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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [3]
- Immunohistochemistry [2]
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- Product number
- GTX114199 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX114199, RRID:AB_10620787
- Product name
- Glutathione Reductase antibody [N2C2], Internal
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
Submitted references Choroid plexus glutathione peroxidases are instrumental in protecting the brain fluid environment from hydroperoxides during postnatal development.
Taurine treatment prevents derangement of the hepatic γ-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism.
Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction.
Angiotensin II type 1a receptor-deficient mice develop angiotensin II-induced oxidative stress and DNA damage without blood pressure increase.
Carnosic acid protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson’s disease: Involvement of antioxidative enzymes induction
Shikonin inhibits oxidized LDL-induced monocyte adhesion by suppressing NFκB activation via up-regulation of PI3K/Akt/Nrf2-dependent antioxidation in EA.hy926 endothelial cells.
Effect of glutathione reductase knockdown in response to UVB-induced oxidative stress in human lung adenocarcinoma.
Proteomic and redox-proteomic study on the role of glutathione reductase in human lung cancer cells.
Saudrais E, Strazielle N, Ghersi-Egea JF
American journal of physiology. Cell physiology 2018 Oct 1;315(4):C445-C456
American journal of physiology. Cell physiology 2018 Oct 1;315(4):C445-C456
Taurine treatment prevents derangement of the hepatic γ-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism.
Maclean KN, Jiang H, Aivazidis S, Kim E, Shearn CT, Harris PS, Petersen DR, Allen RH, Stabler SP, Roede JR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Mar;32(3):1265-1280
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Mar;32(3):1265-1280
Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction.
Wang YY, Chen YK, Hsu YL, Chiu WC, Tsai CH, Hu SC, Hsieh PW, Yuan SF
Head & neck 2017 Jun;39(6):1055-1064
Head & neck 2017 Jun;39(6):1055-1064
Angiotensin II type 1a receptor-deficient mice develop angiotensin II-induced oxidative stress and DNA damage without blood pressure increase.
Zimnol A, Amann K, Mandel P, Hartmann C, Schupp N
American journal of physiology. Renal physiology 2017 Dec 1;313(6):F1264-F1273
American journal of physiology. Renal physiology 2017 Dec 1;313(6):F1264-F1273
Carnosic acid protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson’s disease: Involvement of antioxidative enzymes induction
Wu C, Tsai C, Chang S, Lin C, Huang L, Tsai C
Chemico-Biological Interactions 2015 January;225
Chemico-Biological Interactions 2015 January;225
Shikonin inhibits oxidized LDL-induced monocyte adhesion by suppressing NFκB activation via up-regulation of PI3K/Akt/Nrf2-dependent antioxidation in EA.hy926 endothelial cells.
Huang CS, Lin AH, Yang TC, Liu KL, Chen HW, Lii CK
Biochemical pharmacology 2015 Feb 1;93(3):352-61
Biochemical pharmacology 2015 Feb 1;93(3):352-61
Effect of glutathione reductase knockdown in response to UVB-induced oxidative stress in human lung adenocarcinoma.
Chou HC, Chan HL
Proteome science 2014 Jan 9;12(1):2
Proteome science 2014 Jan 9;12(1):2
Proteomic and redox-proteomic study on the role of glutathione reductase in human lung cancer cells.
Fan CY, Chou HC, Lo YW, Wen YF, Tsai YC, Huang H, Chan HL
Electrophoresis 2013 Dec;34(24):3305-14
Electrophoresis 2013 Dec;34(24):3305-14
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: HCT116 7.5% SDS PAGE GTX114199 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (50 ?g of whole cell lysate) A: Mouse brain 10% SDS PAGE GTX114199 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Various whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with Glutathione Reductase antibody (GTX114199) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Glutathione reductase antibody [N2C2], Internal detects Glutathione reductase protein at cytoplasm and nucleus in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. Glutathione reductase antibody [N2C2], Internal (GTX114199) diluted at 1:500.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Glutathione reductase antibody [N2C2], Internal detects Glutathione reductase protein at cytoplasm and nucleus in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. Glutathione reductase antibody [N2C2], Internal (GTX114199) diluted at 1:500.
