- GTX100656 - GeneTex PTGS2 antibody

Submitted references Deficiency in STAT1 Signaling Predisposes Gut Inflammation and Prompts Colorectal Cancer Development.

Leon-Cabrera S, Vázquez-Sandoval A, Molina-Guzman E, Delgado-Ramirez Y, Delgado-Buenrostro NL, Callejas BE, Chirino YI, Pérez-Plasencia C, Rodríguez-Sosa M, Olguín JE, Salinas C, Satoskar AR, Terrazas LI
Cancers 2018 Sep 19;10(9)

Cyclooxygenase-2 Expression and Its Correlation with Primary Tumor Size and Lymph Node Involvement in Nasopharyngeal Carcinoma.

Chrestella J, Farhat F, Daulay ER, Asnir RA, Yudhistira A, Nasution IA
Open access Macedonian journal of medical sciences 2018 Nov 25;6(11):2001-2005

3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways.

Chao W, Deng JS, Huang SS, Li PY, Liang YC, Huang GJ
International immunopharmacology 2017 Sep;50:77-86

Fisetin Regulates Nrf2 Expression and the Inflammation-Related Signaling Pathway to Prevent UVB-Induced Skin Damage in Hairless Mice.

Wu PY, Lyu JL, Liu YJ, Chien TY, Hsu HC, Wen KC, Chiang HM
International journal of molecular sciences 2017 Oct 10;18(10)

Molecular mechanisms of the effects of the ethanolic extract of Muntingia calabura Linn. fruit on lipopolysaccharide-induced pro-inflammatory mediators in macrophages.

Lin JT, Chang YY, Chen YC, Shen BY, Yang DJ
Food & function 2017 Mar 22;8(3):1245-1253

The Implication of Substance P in the Development of Tendinopathy: A Case Control Study.

Han SH, Choi W, Song J, Kim J, Lee S, Choi Y, Byun SE, Ahn T, Ahn H, Ding C, Baik L, Ward S, Ting K, Lee S
International journal of molecular sciences 2017 Jun 9;18(6)

Indirubin Inhibits LPS-Induced Inflammation via TLR4 Abrogation Mediated by the NF-kB and MAPK Signaling Pathways.

Lai JL, Liu YH, Liu C, Qi MP, Liu RN, Zhu XF, Zhou QG, Chen YY, Guo AZ, Hu CM
Inflammation 2017 Feb;40(1):1-12

The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages.

Chen CC, Lin MW, Liang CJ, Wang SH
PloS one 2016;11(7):e0158662

Docosahexaenoic acid attenuates in endocannabinoid synthesis in RAW 264.7 macrophages activated with benzo(a)pyrene and lipopolysaccharide.

Gdula-Argasińska J, Bystrowska B
Toxicology letters 2016 Sep 6;258:93-100

Resolvin D1 down-regulates CYP1A1 and PTGS2 gene in the HUVEC cells treated with benzo(a)pyrene.

Gdula-Argasińska J, Czepiel J, Totoń-Żurańska J, Jurczyszyn A, Wołkow P, Librowski T, Perucki W
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Functional Recovery in Osteoarthritic Chondrocytes Through Hyaluronic Acid and Platelet-Rich Plasma-Inhibited Infrapatellar Fat Pad Adipocytes.

Chen WH, Lin CM, Huang CF, Hsu WC, Lee CH, Ou KL, Dubey NK, Deng WP
The American journal of sports medicine 2016 Oct;44(10):2696-2705

In vitro cultures of Bacopa monnieri and an analysis of selected groups of biologically active metabolites in their biomass.

Muszyńska B, Łojewski M, Sułkowska-Ziaja K, Szewczyk A, Gdula-Argasińska J, Hałaszuk P
Pharmaceutical biology 2016 Nov;54(11):2443-2453

Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma.

Lin CS, Lee HT, Lee MH, Pan SC, Ke CY, Chiu AW, Wei YH
International journal of molecular sciences 2016 May 25;17(6)

5-Methoxytryptophan-dependent protection of cardiomyocytes from heart ischemia reperfusion injury.

Chou HC, Chan HL
Archives of biochemistry and biophysics 2014 Feb 1;543:15-22

Cardioprotective Effects of Quercetin in Cardiomyocyte under Ischemia/Reperfusion Injury.

Chen YW, Chou HC, Lin ST, Chen YH, Chang YJ, Chen L, Chan HL
Evidence-based complementary and alternative medicine : eCAM 2013;2013:364519

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Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Sample(30 ?g whole cell lysate)A:293TB:MOLT4 (GTX27912)7.5% SDS PAGEGTX100656 diluted at 1:1000The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Untreated (¡V) and treated (+) RAW264.7 whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with COX2 antibody [C3], C-term (GTX100656) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Untreated (¡V) and treated (+) THP-1 whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with COX2 antibody [C3], C-term (GTX100656) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Untreated (¡V) and treated (+) THP-1 whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with COX2 antibody [C3], C-term (GTX100656) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Untreated (¡V) and treated (+) THP-1 whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with COX2 antibody [C3], C-term (GTX100656) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Immunohistochemical analysis of paraffin-embedded U87 xenograft, using COX2(GTX100656) antibody at 1:100 dilution.

GTX100656

Antibody data