APR00164G

antibody from Leading Biology

Targeting: BRCA2 BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11

Western blot (Recommended by provider)

Antibody Data

Product number

APR00164G

Provider

Leading Biology

Product name

BRCA2 Antibody

Antibody type

Polyclonal

Description

BRCA 1 and 2 are breast cancer susceptibility proteins that play a role in DNA damage, repair, cell cycle progression, transcription and apoptosis, etc. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. BRCA2 has been shown to be required for localization of Rad51 to sites of DSBs (double stranded breaks) in DNA. Cells lacking BRCA1 and BRCA2 cannot repair DSBs thro μgh the Rad51-dependent process.

Reactivity

Human, Mouse

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.