Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations [0]
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- Product number
- 66366-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- MMP2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated MMP2 antibody (Cat. #66366-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, rat, mouse, pig and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2B10D1
- Vial size
- 20ul, 150ul
Submitted references Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis.
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification.
Mechanism of Ulcerative Colitis-Aggravated Liver Fibrosis: The Activation of Hepatic Stellate Cells and TLR4 Signaling Through Gut-Liver Axis.
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
TRIM16 overexpression inhibits the metastasis of colorectal cancer through mediating Snail degradation.
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade.
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non-carcinogenic L929 fibroblast cells.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Reticulocalbin 1 is required for proliferation and migration of non-small cell lung cancer cells regulated by osteoblast-conditioned medium.
Scleraxis expressing scleral cells respond to inflammatory stimulation.
Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.
Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis.
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Lei Y, He X, Huang H, He Y, Lan J, Yang J, Liu W, Zhang T
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jan;24(1):34-47
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jan;24(1):34-47
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Wang Y, Yang Y, Zhang T, Jia S, Ma X, Zhang M, Wang L, Ma A
European journal of pharmacology 2022 Jan 15;915:174601
European journal of pharmacology 2022 Jan 15;915:174601
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification.
Zhou W, Wu C, Zhao C, Huang Z, Lu S, Fan X, Tan Y, Stalin A, You R, Liu X, Zhang J, Wu Z, Wu J
Frontiers in cell and developmental biology 2021;9:742421
Frontiers in cell and developmental biology 2021;9:742421
Mechanism of Ulcerative Colitis-Aggravated Liver Fibrosis: The Activation of Hepatic Stellate Cells and TLR4 Signaling Through Gut-Liver Axis.
Liu YF, Niu GC, Li CY, Guo JB, Song J, Li H, Zhang XL
Frontiers in physiology 2021;12:695019
Frontiers in physiology 2021;12:695019
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Bai ZM, Li XF, Yang Y, Yang YF, Lv DR, Tang LL
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
TRIM16 overexpression inhibits the metastasis of colorectal cancer through mediating Snail degradation.
Ruan L, Liu W, Yang Y, Chu Z, Yang C, Yang T, Sun J
Experimental cell research 2021 Sep 1;406(1):112735
Experimental cell research 2021 Sep 1;406(1):112735
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
Han Y, Liu D, Li L
Cancer cell international 2021 Nov 4;21(1):592
Cancer cell international 2021 Nov 4;21(1):592
Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade.
Wang X, Zou S, Ren T, Zhao LJ, Yu LF, Li XY, Yan X, Zhang LJ
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Tang X, Li Q, Li L, Jiang J
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Liu D, Han Y, Liu L, Ren X, Zhang H, Fan S, Qin T, Li L
International journal of oncology 2021 Jan;58(1):100-110
International journal of oncology 2021 Jan;58(1):100-110
Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non-carcinogenic L929 fibroblast cells.
Li X, Zhou X, Liu Y, Fan J, Huo H, Yao J, Wang L, Ma N
Oncology letters 2021 Jan;21(1):44
Oncology letters 2021 Jan;21(1):44
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Hou H, Ning F, Zhang JY, Lu Q, Zhang M, Wu P, Chen M, Lash GE
Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Reticulocalbin 1 is required for proliferation and migration of non-small cell lung cancer cells regulated by osteoblast-conditioned medium.
Fu H, Chen R, Wang Y, Xu Y, Xia C, Zhang B
Journal of cellular and molecular medicine 2021 Dec;25(24):11198-11211
Journal of cellular and molecular medicine 2021 Dec;25(24):11198-11211
Scleraxis expressing scleral cells respond to inflammatory stimulation.
Atta G, Schroedl F, Kaser-Eichberger A, Spitzer G, Traweger A, Heindl LM, Tempfer H
Histochemistry and cell biology 2021 Aug;156(2):123-132
Histochemistry and cell biology 2021 Aug;156(2):123-132
Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.
Guo W, Zhang Z, Li G, Lai X, Gu R, Xu W, Chen H, Xing Z, Chen L, Qian J, Xu S, Zeng F, Deng F
Frontiers in oncology 2020;10:544288
Frontiers in oncology 2020;10:544288
Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.
Wu L, Lin W, Liao Q, Wang H, Lin C, Tang L, Lian W, Chen Z, Li K, Xu L, Zhou R, Ding Y, Zhao L
Cell reports 2020 Oct 27;33(4):108327
Cell reports 2020 Oct 27;33(4):108327
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Li X, Ma N, Zhang Y, Wei H, Zhang H, Pang X, Li X, Wu D, Wang D, Yang Z, Zhang S
Cell death & disease 2020 May 26;11(5):399
Cell death & disease 2020 May 26;11(5):399
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
Schoenenberger AD, Tempfer H, Lehner C, Egloff J, Mauracher M, Bird A, Widmer J, Maniura-Weber K, Fucentese SF, Traweger A, Silvan U, Snedeker JG
Biomaterials 2020 Aug;249:120034
Biomaterials 2020 Aug;249:120034
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Tran BH, Yu Y, Chang L, Tan B, Jia W, Xiong Y, Dai T, Zhong R, Zhang W, Le VM, Rose P, Wang Z, Mao Y, Zhu YZ
International journal of nanomedicine 2019;14:10061-10077
International journal of nanomedicine 2019;14:10061-10077
Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis.
Zhang Y, Huang P, Liu X, Xiang Y, Zhang T, Wu Y, Xu J, Sun Z, Zhen W, Zhang L, Si Y, Liu Y
Journal of pharmacological sciences 2018 Jul;137(3):305-312
Journal of pharmacological sciences 2018 Jul;137(3):305-312
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, Zhang Z, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
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