased life span and metabolic syndrome.
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E2 Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
17β-estradiol improves the developmental ability, inhibits reactive oxygen species levels and apoptosis of porcine oocytes by regulating autophagy events.
Acetylation of STX17 (syntaxin 17) controls autophagosome maturation.
Biosynthetic gold nanoparticles of Hibiscus syriacus L. callus potentiates anti-inflammation efficacy via an autophagy-dependent mechanism.
Proteomic analysis of aged and OPTN E50K retina in the development of normal tension glaucoma.
Nuclear receptor coactivator 4-mediated ferritinophagy drives proliferation of dental pulp stem cells in hypoxia.
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Interfering with hyaluronic acid metabolism suppresses glioma cell proliferation by regulating autophagy.
Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection.
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Lactobacillus salivarius ameliorated Mycoplasma gallisepticum-induced inflammatory injury and secondary Escherichia coli infection in chickens: Involvement of intestinal microbiota.
Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway.
CXXC5 orchestrates Stat3/Erk/Akt signaling networks to modulate P. gingivalis-elicited autophagy in cementoblasts.
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Hongjingtian injection protects against myocardial ischemia reperfusion-induced apoptosis by blocking ROS induced autophagic- flux.
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b.
Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory Actions.
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca2+/CaMKII signal pathway.
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension.
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis.
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice.
Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
Autophagy inhibition and microRNA‑199a‑5p upregulation in paclitaxel‑resistant A549/T lung cancer cells.
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Activated autophagy restored the impaired frequency and function of regulatory T cells in chronic prostatitis.
The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury.
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Srag Regulates Autophagy via Integrating into a Preexisting Autophagy Pathway in Testis.
Salidroside inhibits apoptosis and autophagy of cardiomyocyte by regulation of circular RNA hsa_circ_0000064 in cardiac ischemia-reperfusion injury.
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation.
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation.
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Atmospheric PM2.5 blocking up autophagic flux in HUVECs via inhibiting Sntaxin-17 and LAMP2.
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome.
Autophagy Induction Contributes to the Neuroprotective Impact of Intermittent Fasting on the Acutely Injured Spinal Cord.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells.
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy.
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Regorafenib-Attenuated, Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway.
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway.
ZFP91 is required for the maintenance of regulatory T cell homeostasis and function.
The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A.
The abrupt pathological deterioration of cisplatin-induced acute kidney injury: Emerging of a critical time point.
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Goose nephritic astrovirus infection increases autophagy, destroys intercellular junctions in renal tubular epithelial cells, and damages podocytes in the kidneys of infected goslings.
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle.
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
The unique Akt inhibitor SC66 suppressed AMPK activity and abolished autophagy through the EGFR-p62 pathway.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pulmonary Exposure to Copper Oxide Nanoparticles Leads to Neurotoxicity via Oxidative Damage and Mitochondrial Dysfunction.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Biosynthesis of gold nanoparticles using Nigella sativa and Curtobacterium proimmune K3 and evaluation of their anticancer activity.
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Adenovirus Remodeling of the Host Proteome and Host Factors Associated with Viral Genomes.
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice.
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
PINK1/Parkin-mediated mitophagy inhibits warangalone-induced mitochondrial apoptosis in breast cancer cells.
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
LC3B/p62-mediated mitophagy protects A549 cells from resveratrol-induced apoptosis.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Anti-glioblastoma Activity of Kaempferol via Programmed Cell Death Induction: Involvement of Autophagy and Pyroptosis.
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
NDUFA4L2 Regulated by HIF-1α Promotes Metastasis and Epithelial-Mesenchymal Transition of Osteosarcoma Cells Through Inhibiting ROS Production.
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
4-Acetylantrocamol LT3, a New Ubiquinone from Antrodia cinnamomea, Inhibits Hepatocellular Carcinoma HepG2 Cell Growth by Targeting YAP/TAZ, mTOR, and WNT/β-Catenin Signaling.
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
Yi-Zhi-Fang-Dai Formula Exerts a Protective Effect on the Injury of Tight Junction Scaffold Proteins in Vitro and in Vivo by Mediating Autophagy through Regulation of the RAGE/CaMKKβ/AMPK/mTOR Pathway.
Protective Role of Coenzyme Q10 in Acute Sepsis-Induced Liver Injury in BALB/c Mice.
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.
Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway.
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice.
RAB37 multiple alleles, transcription activation and evolution in mammals.
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Gallbladder Cancer Progression Is Reversed by Nanomaterial-Induced Photothermal Therapy in Combination with Chemotherapy and Autophagy Inhibition.
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis.
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation.
Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells.
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Poly C Binding Protein 1 Regulates p62/SQSTM1 mRNA Stability and Autophagic Degradation to Repress Tumor Progression.
Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy.
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux.
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
The Effect of Autophagy on Chronic Intermittent Hypobaric Hypoxia Ameliorating Liver Damage in Metabolic Syndrome Rats.
NLRC5 Inhibits Inflammation of Secretory Phase Ectopic Endometrial Stromal Cells by Up-Regulating Autophagy in Ovarian Endometriosis.
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
PIWI-Interacting RNA-004800 Is Regulated by S1P Receptor Signaling Pathway to Keep Myeloma Cell Survival.
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
FTO accelerates ovarian cancer cell growth by promoting proliferation, inhibiting apoptosis, and activating autophagy.
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo.
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy.
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Cellular evidence of autophagy in Sertoli cells during spermatogenesis in goats.
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Activated FMS-like tyrosine kinase 3 ameliorates angiotensin II-induced cardiac remodelling.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma.
Phosphorylation of PRAS40 contributes to the activation of the PI3K/AKT/mTOR signaling pathway and the inhibition of autophagy following status epilepticus in rats.
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein.
Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation.
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
Past Exposure to Cigarette Smoke Aggravates Cognitive Impairment in a Rat Model of Vascular Dementia via Neuroinflammation.
CdSe/ZnS quantum dots induced spermatogenesis dysfunction via autophagy activation.
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells.
Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway.
NPRL2 promotes docetaxel chemoresistance in castration resistant prostate cancer cells by regulating autophagy through the mTOR pathway.
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Impairment of Proteasome and Autophagy Underlying the Pathogenesis of Leukodystrophy.
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Autophagy in endothelial cells regulates their haematopoiesis-supporting ability.
Autophagic-CTSB-inflammasome axis modulates hepatic stellate cells activation in arsenic-induced liver fibrosis.
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
ChREBP-β regulates thermogenesis in brown adipose tissue.
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
The in vitro effects of phospholipase D1-mTOR axis in liver fibrogenesis.
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Siderophores induce mitophagy-dependent apoptosis in platelets.
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS.
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway.
Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy.
Dehydroandrographolide inhibits mastitis by activating autophagy without affecting intestinal flora.
Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses.
PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.
N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells.
Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
A robust TDP-43 knock-in mouse model of ALS.
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina.
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures.
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy.
Nobiletin Triggers Reactive Oxygen Species-Mediated Pyroptosis through Regulating Autophagy in Ovarian Cancer Cells.
Heterogeneous Responses of Gastric Cancer Cell Lines to Tenovin-6 and Synergistic Effect with Chloroquine.
Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34.
Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.
Treadmill exercise improves neurological function by inhibiting autophagy and the binding of HMGB1 to Beclin1 in MCAO juvenile rats.
MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Disruption of the Keap1/Nrf2-Antioxidant Response System After Chronic Doxorubicin Exposure In Vivo.
Identification of curcumin as a novel natural inhibitor of rDNA transcription.
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis.
Potential therapeutic role of fibroblast growth factor 21 in neurodegeneration: Evidence for ameliorating parkinsonism via silent information regulator 2 homolog 1 and implication for gene therapy.
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway.
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways.
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux.
Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.
Artemisinin Attenuated Atherosclerosis in High-Fat Diet-Fed ApoE-/- Mice by Promoting Macrophage Autophagy Through the AMPK/mTOR/ULK1 Pathway.
Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases.
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
LncRNA expression profile during autophagy and Malat1 function in macrophages.
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress.
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Apigenin Combined With Gefitinib Blocks Autophagy Flux and Induces Apoptotic Cell Death Through Inhibition of HIF-1α, c-Myc, p-EGFR, and Glucose Metabolism in EGFR L858R+T790M-Mutated H1975 Cells.
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate ameliorates pressure overload-induced cardiac hypertrophy and dysfunction through inhibiting autophagy.
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
Protective role of thymoquinone in sepsis-induced liver injury in BALB/c mice.
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine.
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity.
Krüppel‑like factor 4 ameliorates diabetic kidney disease by activating autophagy via the mTOR pathway.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome.
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells.
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma.
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Mitophagy protects against statin-mediated skeletal muscle toxicity.
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Dihydroartemisinin, an antimalarial drug, induces absent in melanoma 2 inflammasome activation and autophagy in human hepatocellular carcinoma HepG2215 cells.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy.
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Carfilzomib enhances cisplatin-induced apoptosis in SK-N-BE(2)-M17 human neuroblastoma cells.
Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte.
LncRNA ENST00000453774.1 contributes to oxidative stress defense dependent on autophagy mediation to reduce extracellular matrix and alleviate renal fibrosis.
miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis.
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
SQSTM1/p62 loss reverses the inhibitory effect of sunitinib on autophagy independent of AMPK signaling.
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
iRoot BP Plus promotes osteo/odontogenic differentiation of bone marrow mesenchymal stem cells via MAPK pathways and autophagy.
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
ERβ promotes Aβ degradation via the modulation of autophagy.
Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.
Berberine ameliorates oxidative stress-induced apoptosis by modulating ER stress and autophagy in human nucleus pulposus cells.
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
Alterations of autophagy in knee cartilage by treatment with treadmill exercise in a rat osteoarthritis model.
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells.
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Autophagy protects against redox-active trace metal-induced cell death in rabbit synovial fibroblasts through Toll-like receptor 4 activation.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Taurine protected As2O3-induced the activation of hepatic stellate cells through inhibiting PPARα-autophagy pathway.
Anti-Invasion and Antiangiogenic Effects of Stellettin B through Inhibition of the Akt/Girdin Signaling Pathway and VEGF in Glioblastoma Cells.
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Loss of HMBOX1 promotes LPS-induced apoptosis and inhibits LPS-induced autophagy of vascular endothelial cells in mouse.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
FAM134B improves preadipocytes differentiation by enhancing mitophagy.
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition.
Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells.
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress.
A New Possible Mechanism by Which Punicalagin Protects against Liver Injury Induced by Type 2 Diabetes Mellitus: Upregulation of Autophagy via the Akt/FoxO3a Signaling Pathway.
Solanesol derived therapeutic carriers for anticancer drug delivery.
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Zearalenone induces NLRP3-dependent pyroptosis via activation of NF-κB modulated by autophagy in INS-1 cells.
Quercetin shows anti-tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway.
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function.
Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice.
TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ.
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease.
Taurine improves low-level inorganic arsenic-induced insulin resistance by activating PPARγ-mTORC2 signalling and inhibiting hepatic autophagy.
Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
The regulatory role of COX-2 in the interaction between Cr(VI)-induced endoplasmic reticulum stress and autophagy in DF-1 cells.
Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway.
Activation of Cyclooxygenase-2 by ATF4 During Endoplasmic Reticulum Stress Regulates Kidney Podocyte Autophagy Induced by Lupus Nephritis.
3-methyadenine attenuates chloroform-induced hepatotoxicity via autophagy activation.
Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia.
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis.
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Comprehensive anti-tumor effect of Brusatol through inhibition of cell viability and promotion of apoptosis caused by autophagy via the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.
Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation.
NLRC5 and autophagy combined as possible predictors in patients with endometriosis.
mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Mutant UBQLN2P497H in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury.
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites.
Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells.
Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion.
A novel stromal lncRNA signature reprograms fibroblasts to promote the growth of oral squamous cell carcinoma via LncRNA-CAF/interleukin-33.
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.
Prodigiosin stimulates endoplasmic reticulum stress and induces autophagic cell death in glioblastoma cells.
A tumor-activatable particle with antimetastatic potential in breast cancer via inhibiting the autophagy-dependent disassembly of focal adhesion.
Association of HMGB1, BRCA1 and P62 expression in ovarian cancer and chemotherapy sensitivity.
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Potentiating bacterial cancer therapy using hydroxychloroquine liposomes.
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Tripterygium glycoside protects against puromycin amino nucleoside‑induced podocyte injury by upregulating autophagy.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
p38δ MAPK regulates aggresome biogenesis by phosphorylating SQSTM1 in response to proteasomal stress.
Effects of n-3PUFAs on autophagy and inflammation of hypothalamus and body weight in mice.
Chronic intermittent hypobaric hypoxia protects vascular endothelium by ameliorating autophagy in metabolic syndrome rats.
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
Pancreatic islet-autonomous effect of arsenic on insulin secretion through endoplasmic reticulum stress-autophagy pathway.
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Autophagy dysregulation caused by ApoM deficiency plays an important role in liver lipid metabolic disorder.
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells.
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells.
LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation.
Pre-treatment with angiotensin-(1-7) inhibits tumor growth via autophagy by downregulating PI3K/Akt/mTOR signaling in human nasopharyngeal carcinoma xenografts.
Autophagy participates in innate immune defense in lamprey.
FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
O-GlcNAc-modified SNAP29 inhibits autophagy-mediated degradation via the disturbed SNAP29-STX17-VAMP8 complex and exacerbates myocardial injury in type I diabetic rats.
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration.
Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice.
Attenuating Spinal Cord Injury by Conditioned Medium from Bone Marrow Mesenchymal Stem Cells.
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Inhibition of acetaminophen-induced hepatotoxicity in mice by exogenous thymosinβ4 treatment.
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
(-)-Guaiol regulates autophagic cell death depending on mTOR signaling in NSCLC.
HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.
Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease.
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis.
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway.
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction.
VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy.
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
HMGA2 plays an important role in Cr (VI)-induced autophagy.
The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.
Mono-(2-ethylhexyl) phthalate induced ROS-dependent autophagic cell death in human vascular endothelial cells.
An autophagic mechanism is involved in the 6-hydroxydopamine-induced neurotoxicity in vivo.
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.
mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis.
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Prion-like transmission of α-synuclein pathology in the context of an NFL null background.
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Synergism and mechanism of Astragaloside IV combined with Ginsenoside Rg1 against autophagic injury of PC12 cells induced by oxygen glucose deprivation/reoxygenation.
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.
miR-29b contributes to multiple types of muscle atrophy.
BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis.
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells.
Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway.
The PI3K/Akt/mTOR pathway is involved in CVB3-induced autophagy of HeLa cells.
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.
Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils.
Propylene Glycol Alginate Sodium Sulfate Alleviates Cerulein-Induced Acute Pancreatitis by Modulating the MEK/ERK Pathway in Mice.
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course.
Comparison of the in vivo induction and transmission of α-synuclein pathology by mutant α-synuclein fibril seeds in transgenic mice.
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1.
Systematic Characterization of Autophagy in Gestational Diabetes Mellitus.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.
Regulation of Autophagy-Related Protein and Cell Differentiation by High Mobility Group Box 1 Protein in Adipocytes.
Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment.
Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages.
Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition.
Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy.
Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.
Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin.
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Egr-1 promotes hypoxia-induced autophagy to enhance chemo-resistance of hepatocellular carcinoma cells.
Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells.
β-asarone improves learning and memory and reduces Acetyl Cholinesterase and Beta-amyloid 42 levels in APP/PS1 transgenic mice by regulating Beclin-1-dependent autophagy.
Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus.
TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy.
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.
Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat chloride-induced hypoxia.
Autophagy protects renal tubular cells against ischemia / reperfusion injury in a time-dependent manner.
Chloroquine-enhanced efficacy of cisplatin in the treatment of hypopharyngeal carcinoma in xenograft mice.
Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy.
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Citreoviridin induces ROS-dependent autophagic cell death in human liver HepG2 cells.
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice.
Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice.
A novel antitumour strategy using bidirectional autophagic vesicles accumulation via initiative induction and the terminal restraint of autophagic flux.
Induction of autophagy improves embryo viability in cloned mouse embryos.
Identification and quantitative analysis of cellular proteins affected by treatment with withaferin a using a SILAC-based proteomics approach.
Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease.
SQSTM1 splice site mutation in distal myopathy with rimmed vacuoles.
Knockdown of autophagy-related gene LC3 enhances the sensitivity of HepG2 cells to epirubicin.
Targeted sequencing and identification of genetic variants in sporadic inclusion body myositis.
Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma.
Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker.
A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease.
Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells.
Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently.
mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein.
Wang Y, Wang L, Wang X, Cheng G, Xing Y, Zhang M, Zhang P, Liu J
Biological trace element research 2022 Mar;200(3):1312-1320
Biological trace element research 2022 Mar;200(3):1312-1320
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Jiang Y, Li H, Huang P, Li S, Li B, Huo L, Zhong J, Pan Z, Li Y, Xia X
Journal of ethnopharmacology 2022 Mar 1;285:114859
Journal of ethnopharmacology 2022 Mar 1;285:114859
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense.
Xie W, Jin S, Zhang C, Yang S, Wu Y, Zhao Y, Songyang Z, Cui J
Cell death and differentiation 2022 Jan;29(1):40-53
Cell death and differentiation 2022 Jan;29(1):40-53
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma.
Xu Q, Zhang H, Liu H, Han Y, Qiu W, Li Z
Biomaterials 2022 Jan;280:121287
Biomaterials 2022 Jan;280:121287
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Jia S, He D, Liang X, Cheng P, Liu J, Chen M, Wang C, Zhang H, Meng C
Molecular medicine reports 2022 Jan;25(1)
Molecular medicine reports 2022 Jan;25(1)
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Ma C, Wu H, Yang G, Xiang J, Feng K, Zhang J, Hua Y, Kang L, Fan G, Yang S
British journal of pharmacology 2022 Jan;179(2):252-269
British journal of pharmacology 2022 Jan;179(2):252-269
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Zhong Y, Luo R, Liu Q, Zhu J, Lei M, Liang X, Wang X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
He Y, Wang W, Xu X, Yang B, Yu X, Wu Y, Wang J
Bone 2022 Jan;154:116182
Bone 2022 Jan;154:116182
Imiquimod induced vitiligo-like lesions-A consequence of modified melanocyte function.
Yu H, Cen J, Lin X, Cheng H, Seifert O
Immunity, inflammation and disease 2022 Jan;10(1):70-77
Immunity, inflammation and disease 2022 Jan;10(1):70-77
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Li S, Ma Y, Ye S, Hu D, Xiao F
Journal of hazardous materials 2022 Jan 5;421:126758
Journal of hazardous materials 2022 Jan 5;421:126758
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Xi H, Ren F, Li Y, Xian M, Wang L, Hu J
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Wang Y, He M, Li X, Chai J, Jiang Q, Peng C, He G, Huang W
Frontiers in chemistry 2021;9:700956
Frontiers in chemistry 2021;9:700956
Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxide via the Stimulation of Autophagy.
Li S, Jiang Y, Xing X, Lin R, Li Q, Zhou W, Qiu W, Zheng W
Oxidative medicine and cellular longevity 2021;2021:7654143
Oxidative medicine and cellular longevity 2021;2021:7654143
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
Ruan D, Deng S, Liu Z, He J
BioMed research international 2021;2021:6698366
BioMed research international 2021;2021:6698366
Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration.
Hu S, Zhang C, Qian T, Bai Y, Chen L, Chen J, Huang C, Xie C, Wang X, Jin H
Oxidative medicine and cellular longevity 2021;2021:6694964
Oxidative medicine and cellular longevity 2021;2021:6694964
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
Zhao R, Wang B, Wang D, Wu B, Ji P, Tan D
Oxidative medicine and cellular longevity 2021;2021:6675264
Oxidative medicine and cellular longevity 2021;2021:6675264
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Zhang J, Cheng P, Dai W, Ji J, Wu L, Feng J, Wu J, Yu Q, Li J, Guo C
PPAR research 2021;2021:6658944
PPAR research 2021;2021:6658944
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Zhao J, Lan W, Peng J, Guan B, Liu J, Zhang M, Zhan Z, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
TFE3 Regulates the Function of the Autophagy-Lysosome Pathway to Drive the Invasion and Metastasis of Papillary Thyroid Carcinoma.
Lu H, Zhu C, Ruan Y, Fan L, Wei K, Yang Z, Chen Q
Analytical cellular pathology (Amsterdam) 2021;2021:3081491
Analytical cellular pathology (Amsterdam) 2021;2021:3081491
Exercise combined with trimetazidine improves anti-fatal stress capacity through enhancing autophagy and heat shock protein 70 of myocardium in mice.
