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LearnNBP1-90309
antibody from Novus Biologicals
Targeting: SERPINA1
A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [8]
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- Product number
- NBP1-90309 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-90309, RRID:AB_11026804
- Product name
- Rabbit Polyclonal Serpin A1/alpha 1-Antitrypsin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Serpin A1/alpha 1-Antitrypsin antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Prognostic Significance of Lymphocyte Infiltration and a Stromal Immunostaining of a Bladder Cancer Associated Diagnostic Panel in Urothelial Carcinoma.
Amelioration of Alpha-1 Antitrypsin Deficiency Diseases with Genome Editing in Transgenic Mice.
Snail and serpinA1 promote tumor progression and predict prognosis in colorectal cancer.
Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature.
Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer.
Investigation of CCL18 and A1AT as potential urinary biomarkers for bladder cancer detection.
Furuya H, Chan OTM, Hokutan K, Tsukikawa Y, Chee K, Kozai L, Chan KS, Dai Y, Wong RS, Rosser CJ
Diagnostics (Basel, Switzerland) 2019 Dec 28;10(1)
Diagnostics (Basel, Switzerland) 2019 Dec 28;10(1)
Amelioration of Alpha-1 Antitrypsin Deficiency Diseases with Genome Editing in Transgenic Mice.
Shen S, Sanchez ME, Blomenkamp K, Corcoran EM, Marco E, Yudkoff CJ, Jiang H, Teckman JH, Bumcrot D, Albright CF
Human gene therapy 2018 Aug;29(8):861-873
Human gene therapy 2018 Aug;29(8):861-873
Snail and serpinA1 promote tumor progression and predict prognosis in colorectal cancer.
Kwon CH, Park HJ, Choi JH, Lee JR, Kim HK, Jo HJ, Kim HS, Oh N, Song GA, Park DY
Oncotarget 2015 Aug 21;6(24):20312-26
Oncotarget 2015 Aug 21;6(24):20312-26
Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature.
Zhang G, Gomes-Giacoia E, Dai Y, Lawton A, Miyake M, Furuya H, Goodison S, Rosser CJ
Diagnostic pathology 2014 Nov 12;9:200
Diagnostic pathology 2014 Nov 12;9:200
Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer.
Kwon CH, Park HJ, Lee JR, Kim HK, Jeon TY, Jo HJ, Kim DH, Kim GH, Park DY
British journal of cancer 2014 Nov 11;111(10):1993-2002
British journal of cancer 2014 Nov 11;111(10):1993-2002
Investigation of CCL18 and A1AT as potential urinary biomarkers for bladder cancer detection.
Miyake M, Ross S, Lawton A, Chang M, Dai Y, Mengual L, Alcaraz A, Giacoia EG, Goodison S, Rosser CJ
BMC urology 2013 Sep 5;13:42
BMC urology 2013 Sep 5;13:42
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Analysis in human plasma.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Analysis using Anti-SERPINA1 antibody NBP1-90309 (A) shows similar pattern to independent antibody NBP1-90308 (B).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining of human cerebral cortex shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining of human kidney shows high expression.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining in human kidney and cerebral cortex tissues using anti-SERPINA1 antibody. Corresponding SERPINA1 RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining of human testis using Anti-SERPINA1 antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining of human lung using Anti-SERPINA1 antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining of human liver using Anti-SERPINA1 antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining of human lymph node using Anti-SERPINA1 antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody [NBP1-90309] - Staining of human liver, lung, lymph node and testis using Anti-SERPINA1 antibody NBP1-90309 (A) shows similar protein distribution across tissues to independent antibody NBP1-90308 (B).
