NBP2-34406B

antibody from Novus Biologicals
Targeting: KRT6A CK6C, CK6D, K6C, K6D, KRT6C, KRT6D
Provider product page for NBP2-34406B
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-34406B - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Cytokeratin 6 Antibody
Antibody type
Monoclonal
Description
Protein A purified. This MAb recognizes a protein of 56kDa, identified as cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Biotin
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C in the dark.
KRT6A protein structure - NBP2-34406B shown in red.