Jiang L, Shen X, Dun Y, Xie M, Fu S, Zhang W, Qiu L, Ripley-Gonzalez JW, Liu S
International journal of medical sciences 2021;18(7):1680-1686
International journal of medical sciences 2021;18(7):1680-1686
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
Xing Y, Zhang M, Wang MM, Feng YS, Dong F, Zhang F
Frontiers in cellular neuroscience 2021;15:633280
Frontiers in cellular neuroscience 2021;15:633280
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Chen X, Yang K, Jin X, Meng Z, Liu B, Yu H, Lu P, Wang K, Fan Z, Tang Z, Zhang F, Liu C
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72
American journal of translational research 2021;13(1):57-72
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
Xiong M, Hu W, Tan Y, Yu H, Zhang Q, Zhao C, Yi Y, Wang Y, Wu Y, Wu M
Frontiers in physiology 2021;12:748040
Frontiers in physiology 2021;12:748040
SC75741, A Novel c-Abl Inhibitor, Promotes the Clearance of TDP25 Aggregates via ATG5-Dependent Autophagy Pathway.
Zhou D, Yan H, Yang S, Zhang Y, Xu X, Cen X, Lei K, Xia H
Frontiers in pharmacology 2021;12:741219
Frontiers in pharmacology 2021;12:741219
Autophagy Induced by the N-Terminus of the Classic Swine Fever Virus Nonstructural Protein 5A Protein Promotes Viral Replication.
Zhang C, Wang X, Sun J, Guo M, Zhang X, Wu Y
Frontiers in microbiology 2021;12:733385
Frontiers in microbiology 2021;12:733385
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589
Frontiers in pharmacology 2021;12:676589
The Clinicopathological Distinction Between Seropositive and Seronegative Immune-Mediated Necrotizing Myopathy in China.
Ma X, Xu L, Ji S, Li Y, Bu B
Frontiers in neurology 2021;12:670784
Frontiers in neurology 2021;12:670784
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Liao M, Wang C, Yang B, Huang D, Zheng Y, Wang S, Wang X, Zhang J, Tang C, Xu Z, He Y, Huang R, Zhang F, Wang Z, Wang N
Frontiers in pharmacology 2021;12:659297
Frontiers in pharmacology 2021;12:659297
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055
Frontiers in physiology 2021;12:650055
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wei W, Lu M, Lan XB, Liu N, Su WK, Dushkin AV, Yu JQ
Frontiers in pharmacology 2021;12:642415
Frontiers in pharmacology 2021;12:642415
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ji W, Wan T, Zhang F, Zhu X, Guo S, Mei X
Frontiers in pharmacology 2021;12:641058
Frontiers in pharmacology 2021;12:641058
Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway.
Li X, Huang K, Liu X, Ruan H, Ma L, Liang J, Cui Y, Wang Y, Wu S, Li H, Wei Y, Li Z, Gao J, Yang B, Li X, Yang G, Zhou H, Yang C
Frontiers in pharmacology 2021;12:639574
Frontiers in pharmacology 2021;12:639574
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Su J, Gao C, Xie L, Fan Y, Shen Y, Huang Q, Wang N, Xu Y, Yang N, Gui D
Frontiers in pharmacology 2021;12:638422
Frontiers in pharmacology 2021;12:638422
Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway.
Li L, Li Q, Huang W, Han Y, Tan H, An M, Xiang Q, Zhou R, Yang L, Cheng Y
Frontiers in pharmacology 2021;12:589273
Frontiers in pharmacology 2021;12:589273
Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway.
Dai H, Ma B, Dai X, Pang J, Wang J, Zhao Y, Wang M, Zhang H, Gao H, Qian S, Tian F, Sun X
Frontiers in pharmacology 2021;12:585286
Frontiers in pharmacology 2021;12:585286
Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells.
Liu X, Wang S, Zheng H, Liu Q, Shen T, Wang X, Ren D
American journal of cancer research 2021;11(7):3496-3514
American journal of cancer research 2021;11(7):3496-3514
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
Ning H, Zhang W, Kang J, Ding T, Liang X, Lu Y, Guo C, Sun W, Wang H, Bai Y, Shen L
Frontiers in cellular and infection microbiology 2021;11:647220
Frontiers in cellular and infection microbiology 2021;11:647220
Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway.
Liu Q, Zheng B, Zhang Y, Huang W, Hong Q, Meng Y
Canadian journal of physiology and pharmacology 2021 Sep;99(9):885-893
Canadian journal of physiology and pharmacology 2021 Sep;99(9):885-893
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Yang B, Peng F, Zhang Y, Wang X, Wang S, Zheng Y, Zhang J, Zeng Y, Wang N, Peng C, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Yang Y, Tian J, Zhang H, Ma M, Li H, Liu T, Yang Y, Liu T, She R
Virus research 2021 Sep;302:198369
Virus research 2021 Sep;302:198369
Delivering progranulin to neuronal lysosomes protects against excitotoxicity.
Davis SE, Roth JR, Aljabi Q, Hakim AR, Savell KE, Day JJ, Arrant AE
The Journal of biological chemistry 2021 Sep;297(3):100993
The Journal of biological chemistry 2021 Sep;297(3):100993
Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
Meng L, Goto M, Tanaka H, Kamikokura Y, Fujii Y, Okada Y, Furukawa H, Nishikawa Y
The American journal of pathology 2021 Sep;191(9):1580-1591
The American journal of pathology 2021 Sep;191(9):1580-1591
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
Wang C, Qu L, Li S, Yin F, Ji L, Peng W, Luo H, Lu D, Liu X, Chen X, Kong L, Wang X
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
Tau N-Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model.
Wu C, Zhao J, Wu Q, Tan Q, Liu Q, Xiao S
International journal of molecular sciences 2021 Sep 8;22(18)
International journal of molecular sciences 2021 Sep 8;22(18)
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, Lundberg K, Adams DJ, Qi X
Nature communications 2021 Sep 6;12(1):5305
Nature communications 2021 Sep 6;12(1):5305
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Li W, Li W, Wang Y, Leng Y, Xia Z
Cell death discovery 2021 Sep 29;7(1):267
Cell death discovery 2021 Sep 29;7(1):267
Chronic Restraint Stress-Induced Muscle Atrophy Leads to Fatigue in Mice by Inhibiting the AMPK Signaling Pathway.
Wang Z, Xia T, Jin S, Liu X, Pan R, Yan M, Chang Q
Biomedicines 2021 Sep 26;9(10)
Biomedicines 2021 Sep 26;9(10)
Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway.
Lu H, Jia C, Wu D, Jin H, Lin Z, Pan J, Li X, Wang W
Cell death & disease 2021 Sep 23;12(10):865
Cell death & disease 2021 Sep 23;12(10):865
7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson's disease.
Zuo L, Dai C, Yi L, Dong Z
Cell death discovery 2021 Sep 20;7(1):254
Cell death discovery 2021 Sep 20;7(1):254
METTL3-m6A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Peng Z, Gong Y, Wang X, He W, Wu L, Zhang L, Xiong L, Huang Y, Su L, Shi P, Cao X, Liu R, Li Y, Xiao H
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Sep 20;
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Sep 20;
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q
Aging 2021 Sep 14;13(17):21202-21215
Aging 2021 Sep 14;13(17):21202-21215
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.
Read ML, Brookes K, Thornton CEM, Fletcher A, Nieto HR, Alshahrani M, Khan R, Borges de Souza P, Zha L, Webster JRM, Alderwick LJ, Campbell MJ, Boelaert K, Smith VE, McCabe CJ
Cell chemical biology 2021 Sep 11;
Cell chemical biology 2021 Sep 11;
Fasting improves tolerance to acute hypoxia in rats.
Yue XY, Wang XB, Zhao RZ, Jiang S, Zhou X, Jiao B, Zhang L, Yu ZB
Biochemical and biophysical research communications 2021 Sep 10;569:161-166
Biochemical and biophysical research communications 2021 Sep 10;569:161-166
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
Wu Z, Zhang Y, Liu Y, Chen X, Huang Z, Zhao X, He H, Deng Y
Life (Basel, Switzerland) 2021 Sep 10;11(9)
Life (Basel, Switzerland) 2021 Sep 10;11(9)
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Autophagy was activated against the damages of placentas caused by nano-copper oral exposure.
Kang M, Luo J, Zhao L, Shi F, Ye G, He X, Hao S, Yang D, Chen H, Guo H, Li Y, Tang H
Ecotoxicology and environmental safety 2021 Sep 1;220:112364
Ecotoxicology and environmental safety 2021 Sep 1;220:112364
Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p.
Zhang K, Wang Q, Zhao D, Liu Z
Biochemical genetics 2021 Sep 1;
Biochemical genetics 2021 Sep 1;
l-cysteine-modified chiral gold nanoparticles promote periodontal tissue regeneration.
Zhang S, Zhou H, Kong N, Wang Z, Fu H, Zhang Y, Xiao Y, Yang W, Yan F
Bioactive materials 2021 Oct;6(10):3288-3299
Bioactive materials 2021 Oct;6(10):3288-3299
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928
Toxicology 2021 Oct;462:152928
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
Deng YJ, Lin XP, Li XQ, Lu PF, Cai Y, Liu LL, Pei GC, Han M
Current medical science 2021 Oct;41(5):880-887
Current medical science 2021 Oct;41(5):880-887
Bergenin attenuates bleomycin-induced pulmonary fibrosis in mice via inhibiting TGF-β1 signaling pathway.
Li X, Wang Y, Liang J, Bi Z, Ruan H, Cui Y, Ma L, Wei Y, Zhou B, Zhang L, Zhou H, Yang C
Phytotherapy research : PTR 2021 Oct;35(10):5808-5822
Phytotherapy research : PTR 2021 Oct;35(10):5808-5822
USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy.
Liu T, Wang L, Liang P, Wang X, Liu Y, Cai J, She Y, Wang D, Wang Z, Guo Z, Bates S, Xia X, Huang J, Cui J
Cellular & molecular immunology 2021 Oct;18(10):2431-2442
Cellular & molecular immunology 2021 Oct;18(10):2431-2442
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery.
Tang Y, Liu J, Wang Y, Yang L, Han B, Zhang Y, Bai Y, Shen L, Li M, Jiang T, Ye Q, Yu X, Huang R, Zhang Z, Xu Y, Yao H
Autophagy 2021 Oct;17(10):2905-2922
Autophagy 2021 Oct;17(10):2905-2922
Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair.
Wang B, Cao C, Han D, Bai J, Guo J, Guo Q, Li D, Zhang J, Zhang Z, Wang Y, Tang J, Shen D, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112056
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112056
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Li X, Liu S, Chen X, Huang R, Ma L, Weng H, Yu Y, Zong X
NPJ breast cancer 2021 Oct 7;7(1):132
NPJ breast cancer 2021 Oct 7;7(1):132
Autophagy deficiency activates rDNA transcription.
Xu Y, Wu Y, Wang L, Ren Z, Song L, Zhang H, Qian C, Wang Q, He Z, Wan W
Autophagy 2021 Oct 6;:1-12
Autophagy 2021 Oct 6;:1-12
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J
International journal of molecular sciences 2021 Oct 24;22(21)
International journal of molecular sciences 2021 Oct 24;22(21)
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Yao H, Yan J, Shao P, Wang Y, Liu T, Jiang J, Liu T
Toxicology letters 2021 Oct 15;351:145-154
Toxicology letters 2021 Oct 15;351:145-154
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
Duan J, Chen H, Li Y, Xu D, Li X, Zhang Z, Cheng J, Yang L, Li Q
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
International journal of molecular sciences 2021 Oct 12;22(20)
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Kong L, Deng J, Zhou X, Cai B, Zhang B, Chen X, Chen Z, Wang W
Cell death & disease 2021 Oct 11;12(10):928
Cell death & disease 2021 Oct 11;12(10):928
Extracellular IL-37 promotes osteogenic and odontogenic differentiation of human dental pulp stem cells via autophagy.
Li N, Yan M, Chen Y, Wang Y, Wu J, Fu L, Yu J
Experimental cell research 2021 Oct 1;407(1):112780
Experimental cell research 2021 Oct 1;407(1):112780
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X, Wu C
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Overexpression of HIF-1α enhances the protective effect of mitophagy on steroid-induced osteocytes apoptosis.
Xu K, Lu C, Ren X, Wang J, Xu P, Zhang Y
Environmental toxicology 2021 Nov;36(11):2123-2137
Environmental toxicology 2021 Nov;36(11):2123-2137
eIF2A-knockout mice reveal decreased life span and metabolic syndrome.
Anderson R, Agarwal A, Ghosh A, Guan BJ, Casteel J, Dvorina N, Baldwin WM 3rd, Mazumder B, Nazarko TY, Merrick WC, Buchner DA, Hatzoglou M, Kondratov RV, Komar AA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21990
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21990
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Cell research 2021 Nov;31(11):1199-1211
Cell research 2021 Nov;31(11):1199-1211
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E2 Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
Chen Q, Li Z, Xu Z, Chen C, Wang J, Zhu J, Dong Z
Biological trace element research 2021 Nov;199(11):4119-4128
Biological trace element research 2021 Nov;199(11):4119-4128
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Yang X, Jin N, Wang Y, Yao Y, Wang Y, Li T, Liu C, Yu T, Yin H, Zhang Z, Cheng SY, Yue S
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C
Autophagy 2021 Nov;17(11):3592-3606
Autophagy 2021 Nov;17(11):3592-3606
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Zhang M, Yan W, Yu Y, Cheng J, Yi X, Guo T, Liu N, Shang J, Wang Z, Hu H, Chen L
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Xing Y, Wang L, Xu G, Guo S, Zhang M, Cheng G, Liu Y, Liu J
Research in veterinary science 2021 Nov;140:18-25
Research in veterinary science 2021 Nov;140:18-25
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
Li R, Yao G, Zhou L, Zhang M, Yan J, Wang X, Li Y
Microvascular research 2021 Nov;138:104230
Microvascular research 2021 Nov;138:104230
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Dong J, Zhang KJ, Li GC, Chen XR, Lin JJ, Li JW, Lv ZY, Deng ZZ, Dai J, Cao W, Jiang Q
Acta pharmacologica Sinica 2021 Nov 9;
Acta pharmacologica Sinica 2021 Nov 9;
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2021 Nov 6;:1-14
Autophagy 2021 Nov 6;:1-14
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
Wang T, Zhang L, Liang W, Liu S, Deng W, Liu Y, Liu Y, Song M, Guo K, Zhang Y
Autophagy 2021 Nov 5;:1-17
Autophagy 2021 Nov 5;:1-17
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
Guo X, Bao X, Wang X, Liu D, Liu P, Chi T, Ji X, Zheng Z, Chen G, Zou L
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Li D, Li Z, Zhang T, Peng B, Zhang Y, Sun H, Wang S
Toxins 2021 Nov 22;13(11)
Toxins 2021 Nov 22;13(11)
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Li M, Cheng W, Zhang L
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Su Q, Wu Q, Chen K, Wang J, Sarwar A, Zhang Y
Molecular biology reports 2021 Nov 18;
Molecular biology reports 2021 Nov 18;
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)
Microorganisms 2021 Nov 16;9(11)
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Xi H, Ren F, Li Y, Du Y, Wang L, Hu J
Biology of reproduction 2021 Nov 15;105(5):1344-1354
Biology of reproduction 2021 Nov 15;105(5):1344-1354
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Liu L, Wang J, Zhang J, Huang C, Yang Z, Cao Y
Cell biology and toxicology 2021 Nov 11;
Cell biology and toxicology 2021 Nov 11;
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)
Science advances 2021 May;7(22)
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Journal of applied toxicology : JAT 2021 May;41(5):745-754
17β-estradiol improves the developmental ability, inhibits reactive oxygen species levels and apoptosis of porcine oocytes by regulating autophagy events.
Duan J, Chen H, Xu D, Li Y, Li X, Cheng J, Hua R, Zhang Z, Yang L, Li Q
The Journal of steroid biochemistry and molecular biology 2021 May;209:105826
The Journal of steroid biochemistry and molecular biology 2021 May;209:105826
Acetylation of STX17 (syntaxin 17) controls autophagosome maturation.
Shen Q, Shi Y, Liu J, Su H, Huang J, Zhang Y, Peng C, Zhou T, Sun Q, Wan W, Liu W
Autophagy 2021 May;17(5):1157-1169
Autophagy 2021 May;17(5):1157-1169
Biosynthetic gold nanoparticles of Hibiscus syriacus L. callus potentiates anti-inflammation efficacy via an autophagy-dependent mechanism.
Xu XY, Tran THM, Perumalsamy H, Sanjeevram D, Kim YJ
Materials science & engineering. C, Materials for biological applications 2021 May;124:112035
Materials science & engineering. C, Materials for biological applications 2021 May;124:112035
Proteomic analysis of aged and OPTN E50K retina in the development of normal tension glaucoma.
Liu X, Wang Q, Shao Z, Zhang S, Hou M, Jiang M, Du M, Li J, Yuan H
Human molecular genetics 2021 May 31;30(11):1030-1044
Human molecular genetics 2021 May 31;30(11):1030-1044
Nuclear receptor coactivator 4-mediated ferritinophagy drives proliferation of dental pulp stem cells in hypoxia.
Yang A, Wang L, Jiang K, Lei L, Li H
Biochemical and biophysical research communications 2021 May 21;554:123-130
Biochemical and biophysical research communications 2021 May 21;554:123-130
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Wang JC, Huang Y, Zhang RX, Han ZJ, Zhou LL, Sun N, Dong WY, Zhuang GS
Biochemical and biophysical research communications 2021 May 21;554:1-6
Biochemical and biophysical research communications 2021 May 21;554:1-6
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Martin TG, Myers VD, Dubey P, Dubey S, Perez E, Moravec CS, Willis MS, Feldman AM, Kirk JA
Nature communications 2021 May 19;12(1):2942
Nature communications 2021 May 19;12(1):2942
Interfering with hyaluronic acid metabolism suppresses glioma cell proliferation by regulating autophagy.
Yan T, Chen X, Zhan H, Yao P, Wang N, Yang H, Zhang C, Wang K, Hu H, Li J, Sun J, Dong Y, Lu E, Zheng Z, Zhang R, Wang X, Ma J, Gao M, Ye J, Wang X, Teng L, Liu H, Zhao S
Cell death & disease 2021 May 13;12(5):486
Cell death & disease 2021 May 13;12(5):486
Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection.
Gestuveo RJ, Royle J, Donald CL, Lamont DJ, Hutchinson EC, Merits A, Kohl A, Varjak M
Nature communications 2021 May 13;12(1):2766
Nature communications 2021 May 13;12(1):2766
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, Xue H, Wu M, Xu L
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Lactobacillus salivarius ameliorated Mycoplasma gallisepticum-induced inflammatory injury and secondary Escherichia coli infection in chickens: Involvement of intestinal microbiota.
Wang J, Ishfaq M, Li J
Veterinary immunology and immunopathology 2021 Mar;233:110192
Veterinary immunology and immunopathology 2021 Mar;233:110192
Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway.
Hou J, Zhao L, Tang H, He X, Ye G, Shi F, Kang M, Chen H, Li Y
Biological trace element research 2021 Mar;199(3):1062-1073
Biological trace element research 2021 Mar;199(3):1062-1073
CXXC5 orchestrates Stat3/Erk/Akt signaling networks to modulate P. gingivalis-elicited autophagy in cementoblasts.
Ma L, Liu H, Wang X, Jiang C, Yao S, Guo Y, Wang H, Cao Z
Biochimica et biophysica acta. Molecular cell research 2021 Mar;1868(3):118923
Biochimica et biophysica acta. Molecular cell research 2021 Mar;1868(3):118923
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Feng X, Zhang H, Meng L, Song H, Zhou Q, Qu C, Zhao P, Li Q, Zou C, Liu X, Zhang Z
Autophagy 2021 Mar;17(3):723-742
Autophagy 2021 Mar;17(3):723-742
Hongjingtian injection protects against myocardial ischemia reperfusion-induced apoptosis by blocking ROS induced autophagic- flux.
Zhao J, Zhang J, Liu Q, Wang Y, Jin Y, Yang Y, Ni C, Zhang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111205
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111205
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b.
Li J, Yang T, Sha Z, Tang H, Hua X, Wang L, Wang Z, Gao Z, Sluijter JPG, Rowe GC, Das S, Yang L, Xiao J
Molecular therapy. Nucleic acids 2021 Mar 5;23:743-756
Molecular therapy. Nucleic acids 2021 Mar 5;23:743-756
Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory Actions.
Li J, Yang T, Tang H, Sha Z, Chen R, Chen L, Yu Y, Rowe GC, Das S, Xiao J
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Mar 3;29(3):1102-1119
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Mar 3;29(3):1102-1119
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
Li HG, Tian WH, Qin CL, Ye RR, Liu DH, Liu HW
Aging 2021 Mar 19;13(7):9704-9718
Aging 2021 Mar 19;13(7):9704-9718
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Zhang S, Shao Z, Liu X, Hou M, Cheng F, Lei D, Yuan H
Cell death discovery 2021 Mar 15;7(1):49
Cell death discovery 2021 Mar 15;7(1):49
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca2+/CaMKII signal pathway.
Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565
Aging 2021 Mar 10;13(7):9542-9565
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Li X, Sun L, Yan G, Yan X
Cellular signalling 2021 Jun;82:109956
Cellular signalling 2021 Jun;82:109956
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Guo W, Zhao Y, Li H, Lei L
Journal of periodontal research 2021 Jun;56(3):523-534
Journal of periodontal research 2021 Jun;56(3):523-534
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension.
