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- References [18]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11531-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11531-1-AP, RRID:AB_2246683
- Product name
- FBF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FBF1 antibody (Cat. #11531-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ.
FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.
Fbf1 regulates mouse oocyte meiosis by influencing Plk1.
ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia.
TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating.
Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages.
Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.
The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis.
Cep128 associates with Odf2 to form the subdistal appendage of the centriole.
A distal centriolar protein network controls organelle maturation and asymmetry.
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.
Albatross/FBF1 contributes to both centriole duplication and centrosome separation.
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells.
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis.
Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes.
Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ.
Chen C, Xu Q, Zhang Y, Davies BA, Huang Y, Katzmann DJ, Harris PC, Hu J, Ling K
Science advances 2021 Jun;7(26)
Science advances 2021 Jun;7(26)
FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.
Zhang Y, Hao J, Tarrago MG, Warner GM, Giorgadze N, Wei Q, Huang Y, He K, Chen C, Peclat TR, White TA, Ling K, Tchkonia T, Kirkland JL, Chini EN, Hu J
Cell reports 2021 Aug 3;36(5):109481
Cell reports 2021 Aug 3;36(5):109481
Fbf1 regulates mouse oocyte meiosis by influencing Plk1.
Xu Y, Xu CL, Xu ZF, Wang XJ, Liang HS, Zeng ZC, Zeng LX, Wei KN, Deng SZ, Xie SJ, Jiang J, Liu YX, Cao YK, Wang HL
Theriogenology 2021 Apr 1;164:74-83
Theriogenology 2021 Apr 1;164:74-83
ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia.
Ran J, Liu M, Feng J, Li H, Ma H, Song T, Cao Y, Zhou P, Wu Y, Yang Y, Yang Y, Yu F, Guo H, Zhang L, Xie S, Li D, Gao J, Zhang X, Zhu X, Zhou J
Developmental cell 2020 May 4;53(3):287-299.e5
Developmental cell 2020 May 4;53(3):287-299.e5
TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating.
Yan H, Chen C, Chen H, Hong H, Huang Y, Ling K, Hu J, Wei Q
Nature communications 2020 May 4;11(1):2196
Nature communications 2020 May 4;11(1):2196
Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages.
Chong WM, Wang WJ, Lo CH, Chiu TY, Chang TJ, Liu YP, Tanos B, Mazo G, Tsou MB, Jane WN, Yang TT, Liao JC
eLife 2020 Apr 3;9
eLife 2020 Apr 3;9
Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.
Lo CH, Lin IH, Yang TT, Huang YC, Tanos BE, Chou PC, Chang CW, Tsay YG, Liao JC, Wang WJ
The Journal of cell biology 2019 Oct 7;218(10):3489-3505
The Journal of cell biology 2019 Oct 7;218(10):3489-3505
The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis.
Cuenca A, Insinna C, Zhao H, John P, Weiss MA, Lu Q, Walia V, Specht S, Manivannan S, Stauffer J, Peden AA, Westlake CJ
The Journal of biological chemistry 2019 Oct 18;294(42):15418-15434
The Journal of biological chemistry 2019 Oct 18;294(42):15418-15434
Cep128 associates with Odf2 to form the subdistal appendage of the centriole.
Kashihara H, Chiba S, Kanno SI, Suzuki K, Yano T, Tsukita S
Genes to cells : devoted to molecular & cellular mechanisms 2019 Mar;24(3):231-243
Genes to cells : devoted to molecular & cellular mechanisms 2019 Mar;24(3):231-243
A distal centriolar protein network controls organelle maturation and asymmetry.
Wang L, Failler M, Fu W, Dynlacht BD
Nature communications 2018 Sep 26;9(1):3938
Nature communications 2018 Sep 26;9(1):3938
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.
Weng RR, Yang TT, Huang CE, Chang CW, Wang WJ, Liao JC
Biophysical journal 2018 Jul 17;115(2):263-275
Biophysical journal 2018 Jul 17;115(2):263-275
Albatross/FBF1 contributes to both centriole duplication and centrosome separation.
Inoko A, Yano T, Miyamoto T, Matsuura S, Kiyono T, Goshima N, Inagaki M, Hayashi Y
Genes to cells : devoted to molecular & cellular mechanisms 2018 Dec;23(12):1023-1042
Genes to cells : devoted to molecular & cellular mechanisms 2018 Dec;23(12):1023-1042
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
He K, Ma X, Xu T, Li Y, Hodge A, Zhang Q, Torline J, Huang Y, Zhao J, Ling K, Hu J
Nature communications 2018 Aug 17;9(1):3310
Nature communications 2018 Aug 17;9(1):3310
Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells.
Kazatskaya A, Kuhns S, Lambacher NJ, Kennedy JE, Brear AG, McManus GJ, Sengupta P, Blacque OE
Genetics 2017 Dec;207(4):1423-1440
Genetics 2017 Dec;207(4):1423-1440
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Fu W, Wang L, Kim S, Li J, Dynlacht BD
Cell reports 2016 Nov 1;17(6):1505-1517
Cell reports 2016 Nov 1;17(6):1505-1517
Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis.
Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K
Nature communications 2016 Feb 26;7:10777
Nature communications 2016 Feb 26;7:10777
Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes.
Wei Q, Xu Q, Zhang Y, Li Y, Zhang Q, Hu Z, Harris PC, Torres VE, Ling K, Hu J
Nature communications 2013;4:2750
Nature communications 2013;4:2750
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 11531-1-AP(FBF1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FBF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FBF1. This antibody recognizes human, mouse antigen. The FBF1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
