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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [39]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [4]
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- Product number
- ABIN152329 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Matrix Metalloproteinase 2 (MMP2) (AA 400-500), (Internal Region) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Guinea Pig
- Host
- Rabbit
- Epitope
- Internal Region, AA 400-500
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Endogenous osteopontin induces myocardial CCL5 and MMP-2 activation that contributes to inflammation and cardiac remodeling in a mouse model of chronic Chagas heart disease.
Periostin promotes migration and invasion of renal cell carcinoma through the integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway.
Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork.
Effect of Bilberry Extract on Development of Form-Deprivation Myopia in the Guinea Pig.
Immediate Postnatal Overfeeding in Rats Programs Aortic Wall Structure Alterations and Metalloproteinases Dysregulation in Adulthood.
Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts.
Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model.
Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier.
The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus.
Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells.
Intracellular MMP-2 activity in skeletal muscle is associated with type II fibers.
Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.
Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A.
Delivery of lipid micelles into infarcted myocardium using a lipid-linked matrix metalloproteinase targeting peptide.
Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation.
Deep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: an in vitro and in vivo study.
Development of an aptamer-conjugated fluorescent nanoprobe for MMP2.
Time-resolved analysis of the matrix metalloproteinase 10 substrate degradome.
Plasminogen activation by staphylokinase enhances local spreading of S. aureus in skin infections.
Differential toxic responses between pristine and functionalized multiwall nanotubes involve induction of autophagy accumulation in murine lung.
Dietary α-lipoic acid prevents UVB-induced corneal and conjunctival degeneration through multiple effects.
CD43-mediated IFN-γ production by CD8+ T cells promotes abdominal aortic aneurysm in mice.
Fluorometric immunocapture assay for the specific measurement of matrix metalloproteinase-9 activity in biological samples: application to brain and plasma from rats with ischemic stroke.
Tissue- and cell-specific co-localization of intracellular gelatinolytic activity and matrix metalloproteinase 2.
High- and moderate-intensity training normalizes ventricular function and mechanoenergetics in mice with diet-induced obesity.
Matrix metalloproteinase-2 and -9 activities in the human lens epithelial cells and serum of steroid induced posterior subcapsular cataracts.
Hypoxia regulates the expression of extracellular matrix associated proteins in equine dermal fibroblasts via HIF1.
A Chinese herbal formula "Gan-Lu-Yin" suppresses vascular smooth muscle cell migration by inhibiting matrix metalloproteinase-2/9 through the PI3K/AKT and ERK signaling pathways.
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus.
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts.
MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve.
Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroitin sulfate proteoglycan.
Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression.
Increased gelatinolytic activity in keratoconus keratocyte cultures. A correlation to an altered matrix metalloproteinase-2/tissue inhibitor of metalloproteinase ratio.
Metalloproteinase-dependent neurite outgrowth within a synthetic extracellular matrix is induced by nerve growth factor.
Extraction of type-IV collagenase/gelatinase from plasma membranes of human cancer cells.
Purification of a gelatin-degrading type IV collagenase secreted by ras oncogene-transformed fibroblasts.
Caballero EP, Santamaría MH, Corral RS
Biochimica et biophysica acta. Molecular basis of disease 2018 Jan;1864(1):11-23
Biochimica et biophysica acta. Molecular basis of disease 2018 Jan;1864(1):11-23
Periostin promotes migration and invasion of renal cell carcinoma through the integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway.
Chuanyu S, Yuqing Z, Chong X, Guowei X, Xiaojun Z
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Apr;39(4):1010428317694549
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Apr;39(4):1010428317694549
Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork.
Kasetti RB, Phan TN, Millar JC, Zode GS
Investigative ophthalmology & visual science 2016 Nov 1;57(14):6058-6069
Investigative ophthalmology & visual science 2016 Nov 1;57(14):6058-6069
Effect of Bilberry Extract on Development of Form-Deprivation Myopia in the Guinea Pig.
Deng HW, Tian Y, Zhou XJ, Zhang XM, Meng J
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2016 May;32(4):196-202
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2016 May;32(4):196-202
Immediate Postnatal Overfeeding in Rats Programs Aortic Wall Structure Alterations and Metalloproteinases Dysregulation in Adulthood.
Achard V, Sanchez C, Tassistro V, Verdier M, Alessi MC, Grino M
American journal of hypertension 2016 Jun;29(6):719-26
American journal of hypertension 2016 Jun;29(6):719-26
Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts.
Hammers DW, Sleeper MM, Forbes SC, Shima A, Walter GA, Sweeney HL
Journal of the American Heart Association 2016 Aug 9;5(8)
Journal of the American Heart Association 2016 Aug 9;5(8)
Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model.
Wang Z, Xu D, Ding HF, Kim J, Zhang J, Hai T, Yan C
Oncogene 2015 Sep 17;34(38):4975-84
Oncogene 2015 Sep 17;34(38):4975-84
Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier.