Feng W, Wang J, Yan X, Zhang Q, Chai L, Wang Q, Shi W, Chen Y, Liu J, Qu Z, Li S, Xie X, Li M
Cell proliferation 2021 Jun;54(6):e13048
Cell proliferation 2021 Jun;54(6):e13048
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
Zhang X, Wei M, Fan J, Yan W, Zha X, Song H, Wan R, Yin Y, Wang W
Autophagy 2021 Jun;17(6):1519-1542
Autophagy 2021 Jun;17(6):1519-1542
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Ruan C, Wang C, Gong X, Zhang Y, Deng W, Zhou J, Huang D, Wang Z, Zhang Q, Guo A, Lu J, Gao J, Peng D, Xue Y
Autophagy 2021 Jun;17(6):1426-1447
Autophagy 2021 Jun;17(6):1426-1447
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster BM, Huang W, Kane M, Lederer WJ, Karbowski M
The Journal of cell biology 2021 Jun 7;220(6)
The Journal of cell biology 2021 Jun 7;220(6)
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2021 Jun 6;
Journal of applied toxicology : JAT 2021 Jun 6;
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis.
Zhang M, Zhang T, Song C, Qu J, Gu Y, Liu S, Li H, Xiao W, Kong L, Sun Y, Lv W
Journal of ethnopharmacology 2021 Jun 28;274:114064
Journal of ethnopharmacology 2021 Jun 28;274:114064
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Lu C, Wu B, Liao Z, Xue M, Zou Z, Feng J, Sheng J
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice.
Li H, Qin S, Liang Q, Xi Y, Bo W, Cai M, Tian Z
Biomedicines 2021 Jun 21;9(6)
Biomedicines 2021 Jun 21;9(6)
Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss.
Amegandjin CA, Choudhury M, Jadhav V, Carriço JN, Quintal A, Berryer M, Snapyan M, Chattopadhyaya B, Saghatelyan A, Di Cristo G
Nature communications 2021 Jun 16;12(1):3653
Nature communications 2021 Jun 16;12(1):3653
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.
Wu H, Feng K, Zhang C, Zhang H, Zhang J, Hua Y, Dong Z, Zhu Y, Yang S, Ma C
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Wang H, Yang C, Li Y, Zhao S, Ma P, Mao B
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Wang W, Qin Y, Song H, Wang L, Jia M, Zhao C, Gong M, Zhao W
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
Zhu F, Li X, Tang X, Jiang J, Han Y, Li Y, Ma C, Liu Z, He Y
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Autophagy inhibition and microRNA‑199a‑5p upregulation in paclitaxel‑resistant A549/T lung cancer cells.
Zeng T, Xu M, Zhang W, Gu X, Zhao F, Liu X, Zhang X
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
Zhang Q, Feng Z, Lu J, Lu J, Guan S, Chen Y
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Lu J, Liu M, Fan Y, Zheng H, Guan S
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.
Jia X, Zhang A, Li Z, Peng X, Tian X, Gao F
Journal of neurochemistry 2021 Jul;158(2):373-390
Journal of neurochemistry 2021 Jul;158(2):373-390
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Ferreira N, Gram H, Sorrentino ZA, Gregersen E, Schmidt SI, Reimer L, Betzer C, Perez-Gozalbo C, Beltoja M, Nagaraj M, Wang J, Nowak JS, Dong M, Willén K, Cholak E, Bjerregaard-Andersen K, Mendez N, Rabadia P, Shahnawaz M, Soto C, Otzen DE, Akbey Ü, Meyer M, Giasson BI, Romero-Ramos M, Jensen PH
Acta neuropathologica 2021 Jul;142(1):87-115
Acta neuropathologica 2021 Jul;142(1):87-115
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Zhang X, Lv S, Zhang W, Jia Q, Wang L, Ding Y, Yuan P, Zhu Y, Liu L, Li Y, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J
Biological trace element research 2021 Jul 30;
Biological trace element research 2021 Jul 30;
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Peng Y, Zhang Y, Zhang Y, Wang X, Xia Y
Chinese medicine 2021 Jul 28;16(1):66
Chinese medicine 2021 Jul 28;16(1):66
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Liu J, He J, Ge L, Xiao H, Huang Y, Zeng L, Jiang Z, Lu M, Hu Z
Stem cell research & therapy 2021 Jul 22;12(1):413
Stem cell research & therapy 2021 Jul 22;12(1):413
Activated autophagy restored the impaired frequency and function of regulatory T cells in chronic prostatitis.
Liu Y, Zhang Y, Zhang M, Meng J, Ma Q, Hao Z, Zheng M, Zhang L, Chen X, Liang C
The Prostate 2021 Jan;81(1):29-40
The Prostate 2021 Jan;81(1):29-40
The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury.
Wang Y, Zhu J, Liu Z, Shu S, Fu Y, Liu Y, Cai J, Tang C, Liu Y, Yin X, Dong Z
Redox biology 2021 Jan;38:101767
Redox biology 2021 Jan;38:101767
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
Wang J, Zhu H, Lin S, Wang K, Wang H, Liu Z
Journal of inorganic biochemistry 2021 Jan;214:111310
Journal of inorganic biochemistry 2021 Jan;214:111310
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Han F, Guo H, Wang L, Zhang Y, Sun L, Dai C, Wu X
Experimental eye research 2021 Jan;202:108366
Experimental eye research 2021 Jan;202:108366
Srag Regulates Autophagy via Integrating into a Preexisting Autophagy Pathway in Testis.
Cheng Y, Lai F, Wang X, Shang D, Zou J, Luo M, Xia X, Cheng H, Zhou R
Molecular biology and evolution 2021 Jan 4;38(1):128-141
Molecular biology and evolution 2021 Jan 4;38(1):128-141
Salidroside inhibits apoptosis and autophagy of cardiomyocyte by regulation of circular RNA hsa_circ_0000064 in cardiac ischemia-reperfusion injury.
Jin P, Li LH, Shi Y, Hu NB
Gene 2021 Jan 30;767:145075
Gene 2021 Jan 30;767:145075
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation.
Zhou Y, Yan M, Pan R, Wang Z, Tao X, Li C, Xia T, Liu X, Chang Q
Journal of ethnopharmacology 2021 Jan 30;265:113317
Journal of ethnopharmacology 2021 Jan 30;265:113317
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation.
Feng S, Qiu G, Yang L, Feng L, Fan X, Ren F, Huang K, Chen Y
Bioscience reports 2021 Jan 29;41(1)
Bioscience reports 2021 Jan 29;41(1)
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Zong DD, Liu XM, Li JH, Ouyang RY, Long YJ, Chen P, Chen Y
Respiratory research 2021 Jan 19;22(1):22
Respiratory research 2021 Jan 19;22(1):22
Atmospheric PM2.5 blocking up autophagic flux in HUVECs via inhibiting Sntaxin-17 and LAMP2.
Liu Y, Zhao D, Peng W, Xue P, Jiang X, Chen S, Gao H, Wang X, Feng S
Ecotoxicology and environmental safety 2021 Jan 15;208:111450
Ecotoxicology and environmental safety 2021 Jan 15;208:111450
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Xu C, Cao H, Sui Y, Zhang H, Shi C, Wu J, Ma R, Feng J
Cancer cell international 2021 Jan 12;21(1):48
Cancer cell international 2021 Jan 12;21(1):48
Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.
Qin S, Ye L, Zheng Y, Gao J
FEBS letters 2021 Feb;595(4):507-520
FEBS letters 2021 Feb;595(4):507-520
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome.
Rahim I, Sayed RK, Fernández-Ortiz M, Aranda-Martínez P, Guerra-Librero A, Fernández-Martínez J, Rusanova I, Escames G, Djerdjouri B, Acuña-Castroviejo D
Naunyn-Schmiedeberg's archives of pharmacology 2021 Feb;394(2):261-277
Naunyn-Schmiedeberg's archives of pharmacology 2021 Feb;394(2):261-277
Autophagy Induction Contributes to the Neuroprotective Impact of Intermittent Fasting on the Acutely Injured Spinal Cord.
Yuan W, He X, Morin D, Barrière G, Liu X, Li J, Zhu Y
Journal of neurotrauma 2021 Feb;38(3):373-384
Journal of neurotrauma 2021 Feb;38(3):373-384
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Shao L, Jiang GT, Yang XL, Zeng ML, Cheng JJ, Kong S, Dong X, Chen TX, Han S, Yin J, Liu WH, He XH, He C, Peng BW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
Liu Y, Wang Y, Liu J, Kang R, Tang D
Cancer gene therapy 2021 Feb;28(1-2):55-63
Cancer gene therapy 2021 Feb;28(1-2):55-63
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Yu Q, Cheng P, Wu J, Guo C
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells.
Zhao Y, Wang W, Pan W, Yu Y, Huang W, Gao J, Zhang Y, Zhang S
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Wang Y, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J
Biological trace element research 2021 Feb;199(2):703-711
Biological trace element research 2021 Feb;199(2):703-711
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy.
Wang R, Zhu Y, Ren C, Yang S, Tian S, Chen H, Jin M, Zhou H
Autophagy 2021 Feb;17(2):496-511
Autophagy 2021 Feb;17(2):496-511
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
Zhou K, Xu Y, Wang Q, Dong L
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
Deng Z, Sun M, Wu J, Fang H, Cai S, An S, Huang Q, Chen Z, Wu C, Zhou Z, Hu H, Zeng Z
Cell death & disease 2021 Feb 26;12(2):217
Cell death & disease 2021 Feb 26;12(2):217
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Zhang MH, Li J, Zhu XY, Zhang YQ, Ye ST, Leng YR, Yang T, Zhang H, Kong LY
Free radical biology & medicine 2021 Feb 20;164:1-12
Free radical biology & medicine 2021 Feb 20;164:1-12
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Regorafenib-Attenuated, Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway.
Li X, Ma L, Huang K, Wei Y, Long S, Liu Q, Zhang D, Wu S, Wang W, Yang G, Zhou H, Yang C
International journal of molecular sciences 2021 Feb 17;22(4)
International journal of molecular sciences 2021 Feb 17;22(4)
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Lv S, Yuan P, Lu C, Dong J, Li M, Qu F, Zhu Y, Zhang J
Aging 2021 Feb 11;13(4):5525-5538
Aging 2021 Feb 11;13(4):5525-5538
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway.
Lu Q, Gu W, Luo C, Wang L, Hua W, Sun Y, Tang L
Journal of ethnopharmacology 2021 Feb 10;266:113454
Journal of ethnopharmacology 2021 Feb 10;266:113454
ZFP91 is required for the maintenance of regulatory T cell homeostasis and function.
Wang A, Ding L, Wu Z, Ding R, Teng XL, Wang F, Hu Z, Chen L, Yu X, Zou Q
The Journal of experimental medicine 2021 Feb 1;218(2)
The Journal of experimental medicine 2021 Feb 1;218(2)
The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A.
Yu YG, Han JH, Xue HX, Li WZ, Wu WN, Yin YY
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1298-1307
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1298-1307
The abrupt pathological deterioration of cisplatin-induced acute kidney injury: Emerging of a critical time point.
Gong Q, Wang M, Jiang Y, Zha C, Yu D, Lei F, Luo Y, Feng Y, Yang S, Li J, Du L
Pharmacology research & perspectives 2021 Dec;9(6):e00895
Pharmacology research & perspectives 2021 Dec;9(6):e00895
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
Wang X, Wu F, Deng Y, Chai J, Zhang Y, He G, Li X
International journal of oncology 2021 Dec;59(6)
International journal of oncology 2021 Dec;59(6)
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Goose nephritic astrovirus infection increases autophagy, destroys intercellular junctions in renal tubular epithelial cells, and damages podocytes in the kidneys of infected goslings.
Huang H, Ding R, Chen Z, Yi Z, Wang H, Lv Y, Bao E
Veterinary microbiology 2021 Dec;263:109244
Veterinary microbiology 2021 Dec;263:109244
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
Meng Q, Zaharieva EK, Sasatani M, Kobayashi J
Redox report : communications in free radical research 2021 Dec;26(1):160-169
Redox report : communications in free radical research 2021 Dec;26(1):160-169
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle.
Lei Y, Xu X, Liu H, Chen L, Zhou H, Jiang J, Yang Y, Wu B
Autophagy 2021 Dec;17(12):4423-4441
Autophagy 2021 Dec;17(12):4423-4441
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Zhong S, Lian Y, Luo W, Luo R, Wu X, Ji J, Ji Y, Ding J, Wang X
Acta neuropathologica 2021 Dec;142(6):1003-1023
Acta neuropathologica 2021 Dec;142(6):1003-1023
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111
The international journal of biochemistry & cell biology 2021 Dec;141:106111
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
Wang B, Ji D, Xing W, Li F, Huang Z, Zheng W, Xue J, Zhu Y, Yang X
Cartilage 2021 Dec;13(2_suppl):592S-603S
Cartilage 2021 Dec;13(2_suppl):592S-603S
The unique Akt inhibitor SC66 suppressed AMPK activity and abolished autophagy through the EGFR-p62 pathway.
Hou B, Li E, Liang J, Liu S, Yang H, Liu L, Jiang X
Cell biology international 2021 Dec 2;
Cell biology international 2021 Dec 2;
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
Pulmonary Exposure to Copper Oxide Nanoparticles Leads to Neurotoxicity via Oxidative Damage and Mitochondrial Dysfunction.
Zhou H, Yao L, Jiang X, Sumayyah G, Tu B, Cheng S, Qin X, Zhang J, Zou Z, Chen C
Neurotoxicity research 2021 Aug;39(4):1160-1170
Neurotoxicity research 2021 Aug;39(4):1160-1170
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Wu W, Dong J, Gou H, Geng R, Yang X, Chen D, Xiang B, Zhang Z, Ren S, Chen L, Liu J
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Liu J, Liu L, Han YS, Yi J, Guo C, Zhao HQ, Ling J, Wang YH
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Tao M, Zheng D, Liang X, Wu D, Hu K, Jin J, He Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Yang C, Xu X, Dong X, Yang B, Dong W, Luo Y, Liu X, Wu Y, Wang J
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Zhang L, Zou L, Jiang X, Cheng S, Zhang J, Qin X, Qin Z, Chen C, Zou Z
Nanotoxicology 2021 Aug;15(6):779-797
Nanotoxicology 2021 Aug;15(6):779-797
Biosynthesis of gold nanoparticles using Nigella sativa and Curtobacterium proimmune K3 and evaluation of their anticancer activity.
Dhandapani S, Xu X, Wang R, Puja AM, Kim H, Perumalsamy H, Balusamy SR, Kim YJ
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112214
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112214
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Zhang Z, Mou Z, Xu C, Wu S, Dai X, Chen X, Ou Y, Chen Y, Yang C, Jiang H
Cell death & disease 2021 Aug 7;12(8):778
Cell death & disease 2021 Aug 7;12(8):778
Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy.
Wu C, Zhou XX, Li JZ, Qiang HF, Wang Y, Li G
Stem cell research & therapy 2021 Aug 5;12(1):437
Stem cell research & therapy 2021 Aug 5;12(1):437
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
Adenovirus Remodeling of the Host Proteome and Host Factors Associated with Viral Genomes.
Dybas JM, Lum KK, Kulej K, Reyes ED, Lauman R, Charman M, Purman CE, Steinbock RT, Grams N, Price AM, Mendoza L, Garcia BA, Weitzman MD
mSystems 2021 Aug 31;:e0046821
mSystems 2021 Aug 31;:e0046821
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Zhao Y, Lu J, Mao A, Zhang R, Guan S
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice.
Yan M, Wang Z, Xia T, Jin S, Liu Y, Hu H, Chang Q
Biomedicines 2021 Aug 2;9(8)
Biomedicines 2021 Aug 2;9(8)
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Jiang Y, Zhou Y, Xu W, Wang X, Jin H, Bao X, Lu C
Cell biology and toxicology 2021 Aug 17;
Cell biology and toxicology 2021 Aug 17;
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
Liu K, Qiu D, Liang X, Huang Y, Wang Y, Jia X, Li K, Zhao J, Du C, Qiu X, Cui J, Xiao Z, Qin Y, Zhang Q
Autophagy 2021 Aug 12;:1-17
Autophagy 2021 Aug 12;:1-17
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Liu X, Gu Y, Bian Y, Cai D, Li Y, Zhao Y, Zhang Z, Xue M, Zhang L
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Yang RZ, Xu WN, Zheng HL, Zheng XF, Li B, Jiang LS, Jiang SD
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
Nie L, Liu M, Chen J, Wu Q, Li Y, Yi J, Zheng X, Zhang J, Chu C, Yang J
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
Yang B, Zang J, Yuan W, Jiang X, Zhang F
Experimental and therapeutic medicine 2021 Apr;21(4):317
Experimental and therapeutic medicine 2021 Apr;21(4):317
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Kong XT, Wang Z, Mou JJ, Li CS, Xue HL, Wu M, Chen L, Xu JH, Xu LX
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
Liu S, Jiang X, Cui X, Wang J, Liu S, Li H, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Apr 9;12(4):385
Cell death & disease 2021 Apr 9;12(4):385
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
Lu J, Fan Y, Liu M, Zhang Q, Guan S
Toxicology 2021 Apr 30;454:152716
Toxicology 2021 Apr 30;454:152716
PINK1/Parkin-mediated mitophagy inhibits warangalone-induced mitochondrial apoptosis in breast cancer cells.
Mao L, Liu H, Zhang R, Deng Y, Hao Y, Liao W, Yuan M, Sun S
Aging 2021 Apr 30;13(9):12955-12972
Aging 2021 Apr 30;13(9):12955-12972
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Tan YZ, Xu XY, Dai JM, Yin Y, He XT, Zhang YL, Zhu TX, An Y, Tian BM, Chen FM
Stem cell research & therapy 2021 Apr 29;12(1):254
Stem cell research & therapy 2021 Apr 29;12(1):254
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Liu A, Wang W, Lu Z, Liu Z, Zhou W, Zhong Z, Ye Q
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Zhang W, Huang B, Gao L, Huang C
International journal of molecular sciences 2021 Apr 21;22(9)
International journal of molecular sciences 2021 Apr 21;22(9)
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Zhang M, Wu P, Li M, Guo Y, Tian T, Liao X, Tan S
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
Xiao W, Yeerken D, Li J, Li Z, Jiang L, Li D, Fu M, Ma L, Song Y, Zhang W, Zhan Q
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
LC3B/p62-mediated mitophagy protects A549 cells from resveratrol-induced apoptosis.
Zheng J, Wei S, Xiao T, Li G
Life sciences 2021 Apr 15;271:119139
Life sciences 2021 Apr 15;271:119139
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Hu J, Ding X, Tian S, Chu Y, Liu Z, Li Y, Li X, Wang G, Wang L, Wang Z
Cell death & disease 2021 Apr 12;12(4):391
Cell death & disease 2021 Apr 12;12(4):391
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W
Ecotoxicology and environmental safety 2021 Apr 10;216:112181
Ecotoxicology and environmental safety 2021 Apr 10;216:112181
Anti-glioblastoma Activity of Kaempferol via Programmed Cell Death Induction: Involvement of Autophagy and Pyroptosis.
Chen S, Ma J, Yang L, Teng M, Lai ZQ, Chen X, He J
Frontiers in bioengineering and biotechnology 2020;8:614419
Frontiers in bioengineering and biotechnology 2020;8:614419
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
Du J, Dong Z, Tan L, Tan M, Zhang F, Zhang K, Pan G, Li C, Shi S, Zhang Y, Liu Y, Cui H
Frontiers in cell and developmental biology 2020;8:607757
Frontiers in cell and developmental biology 2020;8:607757
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Zhan Y, Wang H, Zhang L, Pei F, Chen Z
Frontiers in cell and developmental biology 2020;8:605609
Frontiers in cell and developmental biology 2020;8:605609
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
Zhang W, Hou W, Chen M, Chen E, Xue D, Ye C, Li W, Pan Z
Frontiers in cell and developmental biology 2020;8:576104
Frontiers in cell and developmental biology 2020;8:576104
NDUFA4L2 Regulated by HIF-1α Promotes Metastasis and Epithelial-Mesenchymal Transition of Osteosarcoma Cells Through Inhibiting ROS Production.
Xu WN, Yang RZ, Zheng HL, Jiang LS, Jiang SD
Frontiers in cell and developmental biology 2020;8:515051
Frontiers in cell and developmental biology 2020;8:515051
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Zhang Z, Han K, Wang C, Sun C, Jia N
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Yen IC, Lin JC, Chen Y, Tu QW, Lee SY
The American journal of Chinese medicine 2020;48(8):1859-1874
The American journal of Chinese medicine 2020;48(8):1859-1874
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
Xu YL, Liu XY, Cheng SB, He PK, Hong MK, Chen YY, Zhou FH, Jia YH
The American journal of Chinese medicine 2020;48(8):1821-1840
The American journal of Chinese medicine 2020;48(8):1821-1840
4-Acetylantrocamol LT3, a New Ubiquinone from Antrodia cinnamomea, Inhibits Hepatocellular Carcinoma HepG2 Cell Growth by Targeting YAP/TAZ, mTOR, and WNT/β-Catenin Signaling.
