Antibody data
- Antibody Data
- Antigen structure
- References [61]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 14787-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14787-1-AP, RRID:AB_2070970
- Product name
- CBS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CBS antibody (Cat. #14787-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hydrogen Sulfide Attenuated Sepsis-Induced Myocardial Dysfunction Through TLR4 Pathway and Endoplasmic Reticulum Stress.
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Glucose-induced decrease of cystathionine β-synthase mediates renal injuries.
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats.
Cystathionine γ-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis.
Age-related differences in responses to hydrogen sulfide in the bladder of spontaneously hypertensive rats.
Fructose Intake Impairs the Synergistic Vasomotor Manifestation of Nitric Oxide and Hydrogen Sulfide in Rat Aorta.
Sodium Tanshinone IIA Sulfonate Attenuates Erectile Dysfunction in Rats with Hyperlipidemia.
Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation.
Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide.
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.
Inhibition of endogenous hydrogen sulfide biosynthesis enhances the anti-cancer effect of 3,3'-diindolylmethane in human gastric cancer cells.
Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice.
Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p.
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase.
Arterial Hypertension and Plasma Glucose Modulate the Vasoactive Effects of Nitroso-Sulfide Coupled Signaling in Human Intrarenal Arteries.
Hydrogen sulfide-mediated resistance against water avoidance stress-induced gastritis by maintenance of gastric microbial homeostasis.
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Trophoblast H2S Maintains Early Pregnancy via Regulating Maternal-Fetal Interface Immune Hemostasis.
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
Hydrogen sulfide-induced relaxation of the bladder is attenuated in spontaneously hypertensive rats.
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes.
Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells.
Decreased Expression of Cystathionine β-Synthase Exacerbates Intestinal Barrier Injury in Ulcerative Colitis.
Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in cardiac tissues of db/db mice.
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia.
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress.
Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain.
Possible role of hydrogen sulfide as an endogenous relaxation factor in the rat bladder and prostate.
Drug resistance induces the upregulation of H(2)S-producing enzymes in HCT116 colon cancer cells.
Reduced adipose tissue H2S in obesity.
Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation.
Exogenous Hydrogen Sulfide Ameliorates Diabetes-Associated Cognitive Decline by Regulating the Mitochondria-Mediated Apoptotic Pathway and IL-23/IL-17 Expression in db/db Mice.
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
The effect of hydrogen sulfide-releasing naproxen (ATB-346) versus naproxen on formation of stress-induced gastric lesions, the regulation of systemic inflammation, hypoxia and alterations in gastric microcirculation.
Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide.
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
H(2)S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells.
Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn.
Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction.
Endogenous CBS-H2S Pathway Contributes to the Development of CCI-Induced Neuropathic Pain.
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Beetroot juice reduces infarct size and improves cardiac function following ischemia-reperfusion injury: Possible involvement of endogenous H2S.
Inhibition of RhoA-dependent pathway and contraction by endogenous hydrogen sulfide in rabbit gastric smooth muscle cells.
Neuronal regulation of expression of hydrogen sulfide-producing enzyme cystathionine β-synthase in rat spinal cord astrocytes.
Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice.
Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate.
The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity.
The inhibitory role of hydrogen sulfide in airway hyperresponsiveness and inflammation in a mouse model of asthma.
Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur.
Chen YH, Teng X, Hu ZJ, Tian DY, Jin S, Wu YM
Frontiers in physiology 2021;12:653601
Frontiers in physiology 2021;12:653601
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Glucose-induced decrease of cystathionine β-synthase mediates renal injuries.
Yu Y, Xiao L, Ren Z, Zhu G, Wang W, Jia Y, Peng A, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21576
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.
Villa E, Sahu U, O'Hara BP, Ali ES, Helmin KA, Asara JM, Gao P, Singer BD, Ben-Sahra I
Molecular cell 2021 May 20;81(10):2076-2093.e9
Molecular cell 2021 May 20;81(10):2076-2093.e9
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Lai X, Wang M, Zhu Y, Feng X, Liang H, Wu J, Nie L, Li L, Shao L
Journal of hazardous materials 2021 May 15;410:124566
Journal of hazardous materials 2021 May 15;410:124566
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats.
