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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Immunohistochemistry [1]
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- Product number
- NB110-1244 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-1244, RRID:AB_791122
- Product name
- Goat Polyclonal MDA5 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Simian
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages.
TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity.
SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.
A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis.
RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease.
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling.
Identification of human metapneumovirus-induced gene networks in airway epithelial cells by microarray analysis.
mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties.
Zhu J, Duan G, Wang H, Cao M, Liu Y
Experimental cell research 2016 Jul 1;345(1):70-81
Experimental cell research 2016 Jul 1;345(1):70-81
TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity.
Chen KR, Chang CH, Huang CY, Lin CY, Lin WY, Lo YC, Yang CY, Hsing EW, Chen LF, Shih SR, Shiau AL, Lei HY, Tan TH, Ling P
The Journal of biological chemistry 2012 Sep 14;287(38):32216-21
The Journal of biological chemistry 2012 Sep 14;287(38):32216-21
SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.
Heutinck KM, Kassies J, Florquin S, ten Berge IJ, Hamann J, Rowshani AT
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 Jul;27(7):2746-54
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 Jul;27(7):2746-54
A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis.
de Koning HD, Rodijk-Olthuis D, van Vlijmen-Willems IM, Joosten LA, Netea MG, Schalkwijk J, Zeeuwen PL
The Journal of investigative dermatology 2010 Nov;130(11):2611-20
The Journal of investigative dermatology 2010 Nov;130(11):2611-20
RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease.
Sato S, Hoshino K, Satoh T, Fujita T, Kawakami Y, Fujita T, Kuwana M
Arthritis and rheumatism 2009 Jul;60(7):2193-200
Arthritis and rheumatism 2009 Jul;60(7):2193-200
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling.
Liao S, Bao X, Liu T, Lai S, Li K, Garofalo RP, Casola A
The Journal of general virology 2008 Aug;89(Pt 8):1978-1986
The Journal of general virology 2008 Aug;89(Pt 8):1978-1986
Identification of human metapneumovirus-induced gene networks in airway epithelial cells by microarray analysis.
Bao X, Sinha M, Liu T, Hong C, Luxon BA, Garofalo RP, Casola A
Virology 2008 Apr 25;374(1):114-27
Virology 2008 Apr 25;374(1):114-27
mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties.
Kang DC, Gopalkrishnan RV, Wu Q, Jankowsky E, Pyle AM, Fisher PB
Proceedings of the National Academy of Sciences of the United States of America 2002 Jan 22;99(2):637-42
Proceedings of the National Academy of Sciences of the United States of America 2002 Jan 22;99(2):637-42
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MDA5 Antibody [NB110-1244] - Staining in paraffin embedded Human Pancreas. Antibody at 10 ug/mL. Microwaved antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