Chen YL, Yen IC, Lin KT, Lai FY, Lee SY
The American journal of Chinese medicine 2020;48(5):1243-1261
The American journal of Chinese medicine 2020;48(5):1243-1261
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
Huang Y, Liao Y, Zhang H, Li S
The Journal of toxicological sciences 2020;45(9):559-567
The Journal of toxicological sciences 2020;45(9):559-567
Yi-Zhi-Fang-Dai Formula Exerts a Protective Effect on the Injury of Tight Junction Scaffold Proteins in Vitro and in Vivo by Mediating Autophagy through Regulation of the RAGE/CaMKKβ/AMPK/mTOR Pathway.
Chan Y, Chen W, Chen Y, Lv Z, Wan W, Li Y, Zhang C
Biological & pharmaceutical bulletin 2020;43(12):1847-1858
Biological & pharmaceutical bulletin 2020;43(12):1847-1858
Protective Role of Coenzyme Q10 in Acute Sepsis-Induced Liver Injury in BALB/c Mice.
Li QW, Yang Q, Liu HY, Wu YL, Hao YH, Zhang XQ
BioMed research international 2020;2020:7598375
BioMed research international 2020;2020:7598375
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
Feng TY, Li Q, Ren F, Xi HM, Lv DL, Li Y, Hu JH
Oxidative medicine and cellular longevity 2020;2020:5954635
Oxidative medicine and cellular longevity 2020;2020:5954635
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.
Cheng Y, Pan X, Wang J, Li X, Yang S, Yin R, Ma A, Zhu X
Oxidative medicine and cellular longevity 2020;2020:3186306
Oxidative medicine and cellular longevity 2020;2020:3186306
Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway.
Zhao X, Liu L, Jiang Y, Silva M, Zhen X, Zheng W
Oxidative medicine and cellular longevity 2020;2020:2524174
Oxidative medicine and cellular longevity 2020;2020:2524174
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Shi C, Lan W, Wang Z, Yang D, Wei J, Liu Z, Teng Y, Gu M, Yuan T, Cao F, Zhou J, Li Y
Cancer cell international 2020;20:442
Cancer cell international 2020;20:442
Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy.
Williams T, Sorrentino Z, Weinrich M, Giasson BI, Chakrabarty P
Brain communications 2020;2(2):fcaa090
Brain communications 2020;2(2):fcaa090
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice.
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, Xu R
International journal of biological sciences 2020;16(2):284-297
International journal of biological sciences 2020;16(2):284-297
RAB37 multiple alleles, transcription activation and evolution in mammals.
Xu X, Hu M, Ying R, Zou J, Lin L, Cheng H, Zhou R
International journal of biological sciences 2020;16(15):2964-2973
International journal of biological sciences 2020;16(15):2964-2973
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Xu JH, Wang Z, Mou JJ, Zhao XY, Geng XC, Wu M, Xue HL, Chen L, Xu LX
PloS one 2020;15(11):e0241561
PloS one 2020;15(11):e0241561
Gallbladder Cancer Progression Is Reversed by Nanomaterial-Induced Photothermal Therapy in Combination with Chemotherapy and Autophagy Inhibition.
Cai Q, Wang X, Wang S, Jin L, Ding J, Zhou D, Ma F
International journal of nanomedicine 2020;15:253-262
International journal of nanomedicine 2020;15:253-262
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hongna Y, Hongzhao T, Quan L, Delin F, Guijun L, Xiaolin L, Fulin G, Zhongren S
Frontiers in neuroscience 2020;14:616864
Frontiers in neuroscience 2020;14:616864
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
Zhang Y, Huang N, Xu J, Zheng W, Cui X
Drug design, development and therapy 2020;14:4749-4763
Drug design, development and therapy 2020;14:4749-4763
Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis.
You G, Long X, Song F, Huang J, Tian M, Xiao Y, Deng S, Wu Q
Drug design, development and therapy 2020;14:457-468
Drug design, development and therapy 2020;14:457-468
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Li Z, Cheng J, Liu J
Drug design, development and therapy 2020;14:2645-2655
Drug design, development and therapy 2020;14:2645-2655
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
Wang MM, Zhang M, Feng YS, Xing Y, Tan ZX, Li WB, Dong F, Zhang F
Frontiers in cellular neuroscience 2020;14:134
Frontiers in cellular neuroscience 2020;14:134
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
Xiang S, Chen K, Xu L, Wang T, Guo C
Drug design, development and therapy 2020;14:129-143
Drug design, development and therapy 2020;14:129-143
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Xu X, Chen B, Huang Q, Wu Y, Liang T
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation.
Zhang T, Wang H, Lu M, Zhao K, Yin J, Liu Y, Sun Y
American journal of translational research 2020;12(9):5332-5342
American journal of translational research 2020;12(9):5332-5342
Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells.
Zuo H, Chen C, Ma L, Min QX, Shen YH
American journal of translational research 2020;12(10):6478-6489
American journal of translational research 2020;12(10):6478-6489
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
Li W, Qin X, Wang B, Xu G, Zhang J, Jiang X, Chen C, Qiu F, Zou Z
Cancer management and research 2020;12:6563-6573
Cancer management and research 2020;12:6563-6573
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Wang C, Shi Z, Hong Z, Pan J, Chen Z, Qiu C, Zhuang H, Zheng X
Cancer management and research 2020;12:12185-12195
Cancer management and research 2020;12:12185-12195
Poly C Binding Protein 1 Regulates p62/SQSTM1 mRNA Stability and Autophagic Degradation to Repress Tumor Progression.
Zhang W, Zhang S, Guan W, Huang Z, Kong J, Huang C, Wang H, Yang S
Frontiers in genetics 2020;11:930
Frontiers in genetics 2020;11:930
Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy.
Wen X, Liu L, Li S, Lin P, Chen H, Zhou D, Tang K, Wang A, Jin Y
Frontiers in physiology 2020;11:868
Frontiers in physiology 2020;11:868
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
Sun X, Wang D, Zhang T, Lu X, Duan F, Ju L, Zhuang X, Jiang X
Frontiers in pharmacology 2020;11:84
Frontiers in pharmacology 2020;11:84
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Zheng Y, Zhu G, Tang Y, Yan J, Han S, Yin J, Peng B, He X, Liu W
Frontiers in microbiology 2020;11:78
Frontiers in microbiology 2020;11:78
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Wang N, Muhetaer G, Zhang X, Yang B, Wang C, Zhang Y, Wang X, Zhang J, Wang S, Zheng Y, Zhang F, Wang Z
Frontiers in pharmacology 2020;11:591400
Frontiers in pharmacology 2020;11:591400
Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux.
He X, Yuan W, Liu F, Feng J, Guo Y
Frontiers in pharmacology 2020;11:586302
Frontiers in pharmacology 2020;11:586302
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Ding W, Ding Z, Wang Y, Zhu Y, Gao Q, Cao W, Du R
Frontiers in pharmacology 2020;11:573870
Frontiers in pharmacology 2020;11:573870
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Wang Z, Xu JH, Mou JJ, Kong XT, Wu M, Xue HL, Xu LX
Frontiers in physiology 2020;11:408
Frontiers in physiology 2020;11:408
The Effect of Autophagy on Chronic Intermittent Hypobaric Hypoxia Ameliorating Liver Damage in Metabolic Syndrome Rats.
Cui F, Hu HF, Guo J, Sun J, Shi M
Frontiers in physiology 2020;11:13
Frontiers in physiology 2020;11:13
NLRC5 Inhibits Inflammation of Secretory Phase Ectopic Endometrial Stromal Cells by Up-Regulating Autophagy in Ovarian Endometriosis.
He R, Liu X, Zhang J, Wang Z, Wang W, Fu L, Fan Y, Sun S, Cao Y, Zhan L, Shui L
Frontiers in pharmacology 2020;11:1281
Frontiers in pharmacology 2020;11:1281
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Zhou B, Yang C, Yan X, Shi Z, Xiao H, Wei X, Jiang N, Wu Z
Frontiers in oncology 2020;10:606790
Frontiers in oncology 2020;10:606790
siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.
Li P, Cao G, Huang Y, Wu W, Chen B, Wang Z, Xiong M
Frontiers in oncology 2020;10:541262
Frontiers in oncology 2020;10:541262
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
Wu C, Yang M, Liu R, Hu H, Ji L, Zhang X, Huang S, Wang L
Frontiers in cellular and infection microbiology 2020;10:484
Frontiers in cellular and infection microbiology 2020;10:484
PIWI-Interacting RNA-004800 Is Regulated by S1P Receptor Signaling Pathway to Keep Myeloma Cell Survival.
Ma H, Wang H, Tian F, Zhong Y, Liu Z, Liao A
Frontiers in oncology 2020;10:438
Frontiers in oncology 2020;10:438
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Xu LY, Mu M, Wang ML, Liu JC, Zhou YJ, Wu J, Jiang BY, Chen MG, Hu D, Tao XR
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
FTO accelerates ovarian cancer cell growth by promoting proliferation, inhibiting apoptosis, and activating autophagy.
Zhao L, Kong X, Zhong W, Wang Y, Li P
Pathology, research and practice 2020 Sep;216(9):153042
Pathology, research and practice 2020 Sep;216(9):153042
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
Yang F, Qu Q, Zhao C, Liu X, Yang P, Li Z, Han L, Shi X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Zhao Y, Tang J, Yang D, Tang C, Chen J
Journal of dairy science 2020 Sep;103(9):8350-8359
Journal of dairy science 2020 Sep;103(9):8350-8359
The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo.
Bressan C, Pecora A, Gagnon D, Snapyan M, Labrecque S, De Koninck P, Parent M, Saghatelyan A
eLife 2020 Sep 28;9
eLife 2020 Sep 28;9
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
Wu CH, Ou CH, Yen IC, Lee SY
International journal of molecular sciences 2020 Sep 22;21(18)
International journal of molecular sciences 2020 Sep 22;21(18)
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy.
Ye X, Xie G, Liu Z, Tang J, Cui M, Wang C, Guo C, Tang J
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 18;26:e922703
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 18;26:e922703
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Liu Z, Lv X, Xu L, Liu X, Zhu X, Song E, Song Y
Particle and fibre toxicology 2020 Sep 18;17(1):46
Particle and fibre toxicology 2020 Sep 18;17(1):46
Cellular evidence of autophagy in Sertoli cells during spermatogenesis in goats.
Qu W, Tarique I, Deng B, Zhang Y, Haseeb A, Chen Q, Yang P
Theriogenology 2020 Sep 15;154:237-245
Theriogenology 2020 Sep 15;154:237-245
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Yuan M, Yang X, Duscher D, Xiong H, Ren S, Xu X, Wang C, Chen J, Liu Y, Machens HG, Chen Z
Life sciences 2020 Sep 1;256:118022
Life sciences 2020 Sep 1;256:118022
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Fu N, Du H, Li D, Lu Y, Li W, Wang Y, Kong L, Du J, Zhao S, Ren W, Han F, Wang R, Zhang Y, Nan Y
Life sciences 2020 Sep 1;256:117911
Life sciences 2020 Sep 1;256:117911
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
Chen Y, Xie X, Wang C, Hu Y, Zhang H, Zhang L, Tu S, He Y, Li Y
Cell death & disease 2020 Sep 1;11(8):712
Cell death & disease 2020 Sep 1;11(8):712
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Wang L, Xu X, Liu T, Wang J, Shen J, Guo M, Wu Y, Zhai X, Zuo D
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Lv S, Yuan P, Dong J, Lu C, Li M, Qu F, Zhu Y, Yuan Z, Zhang J
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Activated FMS-like tyrosine kinase 3 ameliorates angiotensin II-induced cardiac remodelling.
Ma W, Liang F, Zhan H, Jiang X, Gao C, Zhang X, Zhang K, Sun Q, Hu H, Zhao Z
Acta physiologica (Oxford, England) 2020 Oct;230(2):e13519
Acta physiologica (Oxford, England) 2020 Oct;230(2):e13519
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma.
Yu X, Fan H, Jiang X, Zheng W, Yang Y, Jin M, Ma X, Jiang W
Oncology letters 2020 Oct;20(4):52
Oncology letters 2020 Oct;20(4):52
Phosphorylation of PRAS40 contributes to the activation of the PI3K/AKT/mTOR signaling pathway and the inhibition of autophagy following status epilepticus in rats.
Lin J, Fang Y, Zhang M, Wang X, Li L, He M, Xue A, Zhu K, Shen Y, Li B
Experimental and therapeutic medicine 2020 Oct;20(4):3625-3632
Experimental and therapeutic medicine 2020 Oct;20(4):3625-3632
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
Lu J, Lu J, Chen Y, Feng Z, Liu S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein.
Torkzaban B, Natarajaseenivasan K, Mohseni Ahooyi T, Shekarabi M, Amini S, Langford TD, Khalili K
Cell death & disease 2020 Oct 8;11(10):835
Cell death & disease 2020 Oct 8;11(10):835
Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation.
Zhai C, Feng W, Shi W, Wang J, Zhang Q, Yan X, Wang Q, Li S, Liu L, Pan Y, Zhu Y, Chai L, Li C, Liu P, Chen Y, Li M
European journal of pharmacology 2020 Oct 5;884:173302
European journal of pharmacology 2020 Oct 5;884:173302
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Shi X, Zhang T, Lou H, Song H, Li C, Fan P
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Lu J, Meng Z, Chen Y, Yu L, Gao B, Zheng Y, Guan S
Food & function 2020 Oct 21;11(10):9208-9215
Food & function 2020 Oct 21;11(10):9208-9215
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Li Y, Wu J, Yu S, Zhu J, Zhou Y, Wang P, Li L, Zhao Y
Brain research 2020 Oct 15;1745:146948
Brain research 2020 Oct 15;1745:146948
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
Sun Y, He L, Wang T, Hua W, Qin H, Wang J, Wang L, Gu W, Li T, Li N, Liu X, Chen F, Tang L
Molecular neurobiology 2020 Nov;57(11):4628-4641
Molecular neurobiology 2020 Nov;57(11):4628-4641
Past Exposure to Cigarette Smoke Aggravates Cognitive Impairment in a Rat Model of Vascular Dementia via Neuroinflammation.
Meng N, Dong Y, Huo T, Song M, Jiang X, Xiao Y, Lv P
Cellular and molecular neurobiology 2020 Nov 6;
Cellular and molecular neurobiology 2020 Nov 6;
CdSe/ZnS quantum dots induced spermatogenesis dysfunction via autophagy activation.
Yang Q, Li F, Miao Y, Luo X, Dai S, Liu J, Niu W, Sun Y
Journal of hazardous materials 2020 Nov 5;398:122327
Journal of hazardous materials 2020 Nov 5;398:122327
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Ding S, Ma N, Liu H, Tang M, Mei J
Aging 2020 Nov 24;12(24):25505-25527
Aging 2020 Nov 24;12(24):25505-25527
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991
Cell death & disease 2020 Nov 17;11(11):991
Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative.
Üner G, Tag Ö, Erzurumlu Y, Kirmizibayrak PB, Bedir E
Chemical research in toxicology 2020 Nov 16;33(11):2880-2891
Chemical research in toxicology 2020 Nov 16;33(11):2880-2891
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells.
Shao CS, Zhou XH, Zheng XX, Huang Q
Journal of ethnopharmacology 2020 Nov 15;262:113213
Journal of ethnopharmacology 2020 Nov 15;262:113213
Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.
Cen X, Chen Y, Xu X, Wu R, He F, Zhao Q, Sun Q, Yi C, Wu J, Najafov A, Xia H
Nature communications 2020 Nov 12;11(1):5731
Nature communications 2020 Nov 12;11(1):5731
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Sun X, Liu H, Sun Z, Zhang B, Wang X, Liu T, Pan T, Gao Y, Jiang X, Li H
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Wang J, Liu X, Zheng H, Liu Q, Zhang H, Wang X, Shen T, Wang S, Ren D
Chemico-biological interactions 2020 Nov 1;331:109279
Chemico-biological interactions 2020 Nov 1;331:109279
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
Xu Y, Wang X, Geng N, Zhu Y, Zhang S, Liu Y, Liu J
Ecotoxicology and environmental safety 2020 May;194:110414
Ecotoxicology and environmental safety 2020 May;194:110414
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
Zeng Y, Guo Z, Hu Z, Liu M, Chen Y, Chen S, Peng B, Zhang P, Wu Z, Luo H, Zhong F, Jiang K, Lu Y, Yuan G, He S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD
Nature communications 2020 May 8;11(1):2306
Nature communications 2020 May 8;11(1):2306
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
Tian Y, Guo H, Miao X, Xu J, Yang R, Zhao L, Liu J, Yang L, Gao F, Zhang W, Liu Q, Sun S, Tian Y, Li H, Huang J, Gu C, Liu S, Feng X
Cell death & disease 2020 May 5;11(5):319
Cell death & disease 2020 May 5;11(5):319
The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway.
Shao Q, Liu T, Wang W, Duan Q, Liu T, Xu L, Huang G, Chen Z
Journal of ethnopharmacology 2020 May 23;254:112611
Journal of ethnopharmacology 2020 May 23;254:112611
NPRL2 promotes docetaxel chemoresistance in castration resistant prostate cancer cells by regulating autophagy through the mTOR pathway.
Luo S, Shao L, Chen Z, Hu D, Jiang L, Tang W
Experimental cell research 2020 May 15;390(2):111981
Experimental cell research 2020 May 15;390(2):111981
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Chen T, Zhang W, Huang B, Chen X, Huang C
Cells 2020 May 13;9(5)
Cells 2020 May 13;9(5)
Impairment of Proteasome and Autophagy Underlying the Pathogenesis of Leukodystrophy.
Lin DS, Ho CS, Huang YW, Wu TY, Lee TH, Huang ZD, Wang TJ, Yang SJ, Chiang MF
Cells 2020 May 1;9(5)
Cells 2020 May 1;9(5)
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Yan K, Wu C, Ye Y, Li L, Wang X, He W, Ren S, Xu Y
Cell proliferation 2020 Mar;53(3):e12778
Cell proliferation 2020 Mar;53(3):e12778
Autophagy in endothelial cells regulates their haematopoiesis-supporting ability.
Lyu ZS, Cao XN, Wen Q, Mo XD, Zhao HY, Chen YH, Wang Y, Chang YJ, Xu LP, Zhang XH, Kong Y, Huang XJ
EBioMedicine 2020 Mar;53:102677
EBioMedicine 2020 Mar;53:102677
Autophagic-CTSB-inflammasome axis modulates hepatic stellate cells activation in arsenic-induced liver fibrosis.
Tao Y, Qiu T, Yao X, Jiang L, Wang N, Jia X, Wei S, Wang Z, Pei P, Zhang J, Zhu Y, Yang G, Liu X, Liu S, Sun X
Chemosphere 2020 Mar;242:124959
Chemosphere 2020 Mar;242:124959
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Ma R, Zhang BW, Zhang ZB, Deng QJ
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, Xu Z, Wang X, Wang Y, Zhu Y, Wang W
Archives of oral biology 2020 Mar;111:104646
Archives of oral biology 2020 Mar;111:104646
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
Irungbam K, Churin Y, Matono T, Weglage J, Ocker M, Glebe D, Hardt M, Koeppel A, Roderfeld M, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
Zhu B, Jiang Q, Que G, Dai Z, Wu Y
Journal of oral science 2020 Mar 28;62(2):184-188
Journal of oral science 2020 Mar 28;62(2):184-188
High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells.
Li K, Deng Y, Deng G, Chen P, Wang Y, Wu H, Ji Z, Yao Z, Zhang X, Yu B, Zhang K
Stem cell research & therapy 2020 Mar 20;11(1):131
Stem cell research & therapy 2020 Mar 20;11(1):131
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Choi I, Zhang Y, Seegobin SP, Pruvost M, Wang Q, Purtell K, Zhang B, Yue Z
Nature communications 2020 Mar 13;11(1):1386
Nature communications 2020 Mar 13;11(1):1386
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Yu M, Zeng M, Pan Z, Wu F, Guo L, He G
European journal of medicinal chemistry 2020 Mar 1;189:112076
European journal of medicinal chemistry 2020 Mar 1;189:112076
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Feng J, Zhang Y, Ren X, Li D, Fu H, Liu C, Zhou W, Liu Q, Liu Q, Wu M
Oncogene 2020 Jun;39(23):4551-4566
Oncogene 2020 Jun;39(23):4551-4566
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Zhou H, Xu C, Lee H, Yoon Y, Chen W
Molecular metabolism 2020 Jun;36:100971
Molecular metabolism 2020 Jun;36:100971
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
Wang Y, Hao J, Zhang S, Li L, Wang R, Zhu Y, Liu Y, Liu J
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Mooli RGR, Mukhi D, Watt M, Edmunds L, Xie B, Capooci J, Reslink M, Eze C, Mills A, Stolz DB, Jurczak M, Ramakrishnan SK
Metabolism: clinical and experimental 2020 Jun;107:154225
Metabolism: clinical and experimental 2020 Jun;107:154225
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
Liang C, Feng Z, Manthari RK, Wang C, Han Y, Fu W, Wang J, Zhang J
Journal of hazardous materials 2020 Jun 5;391:122227
Journal of hazardous materials 2020 Jun 5;391:122227
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159
Aging 2020 Jun 24;12(12):12142-12159
The in vitro effects of phospholipase D1-mTOR axis in liver fibrogenesis.