Yao Y, Liu T, Yin L, Man S, Ye S, Ma L
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2138-2148
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2138-2148
Cystathionine γ-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis.
Bok R, Guerra DD, Lorca RA, Wennersten SA, Harris PS, Rauniyar AK, Stabler SP, MacLean KN, Roede JR, Brown LD, Hurt KJ
Redox biology 2021 Apr;40:101827
Redox biology 2021 Apr;40:101827
Age-related differences in responses to hydrogen sulfide in the bladder of spontaneously hypertensive rats.
Zou S, Shimizu T, Yamamoto M, Shimizu S, Higashi Y, Karashima T, Saito M
International journal of urology : official journal of the Japanese Urological Association 2021 Apr;28(4):459-465
International journal of urology : official journal of the Japanese Urological Association 2021 Apr;28(4):459-465
Fructose Intake Impairs the Synergistic Vasomotor Manifestation of Nitric Oxide and Hydrogen Sulfide in Rat Aorta.
Berenyiova A, Golas S, Drobna M, Cebova M, Cacanyiova S
International journal of molecular sciences 2021 Apr 30;22(9)
International journal of molecular sciences 2021 Apr 30;22(9)
Sodium Tanshinone IIA Sulfonate Attenuates Erectile Dysfunction in Rats with Hyperlipidemia.
Zhong L, Ding W, Zeng Q, He B, Zhang H, Wang L, Fan J, He S, Zhang Y, Wei A
Oxidative medicine and cellular longevity 2020;2020:7286958
Oxidative medicine and cellular longevity 2020;2020:7286958
Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation.
Koike Y, Li B, Ganji N, Zhu H, Miyake H, Chen Y, Lee C, Janssen Lok M, Zozaya C, Lau E, Lee D, Chusilp S, Zhang Z, Yamoto M, Wu RY, Inoue M, Uchida K, Kusunoki M, Delgado-Olguin P, Mertens L, Daneman A, Eaton S, Sherman PM, Pierro A
Nature communications 2020 Oct 2;11(1):4950
Nature communications 2020 Oct 2;11(1):4950
Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide.
Yan L, Jiaqiong L, Yue G, Xiaoyong L, Xuexian T, Ming L, Yinglan L, Xinxue L, Zena H
Renal failure 2020 Nov;42(1):270-281
Renal failure 2020 Nov;42(1):270-281
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.
González-García P, Hidalgo-Gutiérrez A, Mascaraque C, Barriocanal-Casado E, Bakkali M, Ziosi M, Abdihankyzy UB, Sánchez-Hernández S, Escames G, Prokisch H, Martín F, Quinzii CM, López LC
Human molecular genetics 2020 Nov 25;29(19):3296-3311
Human molecular genetics 2020 Nov 25;29(19):3296-3311
Inhibition of endogenous hydrogen sulfide biosynthesis enhances the anti-cancer effect of 3,3'-diindolylmethane in human gastric cancer cells.
Ye F, Li X, Sun K, Xu W, Shi H, Bian J, Lu R, Ye Y
Life sciences 2020 Nov 15;261:118348
Life sciences 2020 Nov 15;261:118348
Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice.
Chen M, Zhou C, Xu H, Zhang T, Wu B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109936
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109936
Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p.
Xue WL, Chen RQ, Zhang QQ, Li XH, Cao L, Li MY, Li Y, Lin G, Chen Y, Wang MJ, Zhu YC
American journal of physiology. Cell physiology 2020 May 1;318(5):C857-C869
American journal of physiology. Cell physiology 2020 May 1;318(5):C857-C869
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase.
Peleli M, Bibli SI, Li Z, Chatzianastasiou A, Varela A, Katsouda A, Zukunft S, Bucci M, Vellecco V, Davos CH, Nagahara N, Cirino G, Fleming I, Lefer DJ, Papapetropoulos A
Biochemical pharmacology 2020 Jun;176:113833
Biochemical pharmacology 2020 Jun;176:113833
Arterial Hypertension and Plasma Glucose Modulate the Vasoactive Effects of Nitroso-Sulfide Coupled Signaling in Human Intrarenal Arteries.
