BS4107

antibody from Bioworld Technology, Inc
Targeting: NFKBIE IKBE
Provider product page for BS4107
Western blot
Immunohistochemistry

Antibody data

Product number
BS4107 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IkB š÷ (phospho S22) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human IkB-š÷ around the phosphorylation site of Serine 22.
Description
IkB-š÷ (I-kappa-B-epsilon), also known as NFKBIE (NF°ÙB inhibitor epsilon) or IKBE, is a 500 amino acid protein that belongs to the NF°ÙB inhibitor family. Localizing to the cytoplasm, IkB-š÷ is highly expressed in spleen, testis and lung, with lower levels of expression found in kidney, pancreas, heart, placenta, brain, granulocytes and macrophages. IkB-š÷ inhibits c-Rel and NF°ÙB subunits p50, p52 and p65 by forming a complex with them in the cytoplasm, preventing them from activating genes in the nucleus. IkB-š÷ undergoes serine phosphorylation, resulting in the protein being marked for destruction via the ubiquitination pathway.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NFKBIE protein structure - BS4107 shown in red.