Chang Y, Xia L, Song M, Tang M, Patpur BK, Li J, Yang W, Yang C
Life sciences 2020 Jun 15;251:117595
Life sciences 2020 Jun 15;251:117595
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Liu X, Mi X, Wang Z, Zhang M, Hou J, Jiang S, Wang Y, Chen C, Li W
Cell death & disease 2020 Jun 12;11(6):454
Cell death & disease 2020 Jun 12;11(6):454
Siderophores induce mitophagy-dependent apoptosis in platelets.
Wang W, Lu Y, Wang Y, Zhang Y, Xia B, Cao J
Annals of translational medicine 2020 Jul;8(14):879
Annals of translational medicine 2020 Jul;8(14):879
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Wang J, Zhu H, Wang K, Yang Z, Liu Z
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS.
Liu H, You L, Wu J, Zhao M, Guo R, Zhang H, Su R, Mao Q, Deng D, Hao Y
Journal of leukocyte biology 2020 Jul;108(1):253-266
Journal of leukocyte biology 2020 Jul;108(1):253-266
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
Pang C, Song C, Li Y, Wang Q, Zhu X, Wu J, Tian Y, Fan H, Hu J, Li C, Wang B, Li X, Liu W, Fan L
Nanoscale research letters 2020 Jul 8;15(1):143
Nanoscale research letters 2020 Jul 8;15(1):143
Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway.
Mei ZG, Huang YG, Feng ZT, Luo YN, Yang SB, Du LP, Jiang K, Liu XL, Fu XY, Deng YH, Zhou HJ
Aging 2020 Jul 3;12(13):13187-13205
Aging 2020 Jul 3;12(13):13187-13205
Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss.
Zhang L, Qi M, Chen J, Zhao J, Li L, Hu J, Jin Y, Liu W
Stem cell research & therapy 2020 Jul 3;11(1):269
Stem cell research & therapy 2020 Jul 3;11(1):269
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy.
Sorrentino ZA, Hass E, Vijayaraghavan N, Gorion KM, Riffe CJ, Dhillon JS, Giasson BI
Neuroscience letters 2020 Jul 27;732:135017
Neuroscience letters 2020 Jul 27;732:135017
Dehydroandrographolide inhibits mastitis by activating autophagy without affecting intestinal flora.
Guo W, Liu J, Zhang Y, Ma H, Li Y, Gong Q, Cao Y, Hu G, Xie S, Fu S
Aging 2020 Jul 23;12(14):14050-14065
Aging 2020 Jul 23;12(14):14050-14065
Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses.
Liu L, Chen S, Yu M, Ge C, Ren M, Liu B, Yang X, Christian TW Jr, Hou YM, Zou J, Zhu WG, Luo J
Cell death & disease 2020 Jul 23;11(7):563
Cell death & disease 2020 Jul 23;11(7):563
PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.
Zheng X, Wei J, Li W, Li X, Wang W, Guo J, Fu Z
Aging 2020 Jul 20;12(16):16390-16409
Aging 2020 Jul 20;12(16):16390-16409
N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells.
Chen YC, Navarrete MS, Wang Y, McClintock NC, Sakurai R, Wang F, Chen KT, Chou TF, Rehan VK, Lee DJ, Diaz B
Scientific reports 2020 Jul 20;10(1):11952
Scientific reports 2020 Jul 20;10(1):11952
Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.
Xiang Q, Wan P, Yang G, Huang S, Qin M, Yang H, Luo Z, Wu K, Wu J
Viruses 2020 Jul 14;12(7)
Viruses 2020 Jul 14;12(7)
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Zhao X, Shi Y, Zhang D, Tong X, Sun Y, Xue X, Fu J
Life sciences 2020 Jul 1;252:117662
Life sciences 2020 Jul 1;252:117662
Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy.
Xu D, Liu J, Ma H, Guo W, Wang J, Kan X, Li Y, Gong Q, Cao Y, Cheng J, Fu S
International immunopharmacology 2020 Jan;78:105983
International immunopharmacology 2020 Jan;78:105983
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
Wang Y, Huang Y, Liu J, Zhang J, Xu M, You Z, Peng C, Gong Z, Liu W
EMBO reports 2020 Jan 7;21(1):e48335
EMBO reports 2020 Jan 7;21(1):e48335
A robust TDP-43 knock-in mouse model of ALS.
Huang SL, Wu LS, Lee M, Chang CW, Cheng WC, Fang YS, Chen YR, Cheng PL, Shen CJ
Acta neuropathologica communications 2020 Jan 21;8(1):3
Acta neuropathologica communications 2020 Jan 21;8(1):3
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Liu Y, Fan D
Nutrients 2020 Jan 18;12(1)
Nutrients 2020 Jan 18;12(1)
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Wu Q, Zhang M, Liu X, Zhang J, Wang H
International journal of molecular medicine 2020 Feb;45(2):475-484
International journal of molecular medicine 2020 Feb;45(2):475-484
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina.
Li Z, Li H, Xu X, Wang L, Liu B, Zheng W, Lian L, Song Y, Xia X, Hou L, Cheng H, Zhou R
Cell death and differentiation 2020 Feb;27(2):556-572
Cell death and differentiation 2020 Feb;27(2):556-572
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures.
Hu LD, Wang J, Chen XJ, Yan YB
Biochimica et biophysica acta. Molecular cell research 2020 Feb;1867(2):118617
Biochimica et biophysica acta. Molecular cell research 2020 Feb;1867(2):118617
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
Ying C, Ying L, Yanxia L, Le W, Lili C
Acta histochemica 2020 Feb;122(2):151485
Acta histochemica 2020 Feb;122(2):151485
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Lou L, Tian M, Chang J, Li F, Zhang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy.
Li G, Song Y, Liao Z, Wang K, Luo R, Lu S, Zhao K, Feng X, Liang H, Ma L, Wang B, Ke W, Yin H, Zhan S, Li S, Wu X, Zhang Y, Yang C
Cell death & disease 2020 Feb 6;11(2):103
Cell death & disease 2020 Feb 6;11(2):103
Nobiletin Triggers Reactive Oxygen Species-Mediated Pyroptosis through Regulating Autophagy in Ovarian Cancer Cells.
Zhang R, Chen J, Mao L, Guo Y, Hao Y, Deng Y, Han X, Li Q, Liao W, Yuan M
Journal of agricultural and food chemistry 2020 Feb 5;68(5):1326-1336
Journal of agricultural and food chemistry 2020 Feb 5;68(5):1326-1336
Heterogeneous Responses of Gastric Cancer Cell Lines to Tenovin-6 and Synergistic Effect with Chloroquine.
Ke X, Qin Q, Deng T, Liao Y, Gao SJ
Cancers 2020 Feb 5;12(2)
Cancers 2020 Feb 5;12(2)
Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34.
Xie W, Jin S, Wu Y, Xian H, Tian S, Liu DA, Guo Z, Cui J
Cell reports 2020 Feb 25;30(8):2807-2819.e4
Cell reports 2020 Feb 25;30(8):2807-2819.e4
Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.
Wang Y, Ji L, Peng Z, Lai R, Zhang X, Xu Y, Chen Z, Liu R, Zhong Y, Hu H, Wang L
Molecular and cellular endocrinology 2020 Feb 15;502:110674
Molecular and cellular endocrinology 2020 Feb 15;502:110674
Treadmill exercise improves neurological function by inhibiting autophagy and the binding of HMGB1 to Beclin1 in MCAO juvenile rats.
Pan G, Jin L, Shen W, Zhang J, Pan J, Cheng J, Xie Q, Hu Q, Wu S, Zhang H, Chen X
Life sciences 2020 Feb 15;243:117279
Life sciences 2020 Feb 15;243:117279
MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.
Liu J, Zhu Z, Liu Y, Wei L, Li B, Mao F, Zhang J, Wang Y, Liu Y
Life sciences 2020 Feb 1;242:117228
Life sciences 2020 Feb 1;242:117228
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Zhu L, Duan W, Wu G, Zhang D, Wang L, Chen D, Chen Z, Yang B
Annals of translational medicine 2020 Dec;8(23):1586
Annals of translational medicine 2020 Dec;8(23):1586
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
E L, Jiang H
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Tian J, Yang L, Wang P, Yang L, Fan Z
Neurochemical research 2020 Dec;45(12):2926-2938
Neurochemical research 2020 Dec;45(12):2926-2938
Disruption of the Keap1/Nrf2-Antioxidant Response System After Chronic Doxorubicin Exposure In Vivo.
Nordgren KKS, Wallace KB
Cardiovascular toxicology 2020 Dec;20(6):557-570
Cardiovascular toxicology 2020 Dec;20(6):557-570
Identification of curcumin as a novel natural inhibitor of rDNA transcription.
Xu Y, Wu Y, Wang L, Qian C, Wang Q, Wan W
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3362-3374
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3362-3374
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Xu J, Wang Z, Huang Y, Wang Y, Xiang L, He X
Steroids 2020 Dec;164:108737
Steroids 2020 Dec;164:108737
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, Xu W, Wu K, Zhang Q, Liu Y, Wu J
Virulence 2020 Dec;11(1):537-553
Virulence 2020 Dec;11(1):537-553
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis.
Chen W, Wang H, Zhu Z, Feng J, Chen L
Molecular therapy. Nucleic acids 2020 Dec 4;22:657-672
Molecular therapy. Nucleic acids 2020 Dec 4;22:657-672
Potential therapeutic role of fibroblast growth factor 21 in neurodegeneration: Evidence for ameliorating parkinsonism via silent information regulator 2 homolog 1 and implication for gene therapy.
Chen Y, Shen J, Qi G, Zha Q, Zhang C, Yao W, Gao X, Chen S
Neuropharmacology 2020 Dec 15;181:108335
Neuropharmacology 2020 Dec 15;181:108335
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Aras S, Purandare N, Gladyck S, Somayajulu-Nitu M, Zhang K, Wallace DC, Grossman LI
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Liu X, Meng L, Li X, Li D, Liu Q, Chen Y, Li X, Bu W, Sun H
International journal of oral science 2020 Dec 14;12(1):34
International journal of oral science 2020 Dec 14;12(1):34
CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway.
Li L, Xie P, Lin W, Liu J, Chen J, Guo Z, Bin C, An W, Zhang C, Zhan Y
Experimental cell research 2020 Dec 1;397(1):112341
Experimental cell research 2020 Dec 1;397(1):112341
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, Han L, Xin X, Wang H, Lin D, Peng F, Yu F, Zheng C, Shen C
Cell proliferation 2020 Aug;53(8):e12869
Cell proliferation 2020 Aug;53(8):e12869
Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways.
Zhang Q, Wang X, Cao S, Sun Y, He X, Jiang B, Yu Y, Duan J, Qiu F, Kang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110245
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110245
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy.
Bengoechea R, Findlay AR, Bhadra AK, Shao H, Stein KC, Pittman SK, Daw JA, Gestwicki JE, True HL, Weihl CC
The Journal of clinical investigation 2020 Aug 3;130(8):4470-4485
The Journal of clinical investigation 2020 Aug 3;130(8):4470-4485
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
Xie H, Li X, Yang W, Yu L, Jiang X, Chen Y, Shen Z, Li C, Gu M, Shi L
International journal of molecular sciences 2020 Aug 13;21(16)
International journal of molecular sciences 2020 Aug 13;21(16)
NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux.
Zhang YJ, Zhang M, Zhao X, Shi K, Ye M, Tian J, Guan S, Ying W, Qu X
Basic research in cardiology 2020 Aug 10;115(5):57
Basic research in cardiology 2020 Aug 10;115(5):57
Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.
Guo X, Zhang Y, Lu C, Qu F, Jiang X
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):714-724
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):714-724
Artemisinin Attenuated Atherosclerosis in High-Fat Diet-Fed ApoE-/- Mice by Promoting Macrophage Autophagy Through the AMPK/mTOR/ULK1 Pathway.
Cao Q, Du H, Fu X, Duan N, Liu C, Li X
Journal of cardiovascular pharmacology 2020 Apr;75(4):321-332
Journal of cardiovascular pharmacology 2020 Apr;75(4):321-332
Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
Koller EJ, Gonzalez De La Cruz E, Weinrich M, Williams T, Cruz PE, Ryu D, Golde TE, Sullivan PM, Lewis J, Borchelt DR, Chakrabarty P
Molecular neurobiology 2020 Apr;57(4):1986-2001
Molecular neurobiology 2020 Apr;57(4):1986-2001
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
Shi W, Ma H, Liu T, Yan D, Luo P, Zhai M, Tao J, Huo S, Guo J, Li C, Lin J, Zhang C, Li S, Lv J, Lin L
Journal of cellular and molecular medicine 2020 Apr;24(8):4748-4761
Journal of cellular and molecular medicine 2020 Apr;24(8):4748-4761
Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.
Liu K, Chen P, Lu J, Zhu Y, Xu Y, Liu Y, Liu J
Biological trace element research 2020 Apr;194(2):570-580
Biological trace element research 2020 Apr;194(2):570-580
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Chen Z, Liu L, Liu Y, Wang S, Zhang S, Dong R, Xu M, Ma Y, Wang J, Zhang Q, Wei P
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Wang N, Xu F, Lu S, Zhang N, Sun Y
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Chen HX, Liang FC, Gu P, Xu BL, Xu HJ, Wang WT, Hou JY, Xie DX, Chai XQ, An SJ
Cell death & disease 2020 Apr 27;11(4):288
Cell death & disease 2020 Apr 27;11(4):288
Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases.
Trejo-Lopez JA, Sorrentino ZA, Riffe CJ, Prokop S, Dickson DW, Yachnis AT, Giasson BI
Journal of neuropathology and experimental neurology 2020 Apr 1;79(4):407-418
Journal of neuropathology and experimental neurology 2020 Apr 1;79(4):407-418
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Zhang L, Zhou Y, Xia Q, Chen Y, Li J
Toxicology letters 2020 Apr 1;322:77-86
Toxicology letters 2020 Apr 1;322:77-86
Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
Yu M, Yang J, Gao X, Sun W, Liu S, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Qin A, Zhong T, Zou H, Wan X, Yao B, Zheng X, Yin D
Cell & bioscience 2019;9:13
Cell & bioscience 2019;9:13
Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.
Jiang J, Chen S, Li K, Zhang C, Tan Y, Deng Q, Chai Y, Wang X, Chen G, Feng K, Zhang L, Xie CM, Ma K
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):499-510
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):499-510
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
Guo Y, Pei X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Liu P, Li Y, Yang W, Liu D, Ji X, Chi T, Guo Z, Li L, Zou L
Oxidative medicine and cellular longevity 2019;2019:4032428
Oxidative medicine and cellular longevity 2019;2019:4032428
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
Wu X, Sun R, Wang H, Yang B, Wang F, Xu H, Chen S, Zhao R, Pi J, Xu Y
Oxidative medicine and cellular longevity 2019;2019:1038932
Oxidative medicine and cellular longevity 2019;2019:1038932
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
Wang H, Zhao Z, Lei S, Li S, Xiang Z, Wang X, Huang X, Xia G, Huang X
Cancer cell international 2019;19:7
Cancer cell international 2019;19:7
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
Ma S, Miao H, Luo Y, Sun Y, Tian X, Wang F, You C, Peng S, Tang G, Yang C, Sun W, Li S, Mao Y, Xu J, Xiao Y, Gong Y, Quan H, Xie C
International journal of biological sciences 2019;15(5):999-1009
International journal of biological sciences 2019;15(5):999-1009
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, Huo Z, Xu G
PloS one 2019;14(8):e0221104
PloS one 2019;14(8):e0221104
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
Chu C, Niu X, Ou X, Hu C
OncoTargets and therapy 2019;12:5661-5677
OncoTargets and therapy 2019;12:5661-5677
The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress.
Zheng Y, Tu J, Wang X, Yu Y, Li J, Jin Y, Wu J
OncoTargets and therapy 2019;12:10187-10198
OncoTargets and therapy 2019;12:10187-10198
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Qu L, Chen C, He W, Chen Y, Li Y, Wen Y, Zhou S, Jiang Y, Yang X, Zhang R, Shen L
American journal of translational research 2019;11(4):2042-2055
American journal of translational research 2019;11(4):2042-2055
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, Song Y, Luo J
American journal of translational research 2019;11(10):6680-6690
American journal of translational research 2019;11(10):6680-6690
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R
Frontiers in physiology 2019;10:735
Frontiers in physiology 2019;10:735
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Ye J, Xue M, Liu Y, Zhu S, Li Y, Liu X, Cai D, Rui J, Zhang L
Frontiers in pharmacology 2019;10:676
Frontiers in pharmacology 2019;10:676
Apigenin Combined With Gefitinib Blocks Autophagy Flux and Induces Apoptotic Cell Death Through Inhibition of HIF-1α, c-Myc, p-EGFR, and Glucose Metabolism in EGFR L858R+T790M-Mutated H1975 Cells.
Chen Z, Tian D, Liao X, Zhang Y, Xiao J, Chen W, Liu Q, Chen Y, Li D, Zhu L, Cai S
Frontiers in pharmacology 2019;10:260
Frontiers in pharmacology 2019;10:260
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Wang D, Guo H, Yang H, Wang D, Gao P, Wei W
Frontiers in pharmacology 2019;10:1238
Frontiers in pharmacology 2019;10:1238
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Zhang C, Zhan J, Zhao M, Dai H, Deng Y, Zhou W, Zhao L
Neurotoxicology 2019 Sep;74:74-80
Neurotoxicology 2019 Sep;74:74-80
Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate ameliorates pressure overload-induced cardiac hypertrophy and dysfunction through inhibiting autophagy.
Wang B, Shen D, Tang J, Li J, Xiao Y, Chen X, Cao C, Han D, Gao E, Zhao W, Zhang J, Chang J
Journal of cellular and molecular medicine 2019 Sep;23(9):6048-6059
Journal of cellular and molecular medicine 2019 Sep;23(9):6048-6059
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
Zhang X, Bu H, Jiang Y, Sun G, Jiang R, Huang X, Duan H, Huang Z, Wu Q
Molecular medicine reports 2019 Sep;20(3):2867-2874
Molecular medicine reports 2019 Sep;20(3):2867-2874
Protective role of thymoquinone in sepsis-induced liver injury in BALB/c mice.
Wang F, Lei X, Zhao Y, Yu Q, Li Q, Zhao H, Pei Z
Experimental and therapeutic medicine 2019 Sep;18(3):1985-1992
Experimental and therapeutic medicine 2019 Sep;18(3):1985-1992
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Liang J, Zhou F, Xiong X, Zhang X, Li S, Li X, Gao M, Li Y
Aging 2019 Sep 6;11(17):7036-7050
Aging 2019 Sep 6;11(17):7036-7050
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, Lian S
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
Xu D, Jiang X, He H, Liu D, Yang L, Chen H, Wu L, Geng G, Li Q
Life sciences 2019 Sep 1;232:116639
Life sciences 2019 Sep 1;232:116639
Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine.
Zhou Y, Tao X, Wang Z, Feng L, Wang L, Liu X, Pan R, Liao Y, Chang Q
International journal of molecular sciences 2019 Sep 1;20(17)
International journal of molecular sciences 2019 Sep 1;20(17)
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Xu WN, Yang RZ, Zheng HL, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity.
Li CF, Pan YK, Gao Y, Shi F, Wang YC, Sun XQ
Apoptosis : an international journal on programmed cell death 2019 Oct;24(9-10):812-825
Apoptosis : an international journal on programmed cell death 2019 Oct;24(9-10):812-825
Krüppel‑like factor 4 ameliorates diabetic kidney disease by activating autophagy via the mTOR pathway.
Gong J, Zhan H, Li Y, Zhang W, Jin J, He Q
Molecular medicine reports 2019 Oct;20(4):3240-3248
Molecular medicine reports 2019 Oct;20(4):3240-3248
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Jin J, Gong J, Zhao L, Zhang H, He Q, Jiang X
Journal of diabetes 2019 Oct;11(10):826-836
Journal of diabetes 2019 Oct;11(10):826-836
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Sacino AN, Prokop S, Walsh MA, Adamson J, Subramony SH, Krans A, Todd PK, Giasson BI, Yachnis AT
Acta neuropathologica communications 2019 Oct 30;7(1):158
Acta neuropathologica communications 2019 Oct 30;7(1):158
Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome.
Krans A, Skariah G, Zhang Y, Bayly B, Todd PK
Acta neuropathologica communications 2019 Oct 30;7(1):152
Acta neuropathologica communications 2019 Oct 30;7(1):152
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Lu Q, Tan S, Gu W, Li F, Hua W, Zhang S, Chen F, Tang L
Journal of ethnopharmacology 2019 Oct 28;243:112089
Journal of ethnopharmacology 2019 Oct 28;243:112089
Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells.
Hu B, Song W, Tang Y, Shi M, Li H, Yu D
Animals : an open access journal from MDPI 2019 Oct 21;9(10)
Animals : an open access journal from MDPI 2019 Oct 21;9(10)
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
Wei W, Lu M, Lan X, Liu N, Wang H, Du J, Sun T, Li Y, Yu J
Neuroscience letters 2019 Oct 15;711:134415
Neuroscience letters 2019 Oct 15;711:134415
B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma.