Cacanyiova S, Krskova K, Zorad S, Frimmel K, Drobna M, Valaskova Z, Misak A, Golas S, Breza J, Breza J Jr, Berenyiova A
Molecules (Basel, Switzerland) 2020 Jun 23;25(12)
Molecules (Basel, Switzerland) 2020 Jun 23;25(12)
Hydrogen sulfide-mediated resistance against water avoidance stress-induced gastritis by maintenance of gastric microbial homeostasis.
Han Y, Li Y, Hu Z, Wang X, Liu J, Ren X, Yu Y, Li Y, Li W, Sun Y
MicrobiologyOpen 2020 Jan;9(1):e00951
MicrobiologyOpen 2020 Jan;9(1):e00951
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
De Cicco P, Ercolano G, Rubino V, Terrazzano G, Ruggiero G, Cirino G, Ianaro A
British journal of pharmacology 2020 Feb;177(4):884-897
British journal of pharmacology 2020 Feb;177(4):884-897
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Abdollahi Govar A, Törő G, Szaniszlo P, Pavlidou A, Bibli SI, Thanki K, Resto VA, Chao C, Hellmich MR, Szabo C, Papapetropoulos A, Módis K
British journal of pharmacology 2020 Feb;177(4):866-883
British journal of pharmacology 2020 Feb;177(4):866-883
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Sikura KÉ, Potor L, Szerafin T, Oros M, Nagy P, Méhes G, Hendrik Z, Zarjou A, Agarwal A, Posta N, Torregrossa R, Whiteman M, Fürtös I, Balla G, Balla J
British journal of pharmacology 2020 Feb;177(4):793-809
British journal of pharmacology 2020 Feb;177(4):793-809
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E
Molecular cell 2020 Dec 3;80(5):876-891.e6
Molecular cell 2020 Dec 3;80(5):876-891.e6
Trophoblast H2S Maintains Early Pregnancy via Regulating Maternal-Fetal Interface Immune Hemostasis.
Wang B, Xu T, Li Y, Wang W, Lyu C, Luo D, Yang Q, Ning N, Chen ZJ, Yan J, Chen DB, Li J
The Journal of clinical endocrinology and metabolism 2020 Dec 1;105(12)
The Journal of clinical endocrinology and metabolism 2020 Dec 1;105(12)
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, Dai T, Wu J, Xin X, Guo W, Xie Y, Mao Y, Zhu YZ
Oxidative medicine and cellular longevity 2019;2019:6173685
Oxidative medicine and cellular longevity 2019;2019:6173685
Hydrogen sulfide-induced relaxation of the bladder is attenuated in spontaneously hypertensive rats.
Zou S, Shimizu T, Yamamoto M, Shimizu S, Higashi Y, Saito M
International urology and nephrology 2019 Sep;51(9):1507-1515
International urology and nephrology 2019 Sep;51(9):1507-1515
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Módis K, Ramanujam VS, Govar AA, Lopez E, Anderson KE, Wang R, Szabo C
Biochemical pharmacology 2019 Nov;169:113604
Biochemical pharmacology 2019 Nov;169:113604
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Zeng Q, He S, Zhong L, Wang L, Cheng F, Zhang H, Hui J, Wei A
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes.
Goren I, Köhler Y, Aglan A, Pfeilschifter J, Beck KF, Frank S
Nitric oxide : biology and chemistry 2019 Jun 1;87:31-42
Nitric oxide : biology and chemistry 2019 Jun 1;87:31-42
Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells.
Chen S, Yue T, Huang Z, Zhu J, Bu D, Wang X, Pan Y, Liu Y, Wang P
Cancer letters 2019 Dec 1;466:49-60
Cancer letters 2019 Dec 1;466:49-60
Decreased Expression of Cystathionine β-Synthase Exacerbates Intestinal Barrier Injury in Ulcerative Colitis.
Chen S, Zuo S, Zhu J, Yue T, Bu D, Wang X, Wang P, Pan Y, Liu Y
Journal of Crohn's & colitis 2019 Aug 14;13(8):1067-1080
Journal of Crohn's & colitis 2019 Aug 14;13(8):1067-1080
Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in cardiac tissues of db/db mice.