Kamekura R, Nava P, Feng M, Quiros M, Nishio H, Weber DA, Parkos CA, Nusrat A
Molecular biology of the cell 2015 Sep 15;26(18):3165-77
Molecular biology of the cell 2015 Sep 15;26(18):3165-77
The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus.
Mátyás C, Németh BT, Oláh A, Hidi L, Birtalan E, Kellermayer D, Ruppert M, Korkmaz-Icöz S, Kökény G, Horváth EM, Szabó G, Merkely B, Radovits T
Cardiovascular diabetology 2015 Oct 31;14:145
Cardiovascular diabetology 2015 Oct 31;14:145
Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells.
Li PC, Sheu MJ, Ma WF, Pan CH, Sheu JH, Wu CH
Marine drugs 2015 May 15;13(5):3046-60
Marine drugs 2015 May 15;13(5):3046-60
Intracellular MMP-2 activity in skeletal muscle is associated with type II fibers.
Hadler-Olsen E, Solli AI, Hafstad A, Winberg JO, Uhlin-Hansen L
Journal of cellular physiology 2015 Jan;230(1):160-9
Journal of cellular physiology 2015 Jan;230(1):160-9
Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.
Tateossian H, Morse S, Simon MM, Dean CH, Brown SD
Disease models & mechanisms 2015 Dec;8(12):1531-42
Disease models & mechanisms 2015 Dec;8(12):1531-42
Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A.
Kendziorski JA, Belcher SM
Reproductive toxicology (Elmsford, N.Y.) 2015 Dec;58:119-30
Reproductive toxicology (Elmsford, N.Y.) 2015 Dec;58:119-30
Delivery of lipid micelles into infarcted myocardium using a lipid-linked matrix metalloproteinase targeting peptide.
Nguyen J, Sievers R, Motion JP, Kivimäe S, Fang Q, Lee RJ
Molecular pharmaceutics 2015 Apr 6;12(4):1150-7
Molecular pharmaceutics 2015 Apr 6;12(4):1150-7
Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation.
Lamarca A, Gella A, Martiañez T, Segura M, Figueiro-Silva J, Grijota-Martinez C, Trullas R, Casals N
PloS one 2014;9(6):e98998
PloS one 2014;9(6):e98998
Deep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: an in vitro and in vivo study.
Li PC, Pan CH, Sheu MJ, Wu CC, Ma WF, Wu CH
PloS one 2014;9(5):e96927
PloS one 2014;9(5):e96927
Development of an aptamer-conjugated fluorescent nanoprobe for MMP2.
Han ME, Baek S, Kim HJ, Lee JH, Ryu SH, Oh SO
Nanoscale research letters 2014 Mar 3;9(1):104
Nanoscale research letters 2014 Mar 3;9(1):104
Time-resolved analysis of the matrix metalloproteinase 10 substrate degradome.
Schlage P, Egli FE, Nanni P, Wang LW, Kizhakkedathu JN, Apte SS, auf dem Keller U
Molecular & cellular proteomics : MCP 2014 Feb;13(2):580-93
Molecular & cellular proteomics : MCP 2014 Feb;13(2):580-93
Plasminogen activation by staphylokinase enhances local spreading of S. aureus in skin infections.
Peetermans M, Vanassche T, Liesenborghs L, Claes J, Vande Velde G, Kwiecinksi J, Jin T, De Geest B, Hoylaerts MF, Lijnen RH, Verhamme P
BMC microbiology 2014 Dec 17;14:310
BMC microbiology 2014 Dec 17;14:310
Differential toxic responses between pristine and functionalized multiwall nanotubes involve induction of autophagy accumulation in murine lung.
Yu KN, Kim JE, Seo HW, Chae C, Cho MH
Journal of toxicology and environmental health. Part A 2013;76(23):1282-92
Journal of toxicology and environmental health. Part A 2013;76(23):1282-92
Dietary α-lipoic acid prevents UVB-induced corneal and conjunctival degeneration through multiple effects.
Chen BY, Lin DP, Chang LS, Huang TP, Liu HJ, Luk CP, Lo YL, Chang HH
Investigative ophthalmology & visual science 2013 Nov 5;54(10):6757-66
Investigative ophthalmology & visual science 2013 Nov 5;54(10):6757-66
CD43-mediated IFN-γ production by CD8+ T cells promotes abdominal aortic aneurysm in mice.
Zhou HF, Yan H, Cannon JL, Springer LE, Green JM, Pham CT
Journal of immunology (Baltimore, Md. : 1950) 2013 May 15;190(10):5078-85
Journal of immunology (Baltimore, Md. : 1950) 2013 May 15;190(10):5078-85
Fluorometric immunocapture assay for the specific measurement of matrix metalloproteinase-9 activity in biological samples: application to brain and plasma from rats with ischemic stroke.
