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- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Flow cytometry [2]
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- Product number
- ABIN258322 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Integrin alpha M (ITGAM) (AA 500-600), (Internal Region) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Internal Region, AA 500-600
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain.
The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.
Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy.
MCP-1 stimulates spinal microglia via PI3K/Akt pathway in bone cancer pain.
Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Involvement of the kynurenine pathway in human glioma pathophysiology.
Selective transfection of microglia in the brain using an antibody-based non-viral vector.
Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration.
Pioglitazone attenuates lung injury by modulating adipose inflammation.
Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation.
Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury.
Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.
Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.
IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.
Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.
Riego G, Redondo A, Leánez S, Pol O
Biochemical pharmacology 2018 Feb;148:52-63
Biochemical pharmacology 2018 Feb;148:52-63
Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain.
Ding Z, Xu W, Zhang J, Zou W, Guo Q, Huang C, Liu C, Zhong T, Zhang JM, Song Z
International journal of cancer 2017 Jan 15;140(2):411-422
International journal of cancer 2017 Jan 15;140(2):411-422
The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.
Castany S, Carcolé M, Leánez S, Pol O
PloS one 2016;11(1):e0146427
PloS one 2016;11(1):e0146427
Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy.
Biktasova AK, Dudimah DF, Uzhachenko RV, Park K, Akhter A, Arasada RR, Evans JV, Novitskiy SV, Tchekneva EE, Carbone DP, Shanker A, Dikov MM
Cancer research 2015 Nov 15;75(22):4728-41
Cancer research 2015 Nov 15;75(22):4728-41
MCP-1 stimulates spinal microglia via PI3K/Akt pathway in bone cancer pain.
Jin D, Yang JP, Hu JH, Wang LN, Zuo JL
Brain research 2015 Mar 2;1599:158-67
Brain research 2015 Mar 2;1599:158-67
Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Massó-Vallés D, Jauset T, Serrano E, Sodir NM, Pedersen K, Affara NI, Whitfield JR, Beaulieu ME, Evan GI, Elias L, Arribas J, Soucek L
Cancer research 2015 Apr 15;75(8):1675-81
Cancer research 2015 Apr 15;75(8):1675-81
Involvement of the kynurenine pathway in human glioma pathophysiology.
Adams S, Teo C, McDonald KL, Zinger A, Bustamante S, Lim CK, Sundaram G, Braidy N, Brew BJ, Guillemin GJ
PloS one 2014;9(11):e112945
PloS one 2014;9(11):e112945
Selective transfection of microglia in the brain using an antibody-based non-viral vector.
Malmevik J, Rogers ML, Nilsson M, Nakanishi Y, Rush RA, Sims NR, Muyderman H
Brain research 2014 Oct 24;1586:12-22
Brain research 2014 Oct 24;1586:12-22
Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration.
Berbegall AP, Villamón E, Tadeo I, Martinsson T, Cañete A, Castel V, Navarro S, Noguera R
Neoplasia (New York, N.Y.) 2014 Jun;16(6):471-80
Neoplasia (New York, N.Y.) 2014 Jun;16(6):471-80
Pioglitazone attenuates lung injury by modulating adipose inflammation.
Kutsukake M, Matsutani T, Tamura K, Matsuda A, Kobayashi M, Tachikawa E, Uchida E
The Journal of surgical research 2014 Jun 15;189(2):295-303
The Journal of surgical research 2014 Jun 15;189(2):295-303
Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation.
Shi X, Chen X, Li X, Lan X, Zhao C, Liu S, Huang H, Liu N, Liao S, Song W, Zhou P, Wang S, Xu L, Wang X, Dou QP, Liu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 1;20(1):151-63
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 1;20(1):151-63
Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury.
Yen YT, Yang HR, Lo HC, Hsieh YC, Tsai SC, Hong CW, Hsieh CH
Surgery 2013 May;153(5):689-98
Surgery 2013 May;153(5):689-98
Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.
Hervera A, Leánez S, Motterlini R, Pol O
Anesthesiology 2013 May;118(5):1180-97
Anesthesiology 2013 May;118(5):1180-97
Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.
Hervera A, Leánez S, Negrete R, Motterlini R, Pol O
PloS one 2012;7(8):e43693
PloS one 2012;7(8):e43693
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.
Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 2011 Sep 27;108(39):16369-74
Proceedings of the National Academy of Sciences of the United States of America 2011 Sep 27;108(39):16369-74
IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.
Chakrabarty P, Ceballos-Diaz C, Beccard A, Janus C, Dickson D, Golde TE, Das P
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5333-43
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5333-43
Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.
Chakrabarty P, Jansen-West K, Beccard A, Ceballos-Diaz C, Levites Y, Verbeeck C, Zubair AC, Dickson D, Golde TE, Das P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Feb;24(2):548-59
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Feb;24(2):548-59
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