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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- AM8109a - Provider product page
- Provider
- Abgent
- Proper citation
- Abgent Cat#AM8109a, RRID:AB_2233422
- Product name
- IKK beta Antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant Protein
- Description
- Purified Mouse Monoclonal Antibody (Mab)
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 400 µl
- Concentration
- 0.65 mg/ml
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
Role of Src signal transduction pathways in scatter factor-mediated cellular protection.
Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10.
Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.
Tarantino N, Tinevez JY, Crowell EF, Boisson B, Henriques R, Mhlanga M, Agou F, Israël A, Laplantine E
The Journal of cell biology 2014 Jan 20;204(2):231-45
The Journal of cell biology 2014 Jan 20;204(2):231-45
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
Boisson B, Laplantine E, Prando C, Giliani S, Israelsson E, Xu Z, Abhyankar A, Israël L, Trevejo-Nunez G, Bogunovic D, Cepika AM, MacDuff D, Chrabieh M, Hubeau M, Bajolle F, Debré M, Mazzolari E, Vairo D, Agou F, Virgin HW, Bossuyt X, Rambaud C, Facchetti F, Bonnet D, Quartier P, Fournet JC, Pascual V, Chaussabel D, Notarangelo LD, Puel A, Israël A, Casanova JL, Picard C
Nature immunology 2012 Dec;13(12):1178-86
Nature immunology 2012 Dec;13(12):1178-86
Role of Src signal transduction pathways in scatter factor-mediated cellular protection.
Fan S, Meng Q, Laterra JJ, Rosen EM
The Journal of biological chemistry 2009 Mar 20;284(12):7561-77
The Journal of biological chemistry 2009 Mar 20;284(12):7561-77
Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10.
Lobry C, Lopez T, Israël A, Weil R
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 16;104(3):908-13
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 16;104(3):908-13
Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.
Panopoulos A, Harraz M, Engelhardt JF, Zandi E
The Journal of biological chemistry 2005 Jan 28;280(4):2912-23
The Journal of biological chemistry 2005 Jan 28;280(4):2912-23
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Supportive validation
- Submitted by
- Abgent (provider)
- Main image
- Experimental details
- The anti-IKKbeta Mab (Cat. #AM8109a) is used in Western blot to detect IKKbeta in Jurkat cell lysate.
- Primary Ab dilution
- 1:100~500