Hawkins KE, DeMars KM, Yang C, Rosenberg GA, Candelario-Jalil E
Molecular brain 2013 Mar 23;6:14
Molecular brain 2013 Mar 23;6:14
Tissue- and cell-specific co-localization of intracellular gelatinolytic activity and matrix metalloproteinase 2.
Solli AI, Fadnes B, Winberg JO, Uhlin-Hansen L, Hadler-Olsen E
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2013 Jun;61(6):444-61
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2013 Jun;61(6):444-61
High- and moderate-intensity training normalizes ventricular function and mechanoenergetics in mice with diet-induced obesity.
Hafstad AD, Lund J, Hadler-Olsen E, Höper AC, Larsen TS, Aasum E
Diabetes 2013 Jul;62(7):2287-94
Diabetes 2013 Jul;62(7):2287-94
Matrix metalloproteinase-2 and -9 activities in the human lens epithelial cells and serum of steroid induced posterior subcapsular cataracts.
Alapure BV, Praveen MR, Gajjar DU, Vasavada AR, Parmar TJ, Arora AI
Molecular vision 2012;18:64-73
Molecular vision 2012;18:64-73
Hypoxia regulates the expression of extracellular matrix associated proteins in equine dermal fibroblasts via HIF1.
Deschene K, Céleste C, Boerboom D, Theoret CL
Journal of dermatological science 2012 Jan;65(1):12-8
Journal of dermatological science 2012 Jan;65(1):12-8
A Chinese herbal formula "Gan-Lu-Yin" suppresses vascular smooth muscle cell migration by inhibiting matrix metalloproteinase-2/9 through the PI3K/AKT and ERK signaling pathways.
Chien YC, Sheu MJ, Wu CH, Lin WH, Chen YY, Cheng PL, Cheng HC
BMC complementary and alternative medicine 2012 Aug 24;12:137
BMC complementary and alternative medicine 2012 Aug 24;12:137
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus.
Russo LA, Peano BJ, Trivedi SP, Cavalcanto TD, Olenchock BA, Caruso JA, Smolock AR, Vishnevsky O, Gardner RM
Reproductive biology and endocrinology : RB&E 2009 Nov 4;7:124
Reproductive biology and endocrinology : RB&E 2009 Nov 4;7:124
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML, Meltzer PS, Steeg PS
Cancer research 2007 Aug 1;67(15):7238-46
Cancer research 2007 Aug 1;67(15):7238-46
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Pakozdi A, Amin MA, Haas CS, Martinez RJ, Haines GK 3rd, Santos LL, Morand EF, David JR, Koch AE
Arthritis research & therapy 2006;8(4):R132
Arthritis research & therapy 2006;8(4):R132
Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts.
Krekoski CA, Neubauer D, Graham JB, Muir D
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Dec 1;22(23):10408-15
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Dec 1;22(23):10408-15
MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve.
Ferguson TA, Muir D
Molecular and cellular neurosciences 2000 Aug;16(2):157-67
Molecular and cellular neurosciences 2000 Aug;16(2):157-67
Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroitin sulfate proteoglycan.
Zuo J, Ferguson TA, Hernandez YJ, Stetler-Stevenson WG, Muir D
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998 Jul 15;18(14):5203-11
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998 Jul 15;18(14):5203-11
Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression.
Muir D
Clinical & experimental metastasis 1995 Jul;13(4):303-14
Clinical & experimental metastasis 1995 Jul;13(4):303-14
Increased gelatinolytic activity in keratoconus keratocyte cultures. A correlation to an altered matrix metalloproteinase-2/tissue inhibitor of metalloproteinase ratio.
Kenney MC, Chwa M, Opbroek AJ, Brown DJ
Cornea 1994 Mar;13(2):114-24
Cornea 1994 Mar;13(2):114-24
Metalloproteinase-dependent neurite outgrowth within a synthetic extracellular matrix is induced by nerve growth factor.
Muir D
Experimental cell research 1994 Feb;210(2):243-52
Experimental cell research 1994 Feb;210(2):243-52
Extraction of type-IV collagenase/gelatinase from plasma membranes of human cancer cells.
Zucker S, Moll UM, Lysik RM, DiMassimo EI, Stetler-Stevenson WG, Liotta LA, Schwedes JW
International journal of cancer 1990 Jun 15;45(6):1137-42
International journal of cancer 1990 Jun 15;45(6):1137-42
Purification of a gelatin-degrading type IV collagenase secreted by ras oncogene-transformed fibroblasts.
Spinucci C, Zucker S, Wieman JM, Lysik RM, Imhof B, Ramamurthy N, Liotta LA, Nagase H
Journal of the National Cancer Institute 1988 Nov 2;80(17):1416-20
Journal of the National Cancer Institute 1988 Nov 2;80(17):1416-20
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