Yu S, Wang X, Dou N, Zhou J, Gao Y, Li Y
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Nov;49(11):1329-1340
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Nov;49(11):1329-1340
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Wang Z, Zhang M, Shan R, Wang YJ, Chen J, Huang J, Sun LQ, Zhou WB
Oncology reports 2019 Nov;42(5):1915-1923
Oncology reports 2019 Nov;42(5):1915-1923
Mitophagy protects against statin-mediated skeletal muscle toxicity.
Ramesh M, Campos JC, Lee P, Song Y, Hernandez G, Sin J, Tucker KC, Saadaeijahromi H, Gurney M, Ferreira JCB, Andres AM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):11857-11869
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):11857-11869
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
Kuang M, Li L, Li C, Wang G
Cell stress & chaperones 2019 Nov;24(6):1115-1125
Cell stress & chaperones 2019 Nov;24(6):1115-1125
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Huo T, Jia Y, Yin C, Luo X, Zhao J, Wang Z, Lv P
Brain research bulletin 2019 Nov;153:305-313
Brain research bulletin 2019 Nov;153:305-313
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Hussain Mangi M, Yao J, Dong H, Yang L, Zhou X
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
Xu WN, Zheng HL, Yang RZ, Liu T, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Shen J, Wang J, Du J, Wang L, Zhou X, Chang X, Li Z, Zhai X, Zuo D, Wu Y
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Toxicology and applied pharmacology 2019 Nov 15;383:114781
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Sun J, Feng Y, Wang Y, Ji Q, Cai G, Shi L, Wang Y, Huang Y, Zhang J, Li Q
International journal of oncology 2019 May;54(5):1601-1612
International journal of oncology 2019 May;54(5):1601-1612
Dihydroartemisinin, an antimalarial drug, induces absent in melanoma 2 inflammasome activation and autophagy in human hepatocellular carcinoma HepG2215 cells.
Shi X, Wang L, Ren L, Li J, Li S, Cui Q, Li S
Phytotherapy research : PTR 2019 May;33(5):1413-1425
Phytotherapy research : PTR 2019 May;33(5):1413-1425
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Dong H, Hussain Mangi M, Ni J, Yang L, Zhou X
Cells 2019 May 26;8(5)
Cells 2019 May 26;8(5)
Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.
Dhillon JS, Trejo-Lopez JA, Riffe C, Levites Y, Sacino AN, Borchelt DR, Yachnis AY, Giasson BI
Acta neuropathologica communications 2019 May 20;7(1):80
Acta neuropathologica communications 2019 May 20;7(1):80
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, Zhang L, Lei Y, Shen L, Zhang F
Cell reports 2019 May 14;27(7):2075-2091.e5
Cell reports 2019 May 14;27(7):2075-2091.e5
Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy.
Wang Y, Meng C, Zhang J, Wu J, Zhao J
International immunopharmacology 2019 Mar;68:234-241
International immunopharmacology 2019 Mar;68:234-241
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Gu X, Han M, Du Y, Wu Y, Xu Y, Zhou X, Ye D, Wang HL
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Carfilzomib enhances cisplatin-induced apoptosis in SK-N-BE(2)-M17 human neuroblastoma cells.
Lee SI, Jeong YJ, Yu AR, Kwak HJ, Cha JY, Kang I, Yeo EJ
Scientific reports 2019 Mar 25;9(1):5039
Scientific reports 2019 Mar 25;9(1):5039
Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte.
Jin J, Shi Y, Gong J, Zhao L, Li Y, He Q, Huang H
Stem cell research & therapy 2019 Mar 15;10(1):95
Stem cell research & therapy 2019 Mar 15;10(1):95
LncRNA ENST00000453774.1 contributes to oxidative stress defense dependent on autophagy mediation to reduce extracellular matrix and alleviate renal fibrosis.
Xiao X, Yuan Q, Chen Y, Huang Z, Fang X, Zhang H, Peng L, Xiao P
Journal of cellular physiology 2019 Jun;234(6):9130-9143
Journal of cellular physiology 2019 Jun;234(6):9130-9143
miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis.
Wu J, Kuang L, Chen C, Yang J, Zeng WN, Li T, Chen H, Huang S, Fu Z, Li J, Liu R, Ni Z, Chen L, Yang L
Biomaterials 2019 Jun;206:87-100
Biomaterials 2019 Jun;206:87-100
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Arhzaouy K, Papadopoulos C, Schulze N, Pittman SK, Meyer H, Weihl CC
Autophagy 2019 Jun;15(6):1082-1099
Autophagy 2019 Jun;15(6):1082-1099
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer NJ, Ma R, Nakayama L, Monbureau M, Defensor E, Schüle B, Shamloo M, Melki R, Gitler AD
Acta neuropathologica 2019 Jun;137(6):961-980
Acta neuropathologica 2019 Jun;137(6):961-980
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
Wang Z, Yang X, Liu C, Li X, Zhang B, Wang B, Zhang Y, Song C, Zhang T, Liu M, Liu B, Ren M, Jiang H, Zou J, Liu X, Zhang H, Zhu WG, Yin Y, Zhang Z, Gu W, Luo J
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Cui C, Li Z, Wu D
Biological research 2019 Jun 13;52(1):32
Biological research 2019 Jun 13;52(1):32
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Jiang R, Zhou Z, Liao Y, Yang F, Cheng Y, Huang J, Wang J, Chen H, Zhu T, Chao J
Toxicology letters 2019 Jun 1;307:26-40
Toxicology letters 2019 Jun 1;307:26-40
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Wu D, Zhong P, Wang J, Wang H
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Zhu J, Li J, Wang X, Feng X, Li Y
The new microbiologica 2019 Jul;42(3):161-165
The new microbiologica 2019 Jul;42(3):161-165
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
Xu G, Wang X, Yu H, Wang C, Liu Y, Zhao R, Zhang G
Human & experimental toxicology 2019 Jul;38(7):794-802
Human & experimental toxicology 2019 Jul;38(7):794-802
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
Yang L, Qiu T, Yao X, Jiang L, Wei S, Pei P, Wang Z, Bai J, Liu X, Yang G, Liu S, Sun X
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
SQSTM1/p62 loss reverses the inhibitory effect of sunitinib on autophagy independent of AMPK signaling.
Hou B, Wang G, Gao Q, Wei Y, Zhang C, Wang Y, Huo Y, Yang H, Jiang X, Xi Z
Scientific reports 2019 Jul 31;9(1):11087
Scientific reports 2019 Jul 31;9(1):11087
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Yin F, Yan J, Zhao Y, Guo KJ, Zhang ZL, Li AP, Meng CY, Guo L
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
iRoot BP Plus promotes osteo/odontogenic differentiation of bone marrow mesenchymal stem cells via MAPK pathways and autophagy.
Lu J, Li Z, Wu X, Chen Y, Yan M, Ge X, Yu J
Stem cell research & therapy 2019 Jul 29;10(1):222
Stem cell research & therapy 2019 Jul 29;10(1):222
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
Qian L, Zhu K, Lin Y, An L, Huang F, Yao Y, Ren L
Cell biology international 2019 Jul 24;
Cell biology international 2019 Jul 24;
ERβ promotes Aβ degradation via the modulation of autophagy.
Wei Y, Zhou J, Wu J, Huang J
Cell death & disease 2019 Jul 22;10(8):565
Cell death & disease 2019 Jul 22;10(8):565
Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.
Khan N, Yılmaz S, Aksoy S, Uzel A, Tosun Ç, Kirmizibayrak PB, Bedir E
Chemico-biological interactions 2019 Jul 1;307:167-178
Chemico-biological interactions 2019 Jul 1;307:167-178
Berberine ameliorates oxidative stress-induced apoptosis by modulating ER stress and autophagy in human nucleus pulposus cells.
Luo R, Liao Z, Song Y, Yin H, Zhan S, Li G, Ma L, Lu S, Wang K, Li S, Zhang Y, Yang C
Life sciences 2019 Jul 1;228:85-97
Life sciences 2019 Jul 1;228:85-97
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
Chen Z, Jiang Q, Zhu P, Chen Y, Xie X, Du Z, Jiang L, Tang W
The Prostate 2019 Jan;79(1):44-53
The Prostate 2019 Jan;79(1):44-53
Alterations of autophagy in knee cartilage by treatment with treadmill exercise in a rat osteoarthritis model.
Zhang X, Yang Y, Li X, Zhang H, Gang Y, Bai L
International journal of molecular medicine 2019 Jan;43(1):336-344
International journal of molecular medicine 2019 Jan;43(1):336-344
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, Li S, Wu L, Feng J, Xu S, Wang W, Lu X, Fan X, Mo W, Zhou Y, Zhao Y, Guo C
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.
Schweitzer GG, Collier SL, Chen Z, McCommis KS, Pittman SK, Yoshino J, Matkovich SJ, Hsu FF, Chrast R, Eaton JM, Harris TE, Weihl CC, Finck BN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):652-667
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):652-667
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J
Free radical biology & medicine 2019 Jan;130:576-591
Free radical biology & medicine 2019 Jan;130:576-591
AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells.
Zhang Z, Zhang M, Liu H, Yin W
Journal of cellular biochemistry 2019 Jan;120(1):756-767
Journal of cellular biochemistry 2019 Jan;120(1):756-767
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Zhang WX, He BM, Wu Y, Qiao JF, Peng ZY
Life sciences 2019 Jan 15;217:8-15
Life sciences 2019 Jan 15;217:8-15
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Wu J, Zhou Y, Yuan Z, Yi J, Chen J, Wang N, Tian Y
Toxins 2019 Jan 15;11(1)
Toxins 2019 Jan 15;11(1)
Autophagy protects against redox-active trace metal-induced cell death in rabbit synovial fibroblasts through Toll-like receptor 4 activation.
Alsousi AA, Igwe OJ
Experimental cell research 2019 Jan 1;374(1):19-28
Experimental cell research 2019 Jan 1;374(1):19-28
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
Taurine protected As2O3-induced the activation of hepatic stellate cells through inhibiting PPARα-autophagy pathway.
Wang Z, Tao Y, Qiu T, Yao X, Jiang L, Wang N, Wei S, Jia X, Pei P, Yang G, Liu X, Liu S, Sun X
Chemico-biological interactions 2019 Feb 25;300:123-130
Chemico-biological interactions 2019 Feb 25;300:123-130
Anti-Invasion and Antiangiogenic Effects of Stellettin B through Inhibition of the Akt/Girdin Signaling Pathway and VEGF in Glioblastoma Cells.
Cheng SY, Chen NF, Lin PY, Su JH, Chen BH, Kuo HM, Sung CS, Sung PJ, Wen ZH, Chen WF
Cancers 2019 Feb 14;11(2)
Cancers 2019 Feb 14;11(2)
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Pan Y, Li Z, Wang Y, Yan M, Wu J, Beharee RG, Yu J
Journal of cellular physiology 2019 Feb 14;
Journal of cellular physiology 2019 Feb 14;
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
Yonsei medical journal 2019 Dec;60(12):1195-1202
Yonsei medical journal 2019 Dec;60(12):1195-1202
Loss of HMBOX1 promotes LPS-induced apoptosis and inhibits LPS-induced autophagy of vascular endothelial cells in mouse.
Ma H, Su L, He X, Miao J
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):946-957
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):946-957
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, Yang L
Journal of medicinal food 2019 Dec;22(12):1271-1279
Journal of medicinal food 2019 Dec;22(12):1271-1279
FAM134B improves preadipocytes differentiation by enhancing mitophagy.
Cai M, Zhao J, Liu Q, Wang X, Wang Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Dec;1864(12):158508
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Dec;1864(12):158508
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Wang N, Yang B, Muhetaer G, Wang S, Zheng Y, Lu J, Li M, Zhang F, Situ H, Lin Y, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition.
Qin S, Jiang C, Gao J
Biomedical reports 2019 Dec;11(6):241-252
Biomedical reports 2019 Dec;11(6):241-252
Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells.
Wang J, Li L, Wang J, Song L, Tan N, Wang Z
Cells 2019 Dec 7;8(12)
Cells 2019 Dec 7;8(12)
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress.
You Z, Jiang WX, Qin LY, Gong Z, Wan W, Li J, Wang Y, Zhang H, Peng C, Zhou T, Tang C, Liu W
Nature communications 2019 Dec 19;10(1):5792
Nature communications 2019 Dec 19;10(1):5792
A New Possible Mechanism by Which Punicalagin Protects against Liver Injury Induced by Type 2 Diabetes Mellitus: Upregulation of Autophagy via the Akt/FoxO3a Signaling Pathway.
Zhang Y, Cao Y, Chen J, Qin H, Yang L
Journal of agricultural and food chemistry 2019 Dec 18;67(50):13948-13959
Journal of agricultural and food chemistry 2019 Dec 18;67(50):13948-13959
Solanesol derived therapeutic carriers for anticancer drug delivery.
Xiong Y, Hou T, Liu L, Peng W, Wang C, Lu Y, Wang S, Shi J, Song S
International journal of pharmaceutics 2019 Dec 15;572:118823
International journal of pharmaceutics 2019 Dec 15;572:118823
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, Feng J
Life sciences 2019 Dec 15;239:117020
Life sciences 2019 Dec 15;239:117020
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, Sands N, O'Connell D, Restrepo-Vassalli S, Chai B, Nemecio D, Punj V, Akbari O, Idos GE, Mumenthaler SM, Wu N, Martin SE, Hagiya A, Hicks J, Cui H, Liang C
Nature communications 2019 Dec 12;10(1):5681
Nature communications 2019 Dec 12;10(1):5681
Zearalenone induces NLRP3-dependent pyroptosis via activation of NF-κB modulated by autophagy in INS-1 cells.
Wang X, Jiang L, Shi L, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Wang Y, Liu X
Toxicology 2019 Dec 1;428:152304
Toxicology 2019 Dec 1;428:152304
Quercetin shows anti-tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway.
Wu L, Li J, Liu T, Li S, Feng J, Yu Q, Zhang J, Chen J, Zhou Y, Ji J, Chen K, Mao Y, Wang F, Dai W, Fan X, Wu J, Guo C
Cancer medicine 2019 Aug;8(10):4806-4820
Cancer medicine 2019 Aug;8(10):4806-4820
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
Wen J, Xu B, Sun Y, Lian M, Li Y, Lin Y, Chen D, Diao Y, Almoiliqy M, Wang L
Pharmacological research 2019 Aug;146:104308
Pharmacological research 2019 Aug;146:104308
SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function.
Wang P, Wang L, Lu J, Hu Y, Wang Q, Li Z, Cai S, Liang L, Guo K, Xie J, Wang J, Lan R, Shen J, Liu P
Journal of molecular and cellular cardiology 2019 Aug;133:125-137
Journal of molecular and cellular cardiology 2019 Aug;133:125-137
Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice.
Chen Z, Yang D, Jiang X, Tian L, Sun J, Tian D, Bai W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Aug;130:1-11
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Aug;130:1-11
TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ.
Lu H, Xiao J, Ke C, Ni X, Xiu R, Tian Q, Pan H, Zou L, Wang F, Ma T, Ji X, Yuan P, Liu L, Zhang J, Jia W, Duan Q, Zhu F
Cell death & disease 2019 Aug 5;10(8):583
Cell death & disease 2019 Aug 5;10(8):583
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Li T, Wen L, Cheng B
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Liu H, Sun Y, Zhang Y, Yang G, Guo L, Zhao Y, Pei Z
Inflammation 2019 Apr;42(2):516-525
Inflammation 2019 Apr;42(2):516-525
Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease.
Barriocanal-Casado E, Hidalgo-Gutiérrez A, Raimundo N, González-García P, Acuña-Castroviejo D, Escames G, López LC
EBioMedicine 2019 Apr;42:511-523
EBioMedicine 2019 Apr;42:511-523
Taurine improves low-level inorganic arsenic-induced insulin resistance by activating PPARγ-mTORC2 signalling and inhibiting hepatic autophagy.
Gao N, Yao X, Jiang L, Yang L, Qiu T, Wang Z, Pei P, Yang G, Liu X, Sun X
Journal of cellular physiology 2019 Apr;234(4):5143-5152
Journal of cellular physiology 2019 Apr;234(4):5143-5152
Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
Li L, Li L, Zhou X, Yu Y, Li Z, Zuo D, Wu Y
Nanotoxicology 2019 Apr;13(3):369-391
Nanotoxicology 2019 Apr;13(3):369-391
Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy.
Sun CY, Nie J, Zheng ZL, Zhao J, Wu LM, Zhu Y, Su ZQ, Zheng GJ, Feng B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108647
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108647
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z
Molecular cancer 2019 Apr 5;18(1):82
Molecular cancer 2019 Apr 5;18(1):82
The regulatory role of COX-2 in the interaction between Cr(VI)-induced endoplasmic reticulum stress and autophagy in DF-1 cells.
Chen P, Geng N, Zhou D, Zhu Y, Xu Y, Liu K, Liu Y, Liu J
Ecotoxicology and environmental safety 2019 Apr 15;170:112-119
Ecotoxicology and environmental safety 2019 Apr 15;170:112-119
Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway.
Yang J, Xu J, Han X, Wang H, Zhang Y, Dong J, Deng Y, Wang J
Frontiers in physiology 2018;9:1315
Frontiers in physiology 2018;9:1315
Activation of Cyclooxygenase-2 by ATF4 During Endoplasmic Reticulum Stress Regulates Kidney Podocyte Autophagy Induced by Lupus Nephritis.
Jin J, Zhao L, Zou W, Shen W, Zhang H, He Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):753-764
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):753-764
3-methyadenine attenuates chloroform-induced hepatotoxicity via autophagy activation.
Wang L, Li X, Chen C
Biomedical research (Tokyo, Japan) 2018;39(2):87-94
Biomedical research (Tokyo, Japan) 2018;39(2):87-94
Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia.
Wang Y, Jiang SW, Liu X, Niu L, Ge XL, Zhang JC, Wang HR, Fei AH, Gao CJ, Pan SM
Oxidative medicine and cellular longevity 2018;2018:4612727
Oxidative medicine and cellular longevity 2018;2018:4612727
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Mo W, Wang C, Li J, Chen K, Xia Y, Li S, Xu L, Lu X, Wang W, Guo C
Gastroenterology research and practice 2018;2018:2824139
Gastroenterology research and practice 2018;2018:2824139
Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis.
Lin HH, Chung Y, Cheng CT, Ouyang C, Fu Y, Kuo CY, Chi KK, Sadeghi M, Chu P, Kung HJ, Li CF, Limesand KH, Ann DK
Autophagy 2018;14(9):1481-1498
Autophagy 2018;14(9):1481-1498
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Han B, Zhang Y, Zhang Y, Bai Y, Chen X, Huang R, Wu F, Leng S, Chao J, Zhang JH, Hu G, Yao H
Autophagy 2018;14(7):1164-1184
Autophagy 2018;14(7):1164-1184
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, Zhang S, Gao H, Wang P, Zhang Z, Luo J, Li Z
Autophagy 2018;14(2):336-346
Autophagy 2018;14(2):336-346
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, Lv Y, Liu Q, Guo C, Zhou Y
Drug design, development and therapy 2018;12:4067-4082
Drug design, development and therapy 2018;12:4067-4082
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, Wang W, Lu X, Liu T, Guo C
Drug design, development and therapy 2018;12:1837-1853
Drug design, development and therapy 2018;12:1837-1853
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Zhang J, Liu L, Xue Y, Ma Y, Liu X, Li Z, Li Z, Liu Y
Frontiers in molecular neuroscience 2018;11:92
Frontiers in molecular neuroscience 2018;11:92
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, Li X, Xie C, Zhong C, Fu S
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Liang S, Jin J, Shen X, Jiang X, Li Y, He Q
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Comprehensive anti-tumor effect of Brusatol through inhibition of cell viability and promotion of apoptosis caused by autophagy via the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.
Ye R, Dai N, He Q, Guo P, Xiang Y, Zhang Q, Hong Z, Zhang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:962-973
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:962-973
Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.
Ayers JI, Riffe CJ, Sorrentino ZA, Diamond J, Fagerli E, Brooks M, Galaleldeen A, Hart PJ, Giasson BI
Journal of virology 2018 Sep 15;92(18)
Journal of virology 2018 Sep 15;92(18)
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, Li W
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation.
Xin D, Chu X, Bai X, Ma W, Yuan H, Qiu J, Liu C, Li T, Zhou X, Chen W, Liu D, Wang Z
Brain, behavior, and immunity 2018 Oct;73:222-234
Brain, behavior, and immunity 2018 Oct;73:222-234
NLRC5 and autophagy combined as possible predictors in patients with endometriosis.
