Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 101257 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#101257, RRID:AB_2565431
- Product name
- Brilliant Violet 605™ anti-mouse/human CD11b
- Antibody type
- Monoclonal
- Antigen
- C57BL/10 splenocytes
- Description
- CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
- Reactivity
- Human, Mouse, Rabbit
- Host
- Rat
- Conjugate
- Yellow dye
- Antibody clone number
- M1/70
- Vial size
- 50 µg
- Concentration
- 0.2 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) Brilliant Violet 605™. Data shown was gated on myeloid cell population.
- Conjugate
- Yellow dye