Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB12994 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12994, RRID:AB_10561114
- Product name
- HAP1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of HAP1.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies.
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin.
Borrell-Pagès M, Zala D, Humbert S, Saudou F
Cellular and molecular life sciences : CMLS 2006 Nov;63(22):2642-60
Cellular and molecular life sciences : CMLS 2006 Nov;63(22):2642-60
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F
Cell 2004 Jul 9;118(1):127-38
Cell 2004 Jul 9;118(1):127-38
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin.
Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA
Human molecular genetics 1997 Dec;6(13):2205-12
Human molecular genetics 1997 Dec;6(13):2205-12
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of HAP1 in mouse brain tissue lysate with HAP1 polyclonal antibody (Cat # PAB12994) at (A) 0.5 and (B) 1 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of HAP1 in human brain tissue with HAP1 polyclonal antibody (Cat # PAB12994) at 2.5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)