Zhan L, Yao S, Sun S, Su Q, Li J, Wei B
Fertility and sterility 2018 Oct;110(5):949-956
Fertility and sterility 2018 Oct;110(5):949-956
mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
Wan W, You Z, Zhou L, Xu Y, Peng C, Zhou T, Yi C, Shi Y, Liu W
Molecular cell 2018 Oct 18;72(2):303-315.e6
Molecular cell 2018 Oct 18;72(2):303-315.e6
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
Yang X, Chen XJ, Yang Z, Xi YB, Wang L, Wu Y, Yan YB, Rao Y
Journal of medicinal chemistry 2018 Oct 11;61(19):8693-8706
Journal of medicinal chemistry 2018 Oct 11;61(19):8693-8706
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Zhao Y, Li Y, Wang J, Manthari RK, Wang J
Archives of toxicology 2018 Nov;92(11):3277-3289
Archives of toxicology 2018 Nov;92(11):3277-3289
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Cui Y, Zhang Z, Zhang B, Zhao L, Hou C, Zeng Q, Nie J, Yu J, Zhao Y, Gao T, Wang A, Liu H
Toxicology letters 2018 Nov;297:24-33
Toxicology letters 2018 Nov;297:24-33
Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Guo S, Liang X, Guo M, Zhang X, Li Z
International journal of biological macromolecules 2018 Nov;119:669-676
International journal of biological macromolecules 2018 Nov;119:669-676
Mutant UBQLN2P497H in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
Chen T, Huang B, Shi X, Gao L, Huang C
Acta neuropathologica communications 2018 Nov 8;6(1):122
Acta neuropathologica communications 2018 Nov 8;6(1):122
In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.
Uenaka T, Satake W, Cha PC, Hayakawa H, Baba K, Jiang S, Kobayashi K, Kanagawa M, Okada Y, Mochizuki H, Toda T
Human molecular genetics 2018 Nov 15;27(22):3974-3985
Human molecular genetics 2018 Nov 15;27(22):3974-3985
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury.
Wang Y, Tang C, Cai J, Chen G, Zhang D, Zhang Z, Dong Z
Cell death & disease 2018 Nov 1;9(11):1113
Cell death & disease 2018 Nov 1;9(11):1113
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, Gu Q, Liu C, Liang M, Guo X, Liu P, Li M
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
Sheng Y, Song Y, Li Z, Wang Y, Lin H, Cheng H, Zhou R
Cell death and differentiation 2018 May;25(5):918-934
Cell death and differentiation 2018 May;25(5):918-934
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR 3rd, Jones KA
PLoS pathogens 2018 May;14(5):e1007071
PLoS pathogens 2018 May;14(5):e1007071
Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites.
Thinon E, Fernandez JP, Molina H, Hang HC
Journal of proteome research 2018 May 4;17(5):1907-1922
Journal of proteome research 2018 May 4;17(5):1907-1922
Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells.
Yang G, Bai Y, Wu X, Sun X, Sun M, Liu X, Yao X, Zhang C, Chu Q, Jiang L, Wang S
Chemico-biological interactions 2018 May 25;288:24-31
Chemico-biological interactions 2018 May 25;288:24-31
Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion.
Li Z, Wang G, Feng D, Zu G, Li Y, Shi X, Zhao Y, Jing H, Ning S, Le W, Yao J, Tian X
Cell death & disease 2018 May 1;9(5):483
Cell death & disease 2018 May 1;9(5):483
A novel stromal lncRNA signature reprograms fibroblasts to promote the growth of oral squamous cell carcinoma via LncRNA-CAF/interleukin-33.
Ding L, Ren J, Zhang D, Li Y, Huang X, Hu Q, Wang H, Song Y, Ni Y, Hou Y
Carcinogenesis 2018 Mar 8;39(3):397-406
Carcinogenesis 2018 Mar 8;39(3):397-406
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
Gao M, Li C, Xu M, Liu Y, Liu S
Toxicology letters 2018 Mar 1;284:195-204
Toxicology letters 2018 Mar 1;284:195-204
TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.
Lee Y, Jonson PH, Sarparanta J, Palmio J, Sarkar M, Vihola A, Evilä A, Suominen T, Penttilä S, Savarese M, Johari M, Minot MC, Hilton-Jones D, Maddison P, Chinnery P, Reimann J, Kornblum C, Kraya T, Zierz S, Sue C, Goebel H, Azfer A, Ralston SH, Hackman P, Bucelli RC, Taylor JP, Weihl CC, Udd B
The Journal of clinical investigation 2018 Mar 1;128(3):1164-1177
The Journal of clinical investigation 2018 Mar 1;128(3):1164-1177
Prodigiosin stimulates endoplasmic reticulum stress and induces autophagic cell death in glioblastoma cells.
Cheng SY, Chen NF, Kuo HM, Yang SN, Sung CS, Sung PJ, Wen ZH, Chen WF
Apoptosis : an international journal on programmed cell death 2018 Jun;23(5-6):314-328
Apoptosis : an international journal on programmed cell death 2018 Jun;23(5-6):314-328
A tumor-activatable particle with antimetastatic potential in breast cancer via inhibiting the autophagy-dependent disassembly of focal adhesion.
Wang Y, Yin S, Zhang L, Shi K, Tang J, Zhang Z, He Q
Biomaterials 2018 Jun;168:1-9
Biomaterials 2018 Jun;168:1-9
Association of HMGB1, BRCA1 and P62 expression in ovarian cancer and chemotherapy sensitivity.
Li S, Wei Y
Oncology letters 2018 Jun;15(6):9572-9576
Oncology letters 2018 Jun;15(6):9572-9576
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Li C, Zhang J, Xu H, Chang M, Lv C, Xue W, Song Z, Zhang L, Zhang X, Tian X
Neuropharmacology 2018 Jun;135:151-162
Neuropharmacology 2018 Jun;135:151-162
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, Chen S, Shi A, Chan DC, Song Z
Cell reports 2018 Jun 5;23(10):2989-3005
Cell reports 2018 Jun 5;23(10):2989-3005
Potentiating bacterial cancer therapy using hydroxychloroquine liposomes.
Wang Y, Zhou Z, Chen W, Qin M, Zhang Z, Gong T, Sun X
Journal of controlled release : official journal of the Controlled Release Society 2018 Jun 28;280:39-50
Journal of controlled release : official journal of the Controlled Release Society 2018 Jun 28;280:39-50
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Liu H, Wang L, Zeng Q, Zhao L, Cui Y, Hou C, Zhang B, Zhang Z, Zhang S, Chen X, Wang A
Environmental toxicology 2018 Jun 19;
Environmental toxicology 2018 Jun 19;
Tripterygium glycoside protects against puromycin amino nucleoside‑induced podocyte injury by upregulating autophagy.
Gong J, Jin J, Zhao L, Li Y, Li Y, He Q
International journal of molecular medicine 2018 Jul;42(1):115-122
International journal of molecular medicine 2018 Jul;42(1):115-122
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
p38δ MAPK regulates aggresome biogenesis by phosphorylating SQSTM1 in response to proteasomal stress.
Zhang C, Gao J, Li M, Deng Y, Jiang C
Journal of cell science 2018 Jul 26;131(14)
Journal of cell science 2018 Jul 26;131(14)
Effects of n-3PUFAs on autophagy and inflammation of hypothalamus and body weight in mice.
Fang X, Ge K, Song C, Ge Y, Zhang J
Biochemical and biophysical research communications 2018 Jul 2;501(4):927-932
Biochemical and biophysical research communications 2018 Jul 2;501(4):927-932
Chronic intermittent hypobaric hypoxia protects vascular endothelium by ameliorating autophagy in metabolic syndrome rats.
Cui F, Guan Y, Guo J, Tian YM, Hu HF, Zhang XJ, Zhang Y
Life sciences 2018 Jul 15;205:145-154
Life sciences 2018 Jul 15;205:145-154
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
Hu X, Mei S, Meng W, Xue S, Jiang L, Yang Y, Hui L, Chen Y, Guan MX
Cancer letters 2018 Jul 1;425:1-12
Cancer letters 2018 Jul 1;425:1-12
Pancreatic islet-autonomous effect of arsenic on insulin secretion through endoplasmic reticulum stress-autophagy pathway.
Wu W, Yao X, Jiang L, Zhang Q, Bai J, Qiu T, Yang L, Gao N, Yang G, Liu X, Chen M, Sun X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Jan;111:19-26
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Jan;111:19-26
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Wei W, An XR, Jin SJ, Li XX, Xu M
Scientific reports 2018 Jan 8;8(1):9
Scientific reports 2018 Jan 8;8(1):9
Autophagy dysregulation caused by ApoM deficiency plays an important role in liver lipid metabolic disorder.
Zhang X, Zhang P, Gao J, Huang Q
Biochemical and biophysical research communications 2018 Jan 22;495(4):2643-2648
Biochemical and biophysical research communications 2018 Jan 22;495(4):2643-2648
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
Xu H, Sun L, Zheng Y, Yu S, Ou-Yang J, Han H, Dai X, Yu X, Li M, Lan Q
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Wang L, Ye N, Lian X, Peng F, Zhang H, Gong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells.
He X, Yuan W, Li Z, Hou Y, Liu F, Feng J
Toxicology letters 2018 Feb;283:58-68
Toxicology letters 2018 Feb;283:58-68
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M, Wang F, Ren H, Cui H, Jiang A, Wang Z, Zou M, Ji Y
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
Díaz-Casado ME, Rusanova I, Aranda P, Fernández-Ortiz M, Sayed RKA, Fernández-Gil BI, Hidalgo-Gutiérrez A, Escames G, López LC, Acuña-Castroviejo D
Zebrafish 2018 Feb;15(1):15-26
Zebrafish 2018 Feb;15(1):15-26
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Xiao Y, Zhou Y, Lu Y, Zhou K, Cai W
Cell death & disease 2018 Feb 7;9(2):160
Cell death & disease 2018 Feb 7;9(2):160
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
Li Z, Zhu S, Huang L, Shang M, Yu C, Zhu H, Han D, Huang H, Yu X, Li X
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
Wang W, Chen D, Zhu K
Journal of experimental & clinical cancer research : CR 2018 Feb 23;37(1):37
Journal of experimental & clinical cancer research : CR 2018 Feb 23;37(1):37
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells.
Li CF, Sun JX, Gao Y, Shi F, Pan YK, Wang YC, Sun XQ
Cell death & disease 2018 Feb 2;9(2):147
Cell death & disease 2018 Feb 2;9(2):147
LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation.
Du Y, Duan T, Feng Y, Liu Q, Lin M, Cui J, Wang RF
The EMBO journal 2018 Feb 1;37(3):351-366
The EMBO journal 2018 Feb 1;37(3):351-366
Pre-treatment with angiotensin-(1-7) inhibits tumor growth via autophagy by downregulating PI3K/Akt/mTOR signaling in human nasopharyngeal carcinoma xenografts.
Lin YT, Wang HC, Chuang HC, Hsu YC, Yang MY, Chien CY
Journal of molecular medicine (Berlin, Germany) 2018 Dec;96(12):1407-1418
Journal of molecular medicine (Berlin, Germany) 2018 Dec;96(12):1407-1418
Autophagy participates in innate immune defense in lamprey.
Luo L, Lu J, Wang Q, Chen S, Xu A, Yuan S
Fish & shellfish immunology 2018 Dec;83:416-424
Fish & shellfish immunology 2018 Dec;83:416-424
FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.
Meng X, Liu X, Guo X, Jiang S, Chen T, Hu Z, Liu H, Bai Y, Xue M, Hu R, Sun SC, Liu X, Zhou P, Huang X, Wei L, Yang W, Xu C
Nature 2018 Dec;564(7734):130-135
Nature 2018 Dec;564(7734):130-135
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
O-GlcNAc-modified SNAP29 inhibits autophagy-mediated degradation via the disturbed SNAP29-STX17-VAMP8 complex and exacerbates myocardial injury in type I diabetic rats.
Huang L, Yuan P, Yu P, Kong Q, Xu Z, Yan X, Shen Y, Yang J, Wan R, Hong K, Tang Y, Hu J
International journal of molecular medicine 2018 Dec;42(6):3278-3290
International journal of molecular medicine 2018 Dec;42(6):3278-3290
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Li Y, Fu S, Li E, Sun X, Xu H, Meng Y, Wang X, Chen Y, Xie C, Geng S, Wu J, Zhong C, Xu P
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration.
Sorrentino ZA, Xia Y, Funk C, Riffe CJ, Rutherford NJ, Ceballos Diaz C, Sacino AN, Price ND, Golde TE, Giasson BI, Chakrabarty P
Neurobiology of disease 2018 Dec;120:98-106
Neurobiology of disease 2018 Dec;120:98-106
Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice.
Zhang X, Liu H, Hao Y, Xu L, Zhang T, Liu Y, Guo L, Zhu L, Pei Z
Lipids in health and disease 2018 Dec 8;17(1):279
Lipids in health and disease 2018 Dec 8;17(1):279
Attenuating Spinal Cord Injury by Conditioned Medium from Bone Marrow Mesenchymal Stem Cells.
Tsai MJ, Liou DY, Lin YR, Weng CF, Huang MC, Huang WC, Tseng FW, Cheng H
Journal of clinical medicine 2018 Dec 25;8(1)
Journal of clinical medicine 2018 Dec 25;8(1)
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Hsiao CJ, Chang CH, Ibrahim RB, Lin IH, Wang CH, Wang WJ, Tsai JW
Journal of cell science 2018 Dec 17;131(24)
Journal of cell science 2018 Dec 17;131(24)
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S
The Science of the total environment 2018 Dec 15;645:363-371
The Science of the total environment 2018 Dec 15;645:363-371
Inhibition of acetaminophen-induced hepatotoxicity in mice by exogenous thymosinβ4 treatment.
Wang L, Li X, Chen C
International immunopharmacology 2018 Aug;61:20-28
International immunopharmacology 2018 Aug;61:20-28
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450
Cell proliferation 2018 Aug;51(4):e12450
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Cai T, Zhang C, Zhao Z, Li S, Cai H, Chen X, Cai D, Liu W, Yan Y, Xie K, Pan H, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
(-)-Guaiol regulates autophagic cell death depending on mTOR signaling in NSCLC.
Yang X, Zhu J, Wu J, Huang N, Cui Z, Luo Y, Sun F, Pan Q, Li Y, Yang Q
Cancer biology & therapy 2018 Aug 3;19(8):706-714
Cancer biology & therapy 2018 Aug 3;19(8):706-714
HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.
Li J, Zeng C, Zheng B, Liu C, Tang M, Jiang Y, Chang Y, Song W, Wang Y, Yang C
Clinical science (London, England : 1979) 2018 Aug 16;132(15):1645-1667
Clinical science (London, England : 1979) 2018 Aug 16;132(15):1645-1667
Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease.
Huang N, Erie C, Lu ML, Wei J
Molecular and cellular neurosciences 2018 Apr;88:43-52
Molecular and cellular neurosciences 2018 Apr;88:43-52
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Shen YQ, Guerra-Librero A, Fernandez-Gil BI, Florido J, García-López S, Martinez-Ruiz L, Mendivil-Perez M, Soto-Mercado V, Acuña-Castroviejo D, Ortega-Arellano H, Carriel V, Diaz-Casado ME, Reiter RJ, Rusanova I, Nieto A, López LC, Escames G
Journal of pineal research 2018 Apr;64(3)
Journal of pineal research 2018 Apr;64(3)
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Dai C, Ciccotosto GD, Cappai R, Wang Y, Tang S, Hoyer D, Schneider EK, Velkov T, Xiao X
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Liu Y, Tang J, Liu D, Zhang L, He Y, Li J, Gao L, Tang D, Jin X, Kong D
Cell death & disease 2018 Apr 1;9(4):419
Cell death & disease 2018 Apr 1;9(4):419
Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis.
Qi M, Zhang L, Ma Y, Shuai Y, Li L, Luo K, Liu W, Jin Y
Theranostics 2017;7(18):4498-4516
Theranostics 2017;7(18):4498-4516
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.
Wu L, Zhang Q, Dai W, Li S, Feng J, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Zhou Y, Fan X, Guo C
Gastroenterology research and practice 2017;2017:9724217
Gastroenterology research and practice 2017;2017:9724217
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Dun Y, Liu S, Zhang W, Xie M, Qiu L
Oxidative medicine and cellular longevity 2017;2017:8024857
Oxidative medicine and cellular longevity 2017;2017:8024857
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
Li XC, Hu QK, Chen L, Liu SY, Su S, Tao H, Zhang LN, Sun T, He LJ
International journal of medical sciences 2017;14(13):1335-1341
International journal of medical sciences 2017;14(13):1335-1341
RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.
Muniz-Feliciano L, Doggett TA, Zhou Z, Ferguson TA
Autophagy 2017;13(12):2072-2085
Autophagy 2017;13(12):2072-2085
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Feng J, Zhang Q, Mo W, Wu L, Li S, Li J, Liu T, Xu S, Fan X, Guo C
Drug design, development and therapy 2017;11:1989-2006
Drug design, development and therapy 2017;11:1989-2006
Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway.
Zhou W, Liu L, Xue Y, Zheng J, Liu X, Ma J, Li Z, Liu Y
Frontiers in molecular neuroscience 2017;10:68
Frontiers in molecular neuroscience 2017;10:68
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Zhao Z, Zhang L, Guo XD, Cao LL, Xue TF, Zhao XJ, Yang DD, Yang J, Ji J, Huang JY, Sun XL
Frontiers in molecular neuroscience 2017;10:293
Frontiers in molecular neuroscience 2017;10:293
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction.
He Q, Li Z, Wang Y, Hou Y, Li L, Zhao J
International immunopharmacology 2017 Sep;50:208-215
International immunopharmacology 2017 Sep;50:208-215
VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy.
Su H, Yang F, Wang Q, Shen Q, Huang J, Peng C, Zhang Y, Wan W, Wong CCL, Sun Q, Wang F, Zhou T, Liu W
Molecular cell 2017 Sep 21;67(6):907-921.e7
Molecular cell 2017 Sep 21;67(6):907-921.e7
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, Hou Y, Wang T
Scientific reports 2017 Sep 18;7(1):11776
Scientific reports 2017 Sep 18;7(1):11776
HMGA2 plays an important role in Cr (VI)-induced autophagy.
Yang F, Zhao L, Mei D, Jiang L, Geng C, Li Q, Yao X, Liu Y, Kong Y, Cao J
International journal of cancer 2017 Sep 1;141(5):986-997
International journal of cancer 2017 Sep 1;141(5):986-997
The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.
Li J, Zhang Q, Li S, Dai W, Feng J, Wu L, Liu T, Chen K, Xia Y, Lu J, Zhou Y, Fan X, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:687-696
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:687-696
Mono-(2-ethylhexyl) phthalate induced ROS-dependent autophagic cell death in human vascular endothelial cells.
Liu N, Jiang L, Sun X, Yao X, Zhai X, Liu X, Wu X, Bai Y, Wang S, Yang G
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:49-56
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:49-56
An autophagic mechanism is involved in the 6-hydroxydopamine-induced neurotoxicity in vivo.
He X, Yuan W, Li Z, Feng J
Toxicology letters 2017 Oct 5;280:29-40
Toxicology letters 2017 Oct 5;280:29-40
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, Chao J, Hu G, Yao H
Autophagy 2017 Oct 3;13(10):1722-1741
Autophagy 2017 Oct 3;13(10):1722-1741
SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.
Wang M, Wu H, Li S, Xu Z, Li X, Yang Y, Li B, Li Y, Guo J, Chen H
Oncotarget 2017 Oct 27;8(52):89692-89706
Oncotarget 2017 Oct 27;8(52):89692-89706
mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis.
Wan W, You Z, Xu Y, Zhou L, Guan Z, Peng C, Wong CCL, Su H, Zhou T, Xia H, Liu W
Molecular cell 2017 Oct 19;68(2):323-335.e6
Molecular cell 2017 Oct 19;68(2):323-335.e6
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
Jin S, Tian S, Luo M, Xie W, Liu T, Duan T, Wu Y, Cui J
Molecular cell 2017 Oct 19;68(2):308-322.e4
Molecular cell 2017 Oct 19;68(2):308-322.e4
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Chen S, Wu DD, Sang XB, Wang LL, Zong ZH, Sun KX, Liu BL, Zhao Y
Cell death & disease 2017 Oct 12;8(10):e3118
Cell death & disease 2017 Oct 12;8(10):e3118
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
Xue TF, Ding X, Ji J, Yan H, Huang JY, Guo XD, Yang J, Sun XL
Journal of pharmacological sciences 2017 Nov;135(3):105-113
Journal of pharmacological sciences 2017 Nov;135(3):105-113
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Prion-like transmission of α-synuclein pathology in the context of an NFL null background.
Rutherford NJ, Brooks M, Riffe CJ, Gorion KM, Howard JK, Dhillon JS, Giasson BI
Neuroscience letters 2017 Nov 20;661:114-120
Neuroscience letters 2017 Nov 20;661:114-120
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Yang W, Li L, Huang X, Kan G, Lin L, Cheng J, Xu C, Sun W, Cong W, Zhao S, Cui S
Oncotarget 2017 Nov 17;8(58):98677-98690
Oncotarget 2017 Nov 17;8(58):98677-98690
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Ge W, Zhao K, Wang X, Li H, Yu M, He M, Xue X, Zhu Y, Zhang C, Cheng Y, Jiang S, Hu Y
Cancer cell 2017 Nov 13;32(5):561-573.e6
Cancer cell 2017 Nov 13;32(5):561-573.e6
Synergism and mechanism of Astragaloside IV combined with Ginsenoside Rg1 against autophagic injury of PC12 cells induced by oxygen glucose deprivation/reoxygenation.
