Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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- Product number
- MAB902 - Provider product page
- Provider
- R&D Systems
- Product name
- Human MMP-2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects pro/active forms of human MMP-2 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) MMP-9, rhMMP-1, or rhMMP-3 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 36006
- Vial size
- 200 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references The DSCs-expressed CD82 controls the invasiveness of trophoblast cells via integrinbeta1/MAPK/MAPK3/1 signaling pathway in human first-trimester pregnancy.
High matrix metalloproteinase production correlates with immune activation and leukocyte migration in leprosy reactional lesions.
Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells.
In vitro secretion of matrix metalloprotease 9 is a prognostic marker in childhood acute lymphoblastic leukemia.
Effect of bimatoprost, latanoprost, and unoprostone on matrix metalloproteinases and their inhibitors in human ciliary body smooth muscle cells.
pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma.
Urinary biomarkers predict brain tumor presence and response to therapy.
Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions.
Oxidized low-density lipoproteins stimulate extracellular matrix metalloproteinase Inducer (EMMPRIN) release by coronary smooth muscle cells.
Li MQ, Hou XF, Shao J, Tang CL, Li DJ
Biology of reproduction 2010 May;82(5):968-79
Biology of reproduction 2010 May;82(5):968-79
High matrix metalloproteinase production correlates with immune activation and leukocyte migration in leprosy reactional lesions.
Teles RM, Teles RB, Amadeu TP, Moura DF, Mendonça-Lima L, Ferreira H, Santos IM, Nery JA, Sarno EN, Sampaio EP
Infection and immunity 2010 Mar;78(3):1012-21
Infection and immunity 2010 Mar;78(3):1012-21
Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells.
Dagouassat M, Suffee N, Hlawaty H, Haddad O, Charni F, Laguillier C, Vassy R, Martin L, Schischmanoff PO, Gattegno L, Oudar O, Sutton A, Charnaux N
International journal of cancer 2010 Mar 1;126(5):1095-108
International journal of cancer 2010 Mar 1;126(5):1095-108
In vitro secretion of matrix metalloprotease 9 is a prognostic marker in childhood acute lymphoblastic leukemia.
Schneider P, Costa O, Legrand E, Bigot D, Lecleire S, Grassi V, Vannier JP, Vasse M
Leukemia research 2010 Jan;34(1):24-31
Leukemia research 2010 Jan;34(1):24-31
Effect of bimatoprost, latanoprost, and unoprostone on matrix metalloproteinases and their inhibitors in human ciliary body smooth muscle cells.
Ooi YH, Oh DJ, Rhee DJ
Investigative ophthalmology & visual science 2009 Nov;50(11):5259-65
Investigative ophthalmology & visual science 2009 Nov;50(11):5259-65
pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma.
Struckmann K, Mertz K, Steu S, Storz M, Staller P, Krek W, Schraml P, Moch H
The Journal of pathology 2008 Mar;214(4):464-71
The Journal of pathology 2008 Mar;214(4):464-71
Urinary biomarkers predict brain tumor presence and response to therapy.
Smith ER, Zurakowski D, Saad A, Scott RM, Moses MA
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Apr 15;14(8):2378-86
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Apr 15;14(8):2378-86
Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions.
Borrelli V, di Marzo L, Sapienza P, Colasanti M, Moroni E, Cavallaro A
Surgery 2006 Sep;140(3):454-63
Surgery 2006 Sep;140(3):454-63
Oxidized low-density lipoproteins stimulate extracellular matrix metalloproteinase Inducer (EMMPRIN) release by coronary smooth muscle cells.
Haug C, Lenz C, Díaz F, Bachem MG
Arteriosclerosis, thrombosis, and vascular biology 2004 Oct;24(10):1823-9
Arteriosclerosis, thrombosis, and vascular biology 2004 Oct;24(10):1823-9
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- MMP-2 in Human Ovarian Cancer Tissue. MMP-2 was detected in immersion fixed paraffin-embedded sections of human ovarian cancer tissue using Mouse Anti-Human MMP-2 Monoclonal Antibody (Catalog # MAB902) at 10 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- MMP-2 in Human Ovarian Cancer Tissue. MMP-2 was detected in immersion fixed paraffin-embedded sections of human ovarian cancer tissue using Mouse Anti-Human MMP-2 Monoclonal Antibody (Catalog # MAB902) at 15 µg/mL overnight at 4 °C. Tissue was stained (red) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.