BS5619

antibody from Bioworld Technology, Inc
Targeting: ARHGEF10 Gef10, KIAA0294
Provider product page for BS5619
Western blot
Immunohistochemistry

Antibody data

Product number
BS5619 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ARHGEF10 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human ARHGEF10.
Description
ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems. Defects in the gene encoding ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV), an autosomal dominant disorders that is characterized by a reduction in nerve velocities resulting from lack of proper myelination.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ARHGEF10 protein structure - BS5619 shown in red.