Tissue expression
Cell line expression
Protein structure

APELA

Apelin receptor early endogenous ligand
ELA, Ende, tdl 
This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016]
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AntibodyRefsTypeWBELICCIPIHCFC
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