Sun Y, Teng Z, Sun X, Zhang L, Chen J, Wang B, Lu F, Liu N, Yu M, Peng S, Wang Y, Zhao D, Zhao Y, Ren H, Cheng Z, Dong S, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2019 Aug 1;317(2):E284-E297
American journal of physiology. Endocrinology and metabolism 2019 Aug 1;317(2):E284-E297
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Badiei A, Sudharsan R, Santana E, Dunaief JL, Aguirre GD
Experimental eye research 2019 Apr;181:72-84
Experimental eye research 2019 Apr;181:72-84
Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia.
Pang HQ, Yue SJ, Tang YP, Chen YY, Tan YJ, Cao YJ, Shi XQ, Zhou GS, Kang A, Huang SL, Shi YJ, Sun J, Tang ZS, Duan JA
Frontiers in pharmacology 2018;9:165
Frontiers in pharmacology 2018;9:165
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Zhang GY, Lu D, Duan SF, Gao YR, Liu SY, Hong Y, Dong PZ, Chen YG, Li T, Wang DY, Cheng XS, He F, Wei JS, Li GY, Zhang QY, Wu DD, Ji XY
Oxidative medicine and cellular longevity 2018;2018:9647809
Oxidative medicine and cellular longevity 2018;2018:9647809
Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress.
Chen Y, Jin S, Teng X, Hu Z, Zhang Z, Qiu X, Tian D, Wu Y
Oxidative medicine and cellular longevity 2018;2018:6717212
Oxidative medicine and cellular longevity 2018;2018:6717212
Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain.
Bellessort B, Bachelot A, Grouthier V, De Lombares C, Narboux-Neme N, Garagnani P, Pirazzini C, Astigiano S, Mastracci L, Fontaine A, Alfama G, Duvernois-Berthet E, Levi G
Journal of pain research 2018;11:715-725
Journal of pain research 2018;11:715-725
Possible role of hydrogen sulfide as an endogenous relaxation factor in the rat bladder and prostate.
Zou S, Shimizu T, Shimizu S, Higashi Y, Nakamura K, Ono H, Aratake T, Saito M
Neurourology and urodynamics 2018 Nov;37(8):2519-2526
Neurourology and urodynamics 2018 Nov;37(8):2519-2526
Drug resistance induces the upregulation of H(2)S-producing enzymes in HCT116 colon cancer cells.
Untereiner AA, Pavlidou A, Druzhyna N, Papapetropoulos A, Hellmich MR, Szabo C
Biochemical pharmacology 2018 Mar;149:174-185
Biochemical pharmacology 2018 Mar;149:174-185
Reduced adipose tissue H2S in obesity.
Katsouda A, Szabo C, Papapetropoulos A
Pharmacological research 2018 Feb;128:190-199
Pharmacological research 2018 Feb;128:190-199
Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation.
Brown-Borg HM, Rakoczy S, Wonderlich JA, Borg KE, Rojanathammanee L
Annals of the New York Academy of Sciences 2018 Apr;1418(1):118-136
Annals of the New York Academy of Sciences 2018 Apr;1418(1):118-136
Exogenous Hydrogen Sulfide Ameliorates Diabetes-Associated Cognitive Decline by Regulating the Mitochondria-Mediated Apoptotic Pathway and IL-23/IL-17 Expression in db/db Mice.
Ma S, Zhong D, Ma P, Li G, Hua W, Sun Y, Liu N, Zhang L, Zhang W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(5):1838-1850
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(5):1838-1850
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Kuang W, Zhang X, Zhu W, Lan Z
Environmental toxicology and pharmacology 2017 Sep;54:125-132
Environmental toxicology and pharmacology 2017 Sep;54:125-132
The effect of hydrogen sulfide-releasing naproxen (ATB-346) versus naproxen on formation of stress-induced gastric lesions, the regulation of systemic inflammation, hypoxia and alterations in gastric microcirculation.
Magierowski M, Magierowska K, Surmiak M, Hubalewska-Mazgaj M, Kwiecien S, Wallace JL, Brzozowski T
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Oct;68(5):749-756
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2017 Oct;68(5):749-756
Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide.