Huang XP, Ding H, Yang XQ, Li JX, Tang B, Liu XD, Tang YH, Deng CQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:124-134
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:124-134
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Khan SH, Zhao D, Shah SZ, Hassan MF, Zhu T, Song Z, Zhou X, Yang L
Cellular and molecular neurobiology 2017 May;37(4):717-728
Cellular and molecular neurobiology 2017 May;37(4):717-728
Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.
Sorrentino ZA, Brooks MMT, Hudson V 3rd, Rutherford NJ, Golde TE, Giasson BI, Chakrabarty P
Molecular neurodegeneration 2017 May 29;12(1):40
Molecular neurodegeneration 2017 May 29;12(1):40
miR-29b contributes to multiple types of muscle atrophy.
Li J, Chan MC, Yu Y, Bei Y, Chen P, Zhou Q, Cheng L, Chen L, Ziegler O, Rowe GC, Das S, Xiao J
Nature communications 2017 May 25;8:15201
Nature communications 2017 May 25;8:15201
BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis.
Liu H, Cheng Y, Yang J, Wang W, Fang S, Zhang W, Han B, Zhou Z, Yao H, Chao J, Liao H
Cell death & disease 2017 Mar 9;8(3):e2657
Cell death & disease 2017 Mar 9;8(3):e2657
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
La X, Zhang L, Li Z, Yang P, Wang Y
Oncotarget 2017 Mar 28;8(13):20909-20924
Oncotarget 2017 Mar 28;8(13):20909-20924
Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells.
Zhang T, Wang T, Cai P
Molecular medicine reports 2017 Jun;15(6):3566-3574
Molecular medicine reports 2017 Jun;15(6):3566-3574
Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway.
Lin YT, Wang HC, Hsu YC, Cho CL, Yang MY, Chien CY
International journal of molecular sciences 2017 Jun 23;18(7)
International journal of molecular sciences 2017 Jun 23;18(7)
The PI3K/Akt/mTOR pathway is involved in CVB3-induced autophagy of HeLa cells.
Chang H, Li X, Cai Q, Li C, Tian L, Chen J, Xing X, Gan Y, Ouyang W, Yang Z
International journal of molecular medicine 2017 Jul;40(1):182-192
International journal of molecular medicine 2017 Jul;40(1):182-192
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.
Sun QZ, Lin GF, Li LL, Jin XT, Huang LY, Zhang G, Yang W, Chen K, Xiang R, Chen C, Wei YQ, Lu GW, Yang SY
Journal of medicinal chemistry 2017 Jul 27;60(14):6337-6352
Journal of medicinal chemistry 2017 Jul 27;60(14):6337-6352
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Wang EX, Zou BY, Shi L, Du LY, Zhu YY, Jiang YM, Ma XD, Kang XH, Wang CY, Zhen YH, Sun LD
Life sciences 2017 Jul 1;180:102-113
Life sciences 2017 Jul 1;180:102-113
Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.
Koller EJ, Brooks MM, Golde TE, Giasson BI, Chakrabarty P
Molecular neurodegeneration 2017 Jan 3;12(1):1
Molecular neurodegeneration 2017 Jan 3;12(1):1
Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils.
Ayers JI, Brooks MM, Rutherford NJ, Howard JK, Sorrentino ZA, Riffe CJ, Giasson BI
Journal of virology 2017 Jan 15;91(2)
Journal of virology 2017 Jan 15;91(2)
Propylene Glycol Alginate Sodium Sulfate Alleviates Cerulein-Induced Acute Pancreatitis by Modulating the MEK/ERK Pathway in Mice.
Zhang H, Li Y, Li L, Liu H, Hu L, Dai Y, Chen J, Xu S, Chen W, Xu X, Xu X
Marine drugs 2017 Feb 17;15(2)
Marine drugs 2017 Feb 17;15(2)
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Wang Y, Wu H, Li Z, Yang P, Li Z
Experimental cell research 2017 Feb 1;351(1):24-35
Experimental cell research 2017 Feb 1;351(1):24-35
Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.
Liu T, Zhang Z, Yu C, Zeng C, Xu X, Wu G, Huang Z, Li W
British journal of pharmacology 2017 Dec;174(23):4308-4328
British journal of pharmacology 2017 Dec;174(23):4308-4328
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course.
Tayebi N, Parisiadou L, Berhe B, Gonzalez AN, Serra-Vinardell J, Tamargo RJ, Maniwang E, Sorrentino Z, Fujiwara H, Grey RJ, Hassan S, Blech-Hermoni YN, Chen C, McGlinchey R, Makariou-Pikis C, Brooks M, Ginns EI, Ory DS, Giasson BI, Sidransky E
Molecular genetics and metabolism 2017 Dec;122(4):198-208
Molecular genetics and metabolism 2017 Dec;122(4):198-208
Comparison of the in vivo induction and transmission of α-synuclein pathology by mutant α-synuclein fibril seeds in transgenic mice.
Rutherford NJ, Dhillon JS, Riffe CJ, Howard JK, Brooks M, Giasson BI
Human molecular genetics 2017 Dec 15;26(24):4906-4915
Human molecular genetics 2017 Dec 15;26(24):4906-4915
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Scientific reports 2017 Aug 24;7(1):9289
Scientific reports 2017 Aug 24;7(1):9289
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Du C, Zhang T, Xiao X, Shi Y, Duan H, Ren Y
The Biochemical journal 2017 Aug 2;474(16):2733-2747
The Biochemical journal 2017 Aug 2;474(16):2733-2747
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1.
Yan S, Liu L, Ren F, Gao Q, Xu S, Hou B, Wang Y, Jiang X, Che Y
Cell death & disease 2017 Aug 10;8(8):e2988
Cell death & disease 2017 Aug 10;8(8):e2988
Systematic Characterization of Autophagy in Gestational Diabetes Mellitus.
Ji L, Chen Z, Xu Y, Xiong G, Liu R, Wu C, Hu H, Wang L
Endocrinology 2017 Aug 1;158(8):2522-2532
Endocrinology 2017 Aug 1;158(8):2522-2532
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.
Zhang L, Li J, Ma J, Chen X, Chen K, Jiang Z, Zong L, Yu S, Li X, Xu Q, Lei J, Duan W, Li W, Shan T, Ma Q, Shen X
Oxidative medicine and cellular longevity 2016;2016:3897250
Oxidative medicine and cellular longevity 2016;2016:3897250
Regulation of Autophagy-Related Protein and Cell Differentiation by High Mobility Group Box 1 Protein in Adipocytes.
Feng H, Yu L, Zhang G, Liu G, Yang C, Wang H, Song X
Mediators of inflammation 2016;2016:1936386
Mediators of inflammation 2016;2016:1936386
Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.
Gao J, Li M, Qin S, Zhang T, Jiang S, Hu Y, Deng Y, Zhang C, You D, Li H, Mu D, Zhang Z, Jiang C
Autophagy 2016;12(4):632-47
Autophagy 2016;12(4):632-47
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Li J, Chen K, Li S, Feng J, Liu T, Wang F, Zhang R, Xu S, Zhou Y, Zhou S, Xia Y, Lu J, Zhou Y, Guo C
Drug design, development and therapy 2016;10:619-30
Drug design, development and therapy 2016;10:619-30
Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment.
Qin L, Xu T, Xia L, Wang X, Zhang X, Zhang X, Zhu Z, Zhong S, Wang C, Shen Z
Drug design, development and therapy 2016;10:1035-45
Drug design, development and therapy 2016;10:1035-45
Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages.
Liu E, Lopez Corcino Y, Portillo JA, Miao Y, Subauste CS
Infection and immunity 2016 Sep;84(9):2616-26
Infection and immunity 2016 Sep;84(9):2616-26
Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition.
Ju JS, Jeon SI, Park JY, Lee JY, Lee SC, Cho KJ, Jeong JM
The journal of physiological sciences : JPS 2016 Sep;66(5):417-30
The journal of physiological sciences : JPS 2016 Sep;66(5):417-30
Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy.
Dai C, Tang S, Velkov T, Xiao X
Molecular neurobiology 2016 Sep;53(7):4685-700
Molecular neurobiology 2016 Sep;53(7):4685-700
Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.
Zhang Y, Shen K, Bai Y, Lv X, Huang R, Zhang W, Chao J, Nguyen LK, Hua J, Gan G, Hu G, Yao H
Autophagy 2016 Sep;12(9):1538-59
Autophagy 2016 Sep;12(9):1538-59
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Guo YJ, Dong SY, Cui XX, Feng Y, Liu T, Yin M, Kuo SH, Tan EK, Zhao WJ, Wu YC
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Sun R, Shen S, Zhang YJ, Xu CF, Cao ZT, Wen LP, Wang J
Biomaterials 2016 Oct;103:44-55
Biomaterials 2016 Oct;103:44-55
Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.
Breid S, Bernis ME, Babila JT, Garza MC, Wille H, Tamgüney G
Journal of virology 2016 Oct 15;90(20):9182-93
Journal of virology 2016 Oct 15;90(20):9182-93
Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.
Wang HS, Pei F, Chen Z, Zhang L
Journal of dental research 2016 Jun;95(6):697-703
Journal of dental research 2016 Jun;95(6):697-703
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Wang K, Zhang C, Bao J, Jia X, Liang Y, Wang X, Chen M, Su H, Li P, Wan JB, He C
Scientific reports 2016 Jun 6;6:26064
Scientific reports 2016 Jun 6;6:26064
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, Zhang J, Ji L, Ren T, An J, Liu B, Nie Y, Xing J
Autophagy 2016 Jun 2;12(6):999-1014
Autophagy 2016 Jun 2;12(6):999-1014
Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin.
Wang Y, Shi K, Zhang L, Hu G, Wan J, Tang J, Yin S, Duan J, Qin M, Wang N, Xie D, Gao X, Gao H, Zhang Z, He Q
Autophagy 2016 Jun 2;12(6):949-62
Autophagy 2016 Jun 2;12(6):949-62
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Su C, Shi Q, Song X, Fu J, Liu Z, Wang Y, Wang Y, Xia X, Song E, Song Y
Toxicology 2016 Jul 1;363-364:48-57
Toxicology 2016 Jul 1;363-364:48-57
Egr-1 promotes hypoxia-induced autophagy to enhance chemo-resistance of hepatocellular carcinoma cells.
Peng WX, Xiong EM, Ge L, Wan YY, Zhang CL, Du FY, Xu M, Bhat RA, Jin J, Gong AH
Experimental cell research 2016 Jan 1;340(1):62-70
Experimental cell research 2016 Jan 1;340(1):62-70
Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells.
Yao J, Ma C, Gao W, Liang J, Liu C, Yang H, Yan Q, Wen Q
Oncology reports 2016 Dec;36(6):3363-3370
Oncology reports 2016 Dec;36(6):3363-3370
β-asarone improves learning and memory and reduces Acetyl Cholinesterase and Beta-amyloid 42 levels in APP/PS1 transgenic mice by regulating Beclin-1-dependent autophagy.
Deng M, Huang L, Ning B, Wang N, Zhang Q, Zhu C, Fang Y
Brain research 2016 Dec 1;1652:188-194
Brain research 2016 Dec 1;1652:188-194
Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus.
Li X, Liu F, Zhang X, Shi G, Ren J, Ji J, Ding L, Fan H, Dou H, Hou Y
Cell death & disease 2016 Aug 18;7(8):e2341
Cell death & disease 2016 Aug 18;7(8):e2341
TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy.
Liu T, Tang Q, Liu K, Xie W, Liu X, Wang H, Wang RF, Cui J
Cell reports 2016 Aug 16;16(7):1988-2002
Cell reports 2016 Aug 16;16(7):1988-2002
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Liu X, Chen L, Ge J, Yan C, Huang Z, Hu J, Wen C, Li M, Huang D, Qiu Y, Hao H, Yuan R, Lei J, Yu X, Shao J
Cancer research 2016 Aug 15;76(16):4897-907
Cancer research 2016 Aug 15;76(16):4897-907
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.
Webster CP, Smith EF, Bauer CS, Moller A, Hautbergue GM, Ferraiuolo L, Myszczynska MA, Higginbottom A, Walsh MJ, Whitworth AJ, Kaspar BK, Meyer K, Shaw PJ, Grierson AJ, De Vos KJ
The EMBO journal 2016 Aug 1;35(15):1656-76
The EMBO journal 2016 Aug 1;35(15):1656-76
Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat chloride-induced hypoxia.
Sun L, Liu N, Liu SS, Xia WY, Liu MY, Li LF, Gao JX
American journal of cancer research 2015;5(9):2626-42
American journal of cancer research 2015;5(9):2626-42
Autophagy protects renal tubular cells against ischemia / reperfusion injury in a time-dependent manner.
Guan X, Qian Y, Shen Y, Zhang L, Du Y, Dai H, Qian J, Yan Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(1):285-98
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(1):285-98
Chloroquine-enhanced efficacy of cisplatin in the treatment of hypopharyngeal carcinoma in xenograft mice.
Zhao XG, Sun RJ, Yang XY, Liu DY, Lei DP, Jin T, Pan XL
PloS one 2015;10(4):e0126147
PloS one 2015;10(4):e0126147
Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.
Brun T, Li N, Jourdain AA, Gaudet P, Duhamel D, Meyer J, Bosco D, Maechler P
Human molecular genetics 2015 Sep 15;24(18):5270-84
Human molecular genetics 2015 Sep 15;24(18):5270-84
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Li J, Yang D, Wang W, Piao S, Zhou J, Saiyin W, Zheng C, Sun H, Li Y
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:97
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:97
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy.
Hunt JB Jr, Nash KR, Placides D, Moran P, Selenica ML, Abuqalbeen F, Ratnasamy K, Slouha N, Rodriguez-Ospina S, Savlia M, Ranaweera Y, Reid P, Dickey CA, Uricia R, Yang CG, Sandusky LA, Gordon MN, Morgan D, Lee DC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Nov 4;35(44):14842-60
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Nov 4;35(44):14842-60
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Li J, Wang F, Xia Y, Dai W, Chen K, Li S, Liu T, Zheng Y, Wang J, Lu W, Zhou Y, Yin Q, Lu J, Zhou Y, Guo C
Marine drugs 2015 May 27;13(6):3368-87
Marine drugs 2015 May 27;13(6):3368-87
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Yang R, Zhang M, Gustafson AR, Wang E, Cole MP, Tooley CE, Cheng A
Bioscience reports 2015 May 1;35(3)
Bioscience reports 2015 May 1;35(3)
Citreoviridin induces ROS-dependent autophagic cell death in human liver HepG2 cells.
Liu YN, Wang YX, Liu XF, Jiang LP, Yang G, Sun XC, Geng CY, Li QJ, Chen M, Yao XF
Toxicon : official journal of the International Society on Toxinology 2015 Mar;95:30-7
Toxicon : official journal of the International Society on Toxinology 2015 Mar;95:30-7
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Yue M, Hinkle KM, Davies P, Trushina E, Fiesel FC, Christenson TA, Schroeder AS, Zhang L, Bowles E, Behrouz B, Lincoln SJ, Beevers JE, Milnerwood AJ, Kurti A, McLean PJ, Fryer JD, Springer W, Dickson DW, Farrer MJ, Melrose HL
Neurobiology of disease 2015 Jun;78:172-95
Neurobiology of disease 2015 Jun;78:172-95
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice.
Ceballos-Diaz C, Rosario AM, Park HJ, Chakrabarty P, Sacino A, Cruz PE, Siemienski Z, Lara N, Moran C, Ravelo N, Golde TE, McFarland NR
Molecular neurodegeneration 2015 Jul 8;10:25
Molecular neurodegeneration 2015 Jul 8;10:25
Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice.
Rutherford NJ, Sacino AN, Brooks M, Ceballos-Diaz C, Ladd TB, Howard JK, Golde TE, Giasson BI
Molecular neurodegeneration 2015 Jul 30;10:32
Molecular neurodegeneration 2015 Jul 30;10:32
A novel antitumour strategy using bidirectional autophagic vesicles accumulation via initiative induction and the terminal restraint of autophagic flux.
Wang Y, Tai X, Zhang L, Liu Y, Gao H, Chen J, Shi K, Zhang Q, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2015 Feb 10;199:17-28
Journal of controlled release : official journal of the Controlled Release Society 2015 Feb 10;199:17-28
Induction of autophagy improves embryo viability in cloned mouse embryos.
Shen X, Zhang N, Wang Z, Bai G, Zheng Z, Gu Y, Wu Y, Liu H, Zhou D, Lei L
Scientific reports 2015 Dec 8;5:17829
Scientific reports 2015 Dec 8;5:17829
Identification and quantitative analysis of cellular proteins affected by treatment with withaferin a using a SILAC-based proteomics approach.
Narayan M, Seeley KW, Jinwal UK
Journal of ethnopharmacology 2015 Dec 4;175:86-92
Journal of ethnopharmacology 2015 Dec 4;175:86-92
Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease.
Erie C, Sacino M, Houle L, Lu ML, Wei J
The European journal of neuroscience 2015 Aug;42(3):1941-51
The European journal of neuroscience 2015 Aug;42(3):1941-51
SQSTM1 splice site mutation in distal myopathy with rimmed vacuoles.
Bucelli RC, Arhzaouy K, Pestronk A, Pittman SK, Rojas L, Sue CM, Evilä A, Hackman P, Udd B, Harms MB, Weihl CC
Neurology 2015 Aug 25;85(8):665-74
Neurology 2015 Aug 25;85(8):665-74
Knockdown of autophagy-related gene LC3 enhances the sensitivity of HepG2 cells to epirubicin.
Peng W, DU T, Zhang Z, DU F, Jin J, Gong A
Experimental and therapeutic medicine 2015 Apr;9(4):1271-1276
Experimental and therapeutic medicine 2015 Apr;9(4):1271-1276
Targeted sequencing and identification of genetic variants in sporadic inclusion body myositis.
Weihl CC, Baloh RH, Lee Y, Chou TF, Pittman SK, Lopate G, Allred P, Jockel-Balsarotti J, Pestronk A, Harms MB
Neuromuscular disorders : NMD 2015 Apr;25(4):289-96
Neuromuscular disorders : NMD 2015 Apr;25(4):289-96
Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma.
Bao LJ, Jaramillo MC, Zhang ZB, Zheng YX, Yao M, Zhang DD, Yi XF
International journal of clinical and experimental pathology 2014;7(4):1502-13
International journal of clinical and experimental pathology 2014;7(4):1502-13
Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker.
Sacino AN, Brooks M, McKinney AB, Thomas MA, Shaw G, Golde TE, Giasson BI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Sep 10;34(37):12368-78
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Sep 10;34(37):12368-78
A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease.
Gonzalez MA, Feely SM, Speziani F, Strickland AV, Danzi M, Bacon C, Lee Y, Chou TF, Blanton SH, Weihl CC, Zuchner S, Shy ME
Brain : a journal of neurology 2014 Nov;137(Pt 11):2897-902
Brain : a journal of neurology 2014 Nov;137(Pt 11):2897-902
Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells.
Yao XF, Cao J, Xu LM, Sun XC, Kang J, Yang G, Jiang LP, Geng CY, Gao CZ, Zhong LF, Ma YF
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2014 May;67:96-104
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2014 May;67:96-104
Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.
Sacino AN, Brooks M, Thomas MA, McKinney AB, McGarvey NH, Rutherford NJ, Ceballos-Diaz C, Robertson J, Golde TE, Giasson BI
Acta neuropathologica 2014 May;127(5):645-65
Acta neuropathologica 2014 May;127(5):645-65
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Sacino AN, Brooks M, Thomas MA, McKinney AB, Lee S, Regenhardt RW, McGarvey NH, Ayers JI, Notterpek L, Borchelt DR, Golde TE, Giasson BI
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10732-7
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10732-7
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
Liang JX, Ning Z, Gao W, Ling J, Wang AM, Luo HF, Liang Y, Yan Q, Wang ZY
Oncology reports 2014 Dec;32(6):2726-34
Oncology reports 2014 Dec;32(6):2726-34
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently.
Fiesel FC, Moussaud-Lamodière EL, Ando M, Springer W
Journal of cell science 2014 Aug 15;127(Pt 16):3488-504
Journal of cell science 2014 Aug 15;127(Pt 16):3488-504
mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.
Ching JK, Elizabeth SV, Ju JS, Lusk C, Pittman SK, Weihl CC
Human molecular genetics 2013 Mar 15;22(6):1167-79
Human molecular genetics 2013 Mar 15;22(6):1167-79
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein.
Sacino AN, Brooks M, McGarvey NH, McKinney AB, Thomas MA, Levites Y, Ran Y, Golde TE, Giasson BI
Acta neuropathologica communications 2013 Jul 17;1:38
Acta neuropathologica communications 2013 Jul 17;1:38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 18420-1-AP(SQSTM1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SQSTM1 antibody 18420-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-P62;SQSTM1 (IP:18420-1-AP, 3ug; Detection:18420-1-AP 1:2000) with HEK-293 cells lysate 1300ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 18420-1-AP(SQSTM1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
