Ab170512

antibody from Aladdin Scientific Corporation

Targeting: IL1B IL-1B, IL1-BETA, IL1F2

ELISA (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Functional assay (Data presented on provider website)

Antibody Data

Product number

Ab170512

Provider

Aladdin Scientific Corporation

Product name

Canakinumab (Anti-IL-1b)

Antibody type

Recombinant

Description

Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg

Reactivity

Human, Mouse

Conjugate

Unconjugated

Vial size

10mg,1mg,5mg

Concentration

Lot by Lot

Storage

Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.