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- References [5]
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- Product number
- ABIN396674 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 2-97) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 2-97
- Isotype
- IgG
- Antibody clone number
- 6B11
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling.
Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.
NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets.
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling.
Mardakheh FK, Yekezare M, Machesky LM, Heath JK
The Journal of cell biology 2009 Oct 19;187(2):265-77
The Journal of cell biology 2009 Oct 19;187(2):265-77
Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.
Waters S, Marchbank K, Solomon E, Whitehouse C, Gautel M
FEBS letters 2009 Jun 18;583(12):1846-52
FEBS letters 2009 Jun 18;583(12):1846-52
NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets.
Kirkin V, Lamark T, Johansen T, Dikic I
Autophagy 2009 Jul;5(5):732-3
Autophagy 2009 Jul;5(5):732-3
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.
Kirkin V, Lamark T, Sou YS, Bjørkøy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Øvervatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T
Molecular cell 2009 Feb 27;33(4):505-16
Molecular cell 2009 Feb 27;33(4):505-16
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Supportive validation
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- Main image
- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