Nalli AD, Wang H, Bhattacharya S, Blakeney BA, Murthy KS
Pharmacology research & perspectives 2017 Oct;5(5)
Pharmacology research & perspectives 2017 Oct;5(5)
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Liu S, Xin D, Wang L, Zhang T, Bai X, Li T, Xie Y, Xue H, Bo S, Liu D, Wang Z
Redox biology 2017 Oct;13:528-540
Redox biology 2017 Oct;13:528-540
Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K, Szabo C, Chao C, Hellmich MR
Cancer research 2017 Nov 1;77(21):5741-5754
Cancer research 2017 Nov 1;77(21):5741-5754
H(2)S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells.
Untereiner AA, Oláh G, Módis K, Hellmich MR, Szabo C
Biochemical pharmacology 2017 Jul 15;136:86-98
Biochemical pharmacology 2017 Jul 15;136:86-98
Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn.
Ahmad A, Druzhyna N, Szabo C
Burns : journal of the International Society for Burn Injuries 2017 Aug;43(5):1021-1033
Burns : journal of the International Society for Burn Injuries 2017 Aug;43(5):1021-1033
Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction.
Zhang Y, Yang J, Wang T, Wang SG, Liu JH, Yin CP, Ye ZQ
The journal of sexual medicine 2016 Mar;13(3):350-60
The journal of sexual medicine 2016 Mar;13(3):350-60
Endogenous CBS-H2S Pathway Contributes to the Development of CCI-Induced Neuropathic Pain.
Gui Y, Li A, Qiu B, Chen F, Chen L, Liu D, Chen S, Zhou W, Zhou H
Neurochemical research 2016 Jun;41(6):1381-9
Neurochemical research 2016 Jun;41(6):1381-9
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, Pajdo R, Kwiecien S, Brzozowski T
Pharmacological research 2016 Dec;114:235-250
Pharmacological research 2016 Dec;114:235-250
Beetroot juice reduces infarct size and improves cardiac function following ischemia-reperfusion injury: Possible involvement of endogenous H2S.
Salloum FN, Sturz GR, Yin C, Rehman S, Hoke NN, Kukreja RC, Xi L
Experimental biology and medicine (Maywood, N.J.) 2015 May;240(5):669-81
Experimental biology and medicine (Maywood, N.J.) 2015 May;240(5):669-81
Inhibition of RhoA-dependent pathway and contraction by endogenous hydrogen sulfide in rabbit gastric smooth muscle cells.
Nalli AD, Rajagopal S, Mahavadi S, Grider JR, Murthy KS
American journal of physiology. Cell physiology 2015 Mar 15;308(6):C485-95
American journal of physiology. Cell physiology 2015 Mar 15;308(6):C485-95
Neuronal regulation of expression of hydrogen sulfide-producing enzyme cystathionine β-synthase in rat spinal cord astrocytes.
Miyamoto R, Otsuguro K, Yamaguchi S, Ito S
Neuroscience research 2015 Aug;97:52-9
Neuroscience research 2015 Aug;97:52-9
Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice.
Brown-Borg HM, Rakoczy S, Wonderlich JA, Armstrong V, Rojanathammanee L
Longevity & healthspan 2014;3(1):10
Longevity & healthspan 2014;3(1):10
Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate.
Jurkowska H, Roman HB, Hirschberger LL, Sasakura K, Nagano T, Hanaoka K, Krijt J, Stipanuk MH
Amino acids 2014 May;46(5):1353-65
Amino acids 2014 May;46(5):1353-65
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The inhibitory role of hydrogen sulfide in airway hyperresponsiveness and inflammation in a mouse model of asthma.
Zhang G, Wang P, Yang G, Cao Q, Wang R
The American journal of pathology 2013 Apr;182(4):1188-95
The American journal of pathology 2013 Apr;182(4):1188-95
Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur.
Stipanuk MH, Ueki I
Journal of inherited metabolic disease 2011 Feb;34(1):17-32
Journal of inherited metabolic disease 2011 Feb;34(1):17-32
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14787-1-AP(CBS antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using CBS antibody 14787-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 14787-1-AP(CBS antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 14787-1-AP(CBS antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue